Photo by Cindy Keese

Find 4 Star Hotels in Seneca, SC from SARĀ 671

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Check availability on Seneca 4 Star Hotels

Tonight
28 Jun - 29 Jun
Tomorrow
29 Jun - 30 Jun
Next weekend
4 Jul - 6 Jul
In two weeks
11 Jul - 13 Jul

Compare Seneca 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | 1 bedroom, in-room safe, blackout drapes, soundproofing

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (609)
"I love the location - it can't be beat if you are visiting/touring the university. The staff is so friendly and helpful and the restaurant has great food! I always love our stay at the Shepherd!"
The price is SARĀ 671
SARĀ 745 total
includes taxes & fees
1 Jul - 2 Jul
The Shepherd Hotel Downtown Clemson
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (523)
"Very friendly staff, great location, great room and very clean! "
The Abernathy of Clemson
Liberty Hall Bed and Breakfast
Restaurant

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (65)
"In town for a recent college visit. Great location in a stunning historic BNB. Breakfast was wonderful and customer service was exceptional. Would absolutely recommend staying here and plan to stay again."
Liberty Hall Bed and Breakfast
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
Lake Hartwell Frank Howard Home Clemson
Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace

Lake Hartwell Frank Howard Home Clemson

4.0 star property
Lake Hartwell Frank Howard Home Clemson
Belvedere
Family House, 4 Bedrooms, Patio, Courtyard View | Terrace/patio

Belvedere

4.0 star property
8.0 out of 10, Very Good, (1)
"Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? "
Belvedere
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
Pendleton
Comfort House, 3 Bedrooms, Non Smoking, Fireplace | Living room | 65-inch Smart TV with cable channels, fireplace, Netflix

Pendleton

4.0 star property
Pendleton
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Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Seneca?
To book a 4-star hotel in Seneca that fits your budget, use Expedia's handy search filters. Check out the available options during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly stay first.

  • Search for the lowest price from SARĀ 671

What's the difference between 5-star and 4-star hotels in Seneca?
If you decide to vacation at a 4-star hotel in Seneca, you'll usually find lots of amenities to make sure you're relaxed, such as a gym, pool and restaurant. You can look forward to excellent service and deluxe accommodations. Choose a 5-star hotel and you'll get a few extra perks --- think around-the-clock concierge, on-site spas and opulent turndown services. You'll most likely get additional amenities and first-class services at a 5-star stay, but both are fabulous options for luxury guests.
Does Seneca have any 4-star all-inclusive resorts?
Enjoy a carefree vacation experience where just about everything is included in the one rate by using our "All inclusive" filter. Keeping to your budget is easy when your accommodations, meals and many activities are already taken care of. Eager for more ideas? Browse the amazing offers on Expedia's standard 4-star resorts in and around Seneca.