Southeastern Indiana Vacations

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Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

Find hotels in West Main Historic District

Find the Best Southeastern Indiana Vacation Packages

Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North
Radisson Hotel Louisville North
3 out of 5
505 Marriott Drive, Clarksville, IN
Fully refundableReserve now, pay when you stay
The price is SAR 227 per night from May 13 to May 14
SAR 227
SAR 256 total
includes taxes & fees
13 May - 14 May
6.8/10 (2,036 reviews)
"we were very suitable for me and My sisters the only thing negative is that we could get more towels in our room"

Reviewed on 4 May 2025

Radisson Hotel Louisville North
Sheraton Louisville Riverside by Marriott
Sheraton Louisville Riverside by Marriott
3.5 out of 5
700 West Riverside Drive, Jeffersonville, IN
Fully refundableReserve now, pay when you stay
The price is SAR 379 per night from May 18 to May 19
SAR 379
SAR 428 total
includes taxes & fees
18 May - 19 May
8/10 Very Good! (1,000 reviews)
"Clean and quiet!"

Reviewed on 23 April 2025

Sheraton Louisville Riverside by Marriott
Comfort Inn & Suites Clarksville - Louisville North
Comfort Inn & Suites Clarksville - Louisville North
2.5 out of 5
1485 Broadway St, Clarksville, IN
Fully refundableReserve now, pay when you stay
The price is SAR 347 per night from May 18 to May 19
SAR 347
SAR 393 total
includes taxes & fees
18 May - 19 May
8.8/10 Excellent! (863 reviews)
"Enjoyed the comfort and ease of the hotel. Later check out allowed kids to enjoy pool longer before heading hone"

Reviewed on 3 May 2025

Comfort Inn & Suites Clarksville - Louisville North
See all 1,039 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southeastern Indiana

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

4.5/5(606 reviews)

You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.

Louisville Slugger Museum
Helped celebrate the Belle of Louisville's 100th birthday with a cruise up the Ohio River.

Louisville Waterfront Park

4.5/5(301 reviews)

After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.

Louisville Waterfront Park
Doc Crow's is perfect downtown spot for brisket and barbeque and has the tastiest drinks, especially the Man on Fire

Whiskey Row

Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.

Whiskey Row