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Compare 179 Vacation Homes in St. Charles with updated reviews, rates, and availability.

Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
Home Front
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
10.0 out of 10, Exceptional, (7)
"Very clean and spacious. The kids loved the ping pong table and games. Supplies were exceptional. Great location near parks and downtown. We would totally recommend this stay to friends and relatives. 5stars all around"
Delightful family home near pool, playground, park, nature center 1.6 mi to Mayo
Root River Retreat
Living room / family room . Sofa, chairs , pub table and Tv
Root River Retreat
10.0 out of 10, Exceptional, (22)
"This place is great. Very quiet. Nicely furnished. Great cookies upon arrival. Nice cold water bottles in the frig and plenty of coffee. Would highly recommend"
Root River Retreat
Magical Nest Hideaway
Bathroom
Magical Nest Hideaway
10.0 out of 10, Exceptional, (97)
"I couldn’t be happier with our stay in the beautiful Magical Nest! Our hosts were exquisitely friendly, our studio was cute, cozy, spotless, and everything we could possibly want. I would DEFINITELY stay here again in the future! THANK YOU!!"
Magical Nest Hideaway
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Bluffside cottage with gorgeous river views
Front view of house
Bluffside cottage with gorgeous river views
10.0 out of 10, Exceptional, (5)
"A great little house on the Mississippi. Very clean and tastefully decorated. The view of the Mississippi and the sunsets was fantastic."
Bluffside cottage with gorgeous river views
Comfortable and Bright
Exterior
Comfortable and Bright
10.0 out of 10, Exceptional, (13)
"The house looks deceptively small, but there is lots of space! The deck and outdoor furniture were really nice and much appreciated. The whole house was clean and comfy. Host was very responsive. Also, really liked having a garage."
Comfortable and Bright
Century Cottage-PERFECT for Mayo & downtown visitors!
Cozy and spacious
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (84)
"Nice stay! Super responsive hosts!"
Century Cottage-PERFECT for Mayo & downtown visitors!
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Exterior
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Dinning room seats 6
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
9.8 out of 10, Exceptional, (34)
"We were very pleased with having this house to return to every day. We were here for Dr. Appointments for 1 month and this was perfect. It had everything we could have wanted or needed. We loved the trails right outside the door that can take you all over the city. Great location and very nice neighborhood."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
1 mi. from Mayo Clinic; Cozy, Clean
1 mi. from Mayo Clinic; Cozy, Clean
9.8 out of 10, Exceptional, (81)
"We were very happy with this quaint home. Very nice neighborhood and convenient location to groceries and restaurants. Well stocked kitchen. Was very nice to be able to do laundry."
1 mi. from Mayo Clinic; Cozy, Clean
MCR is a property that features seclusion and privacy that is hard to find.
MCR is a property that features seclusion and privacy that is hard to find.
10.0 out of 10, Exceptional, (74)
"This is our third stay at Money Creek Ranch and we will be back! Amy is THE BEST attentive host that thinks of all the details to make our stay pleasant. We all have our favorite spot here- a young one on the swing, a family member in the hammock, someone reading on the deck, and me around the fire pit star gazing between the bluffs. This is hands down the best place for gatherings, nature viewing, and relaxing. The lodge has enough room for everyone. Not to mention you are close enough to town...
MCR is a property that features seclusion and privacy that is hard to find.
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
Living area
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
9.8 out of 10, Exceptional, (6)
"Stayed here 3 nights, following MAYO visit. Comfortable living room, kitchen, bed and bath all on main floor. We enjoyed watching our dog play with the bunnies from the enclosed deck."
The price is SAR 655
SAR 1,349 total
includes taxes & fees
14 Jum. II - 15 Jum. II
Charming 2 Bed 1 Bath Home W/Fully Fenced in Back yard
7 blks Mayo Gonda 8 blks St Mary 3 Bed Main Floor 1 more downstairs 2 Bath
Kitchen
7 blks Mayo Gonda 8 blks St Mary 3 Bed Main Floor 1 more downstairs 2 Bath
9.6 out of 10, Exceptional, (5)
"Quaint little house. Bigger inside than it looks like outside. Perfect place for our short stay. Thank you."
The price is SAR 446
SAR 982 total
includes taxes & fees
24 Jum. II - 25 Jum. II
7 blks Mayo Gonda 8 blks St Mary 3 Bed Main Floor 1 more downstairs 2 Bath
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Welcome to the Village House Inn. Whole house vacation rental.
Charming Brick Farmhouse with a Touch of Elegance. -Winona
9.8 out of 10, Exceptional, (108)
"Absolutely wonderful in everything, even the weather cooperated. Samantha is an awesome contact and host. We'll be back!"
The price is SAR 1,313
SAR 2,070 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Charming Brick Farmhouse with a Touch of Elegance. -Winona
Sweet & Chic, 3 Bd, Pet Friendly, 3 Miles to Mayo
Sunny sitting area in living room
Sweet & Chic, 3 Bd, Pet Friendly, 3 Miles to Mayo
10.0 out of 10, Exceptional, (18)
"Enjoyed our stay ,Becca was always quite responsive. Pet friendly for the "girls". Reasonably priced. We recommend"
Sweet & Chic, 3 Bd, Pet Friendly, 3 Miles to Mayo
Charming 3 bedroom home near Mayo
Living area
Charming 3 bedroom home near Mayo
9.8 out of 10, Exceptional, (8)
"We had a great stay in Rochester. This cozy home was on a quiet street, but near grocery stores, restaurants and other amenities. The home was clean and surprisingly well stocked! Property owners were great at communicating with us, even during Easter! Would definitely stay here again!"
Charming 3 bedroom home near Mayo
Beautifully Designed Space. 1 Mile to Mayo Clinic.
Kitchen with granite counters and Keurig® coffee maker.
Beautifully Designed Space. 1 Mile to Mayo Clinic.
10.0 out of 10, Exceptional, (9)
"Very clean, well appointed home. Nice quiet neighborhood close to Mayo Clinic. I would recommend this to everyone."
Beautifully Designed Space. 1 Mile to Mayo Clinic.
Your Stay at 709-Mayo Discount!
Private kitchen
Your Stay at 709-Mayo Discount!
10.0 out of 10, Exceptional, (17)
"We were contacted by host several times after making reservation. He offered assistance, information, and advice for our stay. Broc was immediately accessible throughout our stay, outstanding host. Property is five short blocks from Mayo Clinic (Methodist Hospital Campus, downtown). Area is walkable, clean, and appeared to be quiet and safe. Within four blocks of subway and skyway access. House is old, located in well established, older part of town. Modern kitchen appliances (gas cooking)....
Your Stay at 709-Mayo Discount!
Half a block from the River! Access to private dock coming summer of 2024!
Room
Half a block from the River! Access to private dock coming summer of 2024!
Half a block from the River! Access to private dock coming summer of 2024!
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
You'll have endless fun in our endless pool! Overlooks the Mississippi River!
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
10.0 out of 10, Exceptional, (50)
"My family and I are so happy we found this house for my Mom’s birthday weekend! The location is great. It’s very convenient if you like to golf, it’s in a quiet neighborhood and has a beautiful view. We loved the sunroom as a gathering space and had fun using the arcade games, pool, and deck. The space itself was clean and checking in was easy! Thank you for a great stay, we would happily choose to stay here again if we find ourselves back in Wabasha!"
Sunrise on Skyline - Indoor Pool - Arcades - Amazing Views!
Cozy, modern 2 bedroom with laundry,+ walk to mayo
Kitchen
Cozy, modern 2 bedroom with laundry,+ walk to mayo
9.4 out of 10, Exceptional, (6)
"Awesome host’s with great communication. The home is very comfortable, must be okay with stairs. Clean, great beds, open feel with good lighting and windows throughout. Love the front porch. All appliances in working order, stocked kitchen, solid internet. Just shy of a mile walk downtown or too Main Clinic buildings. Close to river walk, felt safe. Good neighborhood. Would definitely recommend"
Cozy, modern 2 bedroom with laundry,+ walk to mayo
Don't see what you're looking for?
See all available properties in St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in St. Charles

The Berkman
Lobby
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (212)
"Great place but HIGHLY over priced."
The price is SAR 638
SAR 742 total
includes taxes & fees
17 Jum. II - 18 Jum. II
The Berkman
Broadway Plaza, Trademark Collection by Wyndham
Room
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2 out of 10, Wonderful, (136)
"We loved the space!"
The price is SAR 571
SAR 878 total
includes taxes & fees
21 Jum. II - 22 Jum. II
Broadway Plaza, Trademark Collection by Wyndham
Heritage hideaway-Secluded Log Cabin
Front patio area with charcoal grill
Heritage hideaway-Secluded Log Cabin
10.0 out of 10, Exceptional, (329)
"We had the BEST most PEACEFUL time staying here and driving around the beautiful country sides, visits the adorable towns, buying Amish wares and listening to the tree frogs at night. The cabin is serene, with charm, rustic details and all the amenities you could need from cookware to lots of cozy linens. The beds and pillows were great and the view is, just the absolute best. WE. WILL. BE. BACK! *not to threaten the hosts with the bold text, but we just cannot wait!"
Heritage hideaway-Secluded Log Cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent reviews of St. Charles hotels
Expedia verified reviews

Quality Inn near Medical Center

Quality Inn near Medical Center

5/5 Excellent
"We had four rooms on our reservation they were all clean great friendly staff breakfast was good pool was great kids enjoyed it The hotel was a good experience with everything we'll stay there again"
A verified traveler stayed at Quality Inn near Medical Center
Posted 14 hours ago
Quality Inn near Medical Center