A coastal town with a pier, boats, and a hillside with buildings.

Find 5 Star Hotels in Pythagorio from SAR 589

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Check availability on Pythagorio 5 Star Hotels

Tonight
19 Oct - 20 Oct
Tomorrow
20 Oct - 21 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Pythagorio 5-star hotels

A modern resort with a central pool, lounge areas, and mountain views.
A spa area with two massage tables, a stone floor, and a bamboo partition.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.

1. Casa Cook Samos

Casa Cook Samos
Samos
United States
ercan
SAR 868
SAR 1,014 total
includes taxes & fees
28 Oct - 29 Oct
Casa Cook Samos
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.
A beach with rows of sunbeds and thatched umbrellas, a clear blue sea, and mountains in the background.
A serene outdoor setting with a pool, a person in a white dress, and a view of the sea.

2. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
Germany
Artsem
Proteas Blu Resort - Adults Only
A beach with rows of beige lounge chairs and umbrellas, a clear sky, and a calm sea with a distant mountain.
A poolside table with a meal, a drink, and a view of a pool and mountains.
A modern kitchen with a central island, pendant lighting, and a tiled backsplash.
A coastal hotel with a swimming pool, surrounded by greenery and overlooking the sea.

3. Doryssa Seaside Resort

Doryssa Seaside Resort
Samos
United States
Athanasios
Doryssa Seaside Resort
An infinity pool with lounge chairs and a view of a coastal town.
A bar area with stools, a counter, and bottles.
A modern interior with a dark wood reception desk, a sofa, a large abstract painting, and a potted plant.
A modern multi-story building with a landscaped courtyard, featuring a mix of flat and sloped roofs, and a variety of plants and trees.

4. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
SAR 589
SAR 708 total
includes taxes & fees
23 Oct - 24 Oct
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Pythagorio.
Hydrele Beach Hotel

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Samian Mare Hotel Suites & Spa

Samian Mare Hotel Suites & Spa

Kanari 123 Samos Samos Island
SAR 499
SAR 589 total
26 Oct - 27 Oct
includes taxes & fees
9.2/10 Wonderful! (37 reviews)
Samian Mare Hotel Suites & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Pythagorio

The ancient harbor town showcases Pythagoras' legacy at its archaeological museum and the impressive remains of Tunnel of Eupalinos. Waterfront tavernas serve fresh seafood beside bobbing fishing boats, while nearby beaches offer perfect swimming spots.

See all hotels in Pythagorio
A coastal town with a pier, boats, and a hillside with buildings.

Top Pythagorio Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Pythagorio?
You can find various pricing options for 5-star hotels in Pythagorio on Expedia. How much you'll pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your desired dates and make use of our pricing and other filters to find the ideal luxury stay.
  • Search for the lowest price per night from SAR 589
What makes a hotel 5 stars in Pythagorio?
Flawless guest service is at the heart of every 5-star hotel in Pythagorio. From the instant you arrive, staff attend to your every need, whether recommending activities and tours or providing in-room massage treatments. Also, hotels have to feature top-rate conveniences to meet the standard for a 5-star rating. These can include luxury bath products, spa facilities, pools, gastronomic kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Pythagorio?
Use our filter tool to find a high-end retreat in Pythagorio where everything you need is included in the price. From there, refine your results for resorts that have a 5-star rating and are deemed "All inclusive." The first thing on the itinerary at these stays? Pure indulgence and relaxation.