Are there any 5-star all-inclusive resorts in Syracuse?

Our filter tool is the easiest way to find exactly what you want. Select "5-star" and "All inclusive" to show the most luxurious properties in Syracuse where your accommodations, meals, activities and entertainment are included in the price. At these retreats, your vacation is pure extravagance from the moment you check in.

What are the top 5-star spa hotels in Syracuse?

Syracuse has a range of 5-star spa accommodations that offer therapies designed to revitalize both the mind and body. Spend your next vacation at Minareto , Ortea Palace, Sicily, Autograph Collection or Grand Hotel Ortigia Siracusa and prioritize your health and well-being.

Are there any 5-star vacation rentals in Syracuse?

You won't find any 5-star vacation rentals in Syracuse on our site, but there are a few other highly rated properties worth checking out. Browse our vacation rentals in Syracuse to book the perfect place for your stay.

Are there any 5-star hotels in downtown Syracuse?

Book a room at Grand Hotel Ortigia Siracusa . This 5-star hotel is an excellent option if you want to experience Syracuse's exciting downtown scene.

The Best 5 Star Hotels in Syracuse from SAR 432

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

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Our top choices for Syracuse 5-star hotels

Grand Hotel Ortigia Siracusa

Ortigia

Yuqi

SAR 1,474 total

includes taxes & fees

26 Jun - 27 Jun

Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Max

SAR 2,143 total

includes taxes & fees

1 Jun - 2 Jun

Caportigia Boutique Hotel

Santa Lucia

Valerie

SAR 1,011 total

includes taxes & fees

12 Jun - 13 Jun

Sauna, hot tub, Turkish bath, body treatments, body scrubs, facials

Dimora Caiammari Luxury Hotel & Spa

Syracuse

Jing

SAR 1,339 total

includes taxes & fees

2 Jun - 3 Jun

Seasonal outdoor pool, pool umbrellas, sun loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

Dena

SAR 2,357 total

includes taxes & fees

9 Jun - 10 Jun

Minareto

Syracuse

Stanislau

SAR 1,464 total

includes taxes & fees

3 Jun - 4 Jun

Wellness & Spa Hotel Principe di Fitalia

Syracuse

Jeffrey

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

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9.6/10 Exceptional! (961 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

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