Southern Illinois Vacations
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Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
If you're spending some time in Eastport, Splash City Family Waterpark and Gateway Conference Center are top sights worth seeing.
Find the Best Southern Illinois Vacation Packages
Southern Illinois Hotel Deals
Drury Plaza Hotel Mt. Vernon
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is SAR 473 per night from May 19 to May 20
SAR 473
SAR 532 total
includes taxes & fees
19 May - 20 May
9.6/10 Exceptional! (1,310 reviews)
"Will definitely stay here in the future."
Reviewed on 6 May 2025
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is SAR 191 per night from May 25 to May 26
SAR 191
SAR 220 total
includes taxes & fees
25 May - 26 May
7.6/10 Good! (1,006 reviews)
"It was very close to where I was visiting family."
Reviewed on 6 May 2025
Quality Inn & Suites near St. Louis and I-255
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is SAR 252 per night from May 14 to May 15
SAR 252
SAR 285 total
includes taxes & fees
14 May - 15 May
7.4/10 Good! (1,003 reviews)
"Nice and clean"
Reviewed on 5 May 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Southern Illinois
Southern Illinois University
4.5/5(173 reviews)
Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
Garden of the Gods Recreation Area
5/5(6 reviews)
Explore the great outdoors at Garden of the Gods Recreation Area, a lovely green space in Equality. While you're in the area, stroll along the riverfront.
Cahokia Mounds State Historic Site
4.5/5(4 reviews)
You can learn about the history of Collinsville when you stop by Cahokia Mounds State Historic Site. Discover the great live music in this walkable area, or seek out the local tours.