Santa Isabel do Rio Negro Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to SARĀ 5,400 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santa Isabel do Rio Negro Vacation Packages

Santa Isabel do Rio Negro Hotel Deals

Hotel Express Vieiralves

Hotel Express Vieiralves

3 out of 5
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
The price is SARĀ 139 per night from Aug 21 to Aug 22
SARĀ 139
SARĀ 142 total
21 Aug - 22 Aug
includes taxes & fees
8.4/10 Very Good! (1,005 reviews)
"El hotel esta de acuerdo a la relaciĆ³n del precio"

Reviewed on 14 July 2026

Hotel Express Vieiralves
Tropical Executive Hotel

Tropical Executive Hotel

3 out of 5
Av. Coronel Teixeira 1320 A Manaus AM
Fully refundableReserve now, pay when you stay
The price is SARĀ 341 per night from Aug 1 to Aug 2
SARĀ 341
SARĀ 382 total
1 Aug - 2 Aug
includes taxes & fees
8.4/10 Very Good! (534 reviews)
"Hotel got an excellent location. Gate to access is only one way out with people coming in and out . Traffic becomes jammed . Room door couldnā€™t lock . Even when I try harder. So only card lock . Room as clear. And good. Internet was good too. I travel a lot and any hotel in US or Europe they serve ..."

Reviewed on 15 July 2026

Tropical Executive Hotel
Quality Hotel Manaus

Quality Hotel Manaus

3.5 out of 5
Avenida Mario Ypiranga, 1090 Manaus Amazonas
Fully refundableReserve now, pay when you stay
The price is SARĀ 409 per night from Aug 15 to Aug 16
SARĀ 409
SARĀ 459 total
15 Aug - 16 Aug
includes taxes & fees
Quality Hotel Manaus
See all 292 properties in Amazonas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Isabel do Rio Negro attractions

Pico da Neblina

Commune with nature and explore the great outdoors at Pico da Neblina during your travels in Santa Isabel do Rio Negro. Discover the mountain views while you're in the area.
See properties

Frequently asked questions

How much does a Santa Isabel do Rio Negro vacation package cost?
You can grab a vacation package to this destination on Expedia. But how much your vacation to Santa Isabel do Rio Negro costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Isabel do Rio Negro?
March, April and May are the best times to search for cheap Santa Isabel do Rio Negro vacation packages. Opting to travel in quieter months means you can typically find reduced prices on accommodations and flights.
How to find the best Santa Isabel do Rio Negro package deals?
Use Expedia's filter tool to help you find some of the best Santa Isabel do Rio Negro package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or search for Santa Isabel do Rio Negro package deals in the low season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a Santa Isabel do Rio Negro vacation as a package?
You can enjoy significant savings on your next Santa Isabel do Rio Negro getaway by booking a customized vacation package. Check the "Package" heading, then enter your destination and travel dates to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Santa Isabel do Rio Negro?
If you're planning a spur-of-the-moment Santa Isabel do Rio Negro trip, browse our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can score incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to Santa Isabel do Rio Negro?

  1. Choose the best time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to visit Santa Isabel do Rio Negro.
  2. Plan your budget wisely: Besides the price of your hotel, you should factor in other expenses. These include transportation, food and flights. Also, put aside a little extra for unexpected expenses that may crop up during your trip to Santa Isabel do Rio Negro.
  3. Decide how long to go away for: Now that you're up to speed on Santa Isabel do Rio Negro, you can work out the ideal length of your vacation. Pull together a rough itinerary and allocate enough time for all the things you want to do.
  4. Bundle your bookings: With your travel dates in order, you can combine your flights, hotels, car rental and more into a tailored Santa Isabel do Rio Negro vacation package.