A dam, river, forest, and agricultural fields.

Santee Vacation Rentals

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Check prices for these dates

In two weeks
17 Jul - 19 Jul
In two months
28 Aug - 30 Aug
In three months
25 Sep - 27 Sep
In four months
23 Oct - 25 Oct

Our top choices for Santee vacation rentals

Terrace/patio

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Santee
8.4 out of 10, Very Good, (5 reviews)
The price is SAR 716
SAR 1,854 total
includes taxes & fees
6 Jul - 7 Jul
LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks
Property grounds

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (15 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
The price is SAR 864
SAR 1,930 total
includes taxes & fees
19 Jul - 20 Jul
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Smart TV, offices

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (44 reviews)
"This was our first long trip with our dog and she loved the place! Fenced in yard and home was cozy and dog friendly. Loved the farmhouse style and large bedrooms and baths. "
United States
Lori B.
The price is SAR 642
SAR 1,571 total
includes taxes & fees
9 Jul - 10 Jul
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Exterior

2 Full Beds Non-Smoking

2 Full Beds Non-Smoking
St George, SC
The price is SAR 315
SAR 350 total
includes taxes & fees
2 Aug - 3 Aug
2 Full Beds Non-Smoking
Fridge, microwave, oven, stovetop

Hobbs Haven at Lake Marion

Hobbs Haven at Lake Marion
Summerton
9.4 out of 10, Exceptional, (13 reviews)
"Great location and host."
United States
Jay M.
The price is SAR 548
SAR 1,413 total
includes taxes & fees
6 Jul - 7 Jul
Hobbs Haven at Lake Marion
Beach

Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (23 reviews)
"Enjoyed the stay. Out in the country, Great!"
United States
Marty D.
The price is SAR 469
SAR 696 total
includes taxes & fees
3 Aug - 4 Aug
Country Resting Spot just off I95. 12 miles west on hwy 6.
Panoramic Tent | Lake view

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (94 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
The price is SAR 285
SAR 327 total
includes taxes & fees
9 Jul - 10 Jul
Bells Marina & Resort
Interior

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301

Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Bowman
9.8 out of 10, Exceptional, (33 reviews)
"Will stay again."
United States
Robert B.
The price is SAR 287
SAR 611 total
includes taxes & fees
12 Jul - 13 Jul
Beautiful country cottage with ease of access! Minutes to I-26, I-95 and Hwy 301
Property grounds

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (148 reviews)
"Nice place, friendly hosts!"
United States
Dan R.
The price is SAR 422
SAR 777 total
includes taxes & fees
6 Jul - 7 Jul
Pet friendly country cottage with large fenced-in yard & horses on property
Smart TV, books

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
The price is SAR 432
SAR 688 total
includes taxes & fees
5 Jul - 6 Jul
Modern apartment overlooking historic downtown Elloree, SC.
Property grounds

Orangeburg SC|Full Bed

Orangeburg SC|Full Bed
Orangeburg SC
10.0 out of 10, Exceptional, (40 reviews)
"Everything appeared clear cut here, no unexpected costs! It also felt reassuring knowing we could park free right on site too."
United States
Anonymous traveler
The price is SAR 262
SAR 317 total
includes taxes & fees
5 Jul - 6 Jul
Orangeburg SC|Full Bed
Miscellaneous

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina

Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
Eutaw Springs
The price is SAR 532
SAR 755 total
includes taxes & fees
12 Jul - 13 Jul
Lakeside Glamping Tent with Kayaks & Spacious Deck in Eutaw Springs, South Carolina
TV, fireplace

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8

Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Summerton
The price is SAR 826
SAR 2,001 total
includes taxes & fees
5 Jul - 6 Jul
Private Farm Stay on 30-Acres with Fish Pond + Sleeps 8
Outdoor dining

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.4 out of 10, Very Good, (16 reviews)
"Great place to stay. "
United States
Scott J.
The price is SAR 287
SAR 498 total
includes taxes & fees
6 Jul - 7 Jul
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Private kitchen

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (13 reviews)
"Great stay!"
United States
Hayden S.
The price is SAR 469
SAR 604 total
includes taxes & fees
10 Jul - 11 Jul
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Terrace/patio

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.4 out of 10, Good, (8 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
The price is SAR 319
SAR 533 total
includes taxes & fees
9 Jul - 10 Jul
Cabin at the lake in Rimini, SC
Room

Orangeburg SC|Queen Bed

Orangeburg SC|Queen Bed
Orangeburg SC
10.0 out of 10, Exceptional, (51 reviews)
"Decent value considering price point, met needs adequately without fussing over luxury levels or extra frills throughout duration of stay."
United States
Anonymous traveler
The price is SAR 304
SAR 367 total
includes taxes & fees
5 Jul - 6 Jul
Orangeburg SC|Queen Bed
TV, table tennis

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
The price is SAR 468
SAR 1,627 total
includes taxes & fees
5 Jul - 6 Jul
Turtle Cove - Lake Living on Lake Marion
Property grounds

Orangeburg SC |King Bed

Orangeburg SC |King Bed
Orangeburg SC
10.0 out of 10, Exceptional, (48 reviews)
"Zero complaints about our two night stay here, comfortable enough sleeping arrangements allowed everyone to recharge before our next adventure."
United States
Anonymous traveler
The price is SAR 325
SAR 393 total
includes taxes & fees
5 Jul - 6 Jul
Orangeburg SC |King Bed
Exterior

Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina

Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina
Eutaw Springs
The price is SAR 630
SAR 800 total
includes taxes & fees
5 Jul - 6 Jul
Tiny Home Retreat with Lake Views & Private Patio in Eutaw Springs, South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Best Western Plus Santee Inn

Best Western Plus Santee Inn

10/10 Excellent
"What a super clean cute place to stay. If you like the idea of parking outside your door which I do. It’s so nice. It’s very clean and safe and well taken care of. Cute little area it’s in. A golf course next door. I would stay here again for sure. Priced really well and plenty of restaurants near by."
Michael 1-night trip
Posted 12 hours ago
Best Western Plus Santee Inn

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: Visitors like this Santee vacation home rental. It is located on a lake and has a patio, a selection of games, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Another good choice for your trip to Santee is Patio + Pool Table: Lake Marion Getaway.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee State Park are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.