A tropical island with a beach, clear turquoise waters, and lush greenery.

Find hotels in Santa Isabel from SAR 777

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sep - 6 Sep
In two weeks
11 Sep - 13 Sep

Filter by

Star rating

Guest rating

Our top choices for Santa Isabel hotels

1. Cabins on paradise San Blas island

Cabins on paradise San Blas island
Narganá
SAR 1,010
SAR 1,111 total
includes taxes & fees
31 Aug - 1 Sep
Cabins on paradise San Blas island

2. Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
Narganá
SAR 7,526
SAR 8,294 total
includes taxes & fees
8 Sep - 9 Sep
Cocoloco - Catamaran Lagoon 52F SAN BLAS

3. Casa frente al mar - turtle cay marina

Casa frente al mar - turtle cay marina
Nombre de Dios
SAR 2,007
SAR 2,358 total
includes taxes & fees
31 Aug - 1 Sep
Casa frente al mar - turtle cay marina

4. Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
Narganá
United States
Ryan
SAR 706
SAR 777 total
includes taxes & fees
31 Aug - 1 Sep
Private Ocean-Front Cabin with private bathroom on San Blas Island
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkeling. Hike through lush rainforest trails to spot colorful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

See all hotels in Santa Isabel
A tropical island with a beach, clear turquoise waters, and lush greenery.

Top Santa Isabel Hotel Reviews

Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand

10/10 Excellent
"the view is beautiful! We were taken care of well."
Mirelys 5-night trip
Posted 1 month ago
Caribbean getaway: beach cottage just on the sand
Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent
"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "
Ryan 4-night trip
Posted 6 months ago
Private Ocean-Front Cabin with private bathroom on San Blas Island
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

10/10 Excellent
"This was an incredible stay with so many lovely preparation of meals from Lucy and Jose. They were helpful and so thoughtful. We rested, relaxed, and spent leisurely days being together as a family. If only this happened more often! What a great trip. I am sad it ended so soon. Thank you to a wonderful host, Leticia, who went above and beyond helpful. "
Dennis Or Trish H. 6-night trip
Posted 9 months ago
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

More cheap stays in Santa Isabel

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala
SAR 706
SAR 777 total
31 Aug - 1 Sep
includes taxes & fees
10/10 Exceptional! (1 review)
Private Ocean-Front Cabin with private bathroom on San Blas Island
Cabins on paradise San Blas island

Cabins on paradise San Blas island

9.587566, -78.879820 Narganá San Blas
SAR 1,010
SAR 1,111 total
31 Aug - 1 Sep
includes taxes & fees
Cabins on paradise San Blas island
Private wood Cabins on San Blas island - private bathroom

Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala
Get ratesPrivate wood Cabins on San Blas island - private bathroom
 Paradise Over the Water Cabins in San Blas

Paradise Over the Water Cabins in San Blas

G4V2 48 Narganá Guna Yala
Get rates
6/10 (1 review)
Paradise Over the Water Cabins in San Blas
Trips Guna Yala

Trips Guna Yala

Urgandi, Mamardub Narganá Guna Yala
Get ratesTrips Guna Yala
Hotel El Porvenir

Hotel El Porvenir

Isla Porvenir Narganá Guna Yala
Get ratesHotel El Porvenir

Find out more about Santa Isabel

Top reasons to visit Santa Isabel

  • Stunning Beaches: Santa Isabel boasts beautiful beaches with soft sand and crystal-clear waters, perfect for relaxation and fun.
  • Outdoor Adventures: The area offers hiking trails and eco-friendly destinations, making it ideal for outdoor enthusiasts.
  • Vibrant Culture: Immerse yourself in the local culture with authentic experiences and explore nearby neighborhoods.
  • Scenic Views: Enjoy captivating city views while strolling along the oceanfront, enhancing your vacation experience.
  • Diverse Accommodations: From cozy lodges to luxurious hotels, Santa Isabel has a range of options to suit every traveler.

Find great hotels near Santa Isabel

Explore a variety of hotel accommodations in Santa Isabel, Colón, Panama, ideal for your beach vacation. Whether you’re looking for a cozy lodge or a luxurious hotel, you’ll find options that cater to your needs. With numerous hotel reviews and a quick search for the best hotels in the area, you can easily plan your perfect getaway in this picturesque coastal destination.

  • Cabins on paradise San Blas island: Experience a tropical retreat at Cabins on Paradise San Blas Island, located 25.7km from Santa Isabel. This hotel-type lodging is perfect for those seeking a tranquil getaway. Guests can indulge in complimentary daily breakfast options, savor local delicacies, and enjoy snacks at the on-site restaurant. The inviting atmosphere and beautiful surroundings make it an ideal spot for relaxation and rejuvenation, ensuring an unforgettable vacation experience.
  • Cabañas Nalunega San Blas: Situated 27.4km from Santa Isabel, Cabañas Nalunega San Blas offers a cozy lodge experience for adventurous souls. Guests can enjoy dinner at the on-site restaurant and explore the local breakfast options available at a fee. With exciting activities like boat tours onsite, this lodge is perfect for travelers looking to immerse themselves in nature and create lasting memories. Enjoy the rustic charm and welcoming ambiance that this lodge has to offer.
  • Cabañas Isla Nubesidub San Blas: For those craving a beach vacation experience, Cabañas Isla Nubesidub San Blas is a perfect choice, located 27.4km from Santa Isabel. This lodge boasts direct access to stunning beaches, allowing guests to soak up the sun and embrace the coastal lifestyle. The property is ideal for beach lovers seeking relaxation and adventure. Enjoy the serene environment and the sound of waves, making it a place to unwind and connect with nature.

Where to stay near Santa Isabel

Santa Isabel, located on Panama's stunning southern coast, offers a perfect blend of beach and outdoor adventures. Stroll along the oceanfront, soak in captivating city views, and explore nearby eco-friendly destinations. Families will enjoy the charm of this strategic location, making it an ideal base for discovering the region's natural beauty and vibrant culture. Don't miss the chance to experience the essence of Old Havana in the surrounding neighborhoods, enhancing your unforgettable vacation.

  • Miramar: Nestled approximately 16.1km from Santa Isabel, Miramar is a charming city that attracts seasonal travelers seeking a delightful beach and outdoor experience. With peak visitor numbers from January to March, this coastal destination offers stunning views and a laid-back atmosphere. Visitors can explore nearby islands, perfect for a day of relaxation or adventure. Whether you're sunbathing on the beach or partaking in water activities, Miramar is a great spot to unwind and enjoy nature's beauty.
  • Palenque: Located about 19.3km from Santa Isabel, Palenque is a vibrant city that welcomes visitors year-round. With peak travel occurring between January and March, and slightly quieter months in May to June and November, Palenque is ideal for families and beach enthusiasts alike. The city boasts a variety of attractions, including shopping centers and resorts, and is surrounded by beautiful parks and research facilities. Whether you're indulging in retail therapy or enjoying a family day out in the sun, Palenque has something for everyone.
  • Carti: Situated around 25.7km from Santa Isabel, Carti is a quaint village known for its eco-friendly and outdoor experiences. With peak visitor traffic in April and the festive months of December and January, Carti is perfect for families looking to explore the natural wonders of the region. Visitors can enjoy picturesque beaches and the nearby national park, which offers stunning landscapes and opportunities for adventure. With shopping centers adding to your convenience, Carti is a hidden gem for those seeking tranquility and exploration.

Things to do near Santa Isabel

Santa Isabel, Colón, Panama, is a perfect destination for beach and outdoor vacations, offering various activities such as hiking trails and authentic local experiences. Visitors can enjoy outdoor seating at scenic spots, engage in numerous recreational activities, and unwind with spa treatments. Embrace the natural beauty and vibrant culture of this charming locale for a memorable getaway.

Shopping

In Santa Isabel, explore local shops for unique souvenirs. If you're up for a drive, visit Albrook Mall, about 45 minutes away, for a vast selection of stores and dining. For a more local experience, check out Mercado de Colón, where you can find handmade crafts and authentic Panamanian goods.

Recreation

The Serenity Spa offers rejuvenating treatments with organic ingredients, perfect for relaxation. Enjoy yoga classes on the beach, surrounded by the soothing sounds of waves. For adventure, explore the nearby rainforest, where guided hikes reveal vibrant wildlife and breathtaking views, ensuring a perfect balance of tranquility and excitement.

Adventure

Embark on the Honeycreeper Ridge Trail, located 33.8km from Santa Isabel, for an exhilarating hiking experience. Enjoy stunning scenery and immerse yourself in the great outdoors as you explore the adventurous vibes this trail has to offer.

Nightlife

Experience the vibrant nightlife at Moonlight Lounge, where you can enjoy exotic cocktails and dance to the latest beats. For a relaxed vibe, visit the Sunset Bar, offering stunning views and a selection of local beers to unwind after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Isabel

To save money on your vacation to Santa Isabel, visit during the cheaper months of January, March, or May, and book your hotel 1-3 months in advance for the best rates. Look for last-minute deals on Expedia, especially on Tuesdays, which are the cheapest days to stay. Utilize the site's filters to find eco-certified hotels and sort listings from lowest to highest price. Additionally, consider Expedia packages that combine hotels with flights and activities for greater savings. Enjoy free activities and explore the area on foot to minimize transportation costs.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Isabel are January, March and May, where the prices are slightly lower. This is in comparison to July and October to November, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel in Santa Isabel is usually 1-3 months out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Isabel is Tuesday. The most expensive day to stay in Santa Isabel is Wednesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your travel preferences, such as your budget, desired location, and type of hotel you’re looking for. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that are currently available. To find the best prices and deals, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel reservation in Santa Isabel with your flights and activities through an Expedia package.

Find the best attractions near Santa Isabel

Santa Isabel, Colón, Panama, is an ideal destination for beach and outdoor vacations, offering a variety of attractions such as national parks, museums, and rivers. Visitors can immerse themselves in the stunning scenery and rich culture, making it a perfect spot for outdoor enthusiasts. Don't miss the chance to explore Santa Isabel Island and nearby resorts, ensuring a memorable experience tailored to every traveler's interests.

  • Porvenir Museum: Located 22.5km from Santa Isabel, this museum offers a rich cultural experience showcasing indigenous art and history. Explore the vibrant exhibits that reflect the heritage of Panama's diverse communities.
  • Chagres National Park: Situated 30.6km away, this national park is a haven for outdoor lovers. Enjoy breathtaking scenery, hiking trails, and thrilling adventures amidst lush landscapes and diverse wildlife.
  • Mamoní River: Just 29.0km from Santa Isabel, the Mamoní River invites you to experience its stunning natural beauty. Perfect for kayaking and relaxing by the water, its serene environment offers a peaceful escape.

The nearest major airports for your trip to Santa Isabel

Traveling to Santa Isabel, Colón, Panama, is convenient via three major airports. Tocumen International Airport (PTY) is 56.3km away, with excellent hotel options such as The Santa Maria, a Luxury Collection Hotel, 8.0km from the airport, and JW Marriott Panama, 16.1km away. Marcos A. Gelabert International Airport (PAC) is 74.0km distant, featuring hotels like Sofitel Legend Casco Viejo, just 3.2km from the airport, and The Westin Playa Bonita Panama, 8.0km away. Balboa Panama Pacifico International Airport (BLB) is 82.1km from Santa Isabel, with Hilton Panama and Bristol Panama, both 9.7km away, offering shuttle services for easy access.

Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 17 mi (27.3 km) from the heart of Santa Isabel, Cocoloco - Catamaran Lagoon 52F SAN BLAS is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Private Ocean-Front Cabin with private bathroom on San Blas Island and Private wood Cabins on San Blas island - private bathroom. See all available top hotels, or vacation rentals in Santa Isabel.
What are some of the best vacation home rentals that Santa Isabel has to offer?
Casa frente al mar - turtle cay marina: This vacation home rental outside Santa Isabel is located in the suburbs and has a terrace, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a stovetop, a microwave, and kitchenware. See all vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
Where can I learn more about changing or cancelling my trip to Santa Isabel?
For additional details about rescheduling or cancelling your trip to Santa Isabel, go to https://www.expedia.com/service/.
What's the best place to stay near Tocumen International Airport (PTY)?
Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer including its parks. There are 40 hotels and other accommodations in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Chagres National Park and Porvenir Museum. Check out what more to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually June and September with an average temp of 80°F, while the coldest months are February and March with an average of 78°F. The rainiest months in Santa Isabel are October, August, July, and November, with each month seeing an average of 12 inches of rainfall.