The Best Hotels Closest to Santa Fe River in for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Santa Fe River hotels

A hotel with a covered entrance, stone facade, and blue lighting accents.

A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.

A modern office space with a reception desk, several chairs, a large window, and a colorful abstract painting on the wall.

A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

17.6 km from Santa Fe River

Austin

SAR 390

SAR 439 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

A hotel room with two beds, a desk, a chair, a TV, and a couch.

2. Hampton Inn & Suites Alachua I-75

18 km from Santa Fe River

Pamela

SAR 380

SAR 427 total

includes taxes & fees

15 Nov - 16 Nov

A cabin with a cozy interior, a dining area, and a view of the forest.

A bedroom with a wooden headboard, a bed with white linens, a window with a view of green foliage, and a tray with breakfast items.

A cozy cabin interior with a wooden interior, a dining table with a chair, a window, and a hanging lantern.

3. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

8.3 km from Santa Fe River

Katie

SAR 412

SAR 783 total

includes taxes & fees

3 Nov - 4 Nov

A stone water feature with cascading water, surrounded by a brick wall and greenery.

A spacious living area with a wooden floor, a blue sofa, a round coffee table, and a ceiling fan.

A covered outdoor area with a paved walkway leading to a seating area, surrounded by greenery and a clear sky.

A reception desk with a modern design, a ceiling fan, and a seating area with chairs and a table.

4. BlueGem Motel

9.6 km from Santa Fe River

Myra

SAR 359

SAR 404 total

includes taxes & fees

28 Oct - 29 Oct

A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.

A narrow kitchen with a wooden ceiling, a green refrigerator, and a wooden countertop.

A kitchen with a green refrigerator, a wooden countertop, a black kettle, and a wooden cutting board.

5. Vista Verde Farm Retreat

17.1 km from Santa Fe River

Stacy

SAR 489

SAR 715 total

includes taxes & fees

3 Nov - 4 Nov

A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.

A modern bathroom with a bathtub, toilet, and a shower area.

A bedroom with a bed, a chair, a dresser, a ceiling fan, a window with blinds, and a wall-mounted air conditioner.

A stone outdoor seating area with a table and benches, a trash bin, and a building in the background.

6. High Springs Country Inn

9.4 km from Santa Fe River

Paige

SAR 276

SAR 311 total

includes taxes & fees

25 Nov - 26 Nov

A swimming pool with a metal ladder, surrounded by a white fence and green chairs.

A living room with a curved sofa, a wooden cabinet, and a fish tank.

A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.

A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

7. Best Western Waldo Inn and Suites

51.2 km from Santa Fe River

Sarah

SAR 316

SAR 355 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a large bed, a desk, a chair, and a TV.

A motel with a covered entrance, multiple parking spaces, and a fire extinguisher on the wall.

A modern hotel lobby with a reception desk, seating area, and a wall-mounted television.

A modern hotel room with a wooden desk, a black office chair, a flat-screen TV mounted above the desk, and a coffee machine on the desk.

8. Clarion Pointe Alachua - Gainesville Area

18.7 km from Santa Fe River

Josey

SAR 226

SAR 273 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.

A corner room with two checkered chairs, a small table, a framed picture on the wall, and a floor lamp.

A bathroom with a large mirror, a sink, and a towel rack.

A building with a Coca-Cola vending machine, a window with a 'OPEN' sign, and a red awning.

9. Palms Garden Inn

20.3 km from Santa Fe River

Igor

SAR 241

SAR 271 total

includes taxes & fees

25 Nov - 26 Nov

A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.

A swimming pool with lounge chairs and umbrellas, a covered seating area, and a multi-story building with balconies.

A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

A hotel room with a bed, a desk with a chair, a television, a mirror, and a wardrobe.

10. Quality Inn Alachua - Gainesville Area

18.6 km from Santa Fe River

Ivelisse

SAR 273

SAR 307 total

includes taxes & fees

15 Nov - 16 Nov

A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.

A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.

A hotel room with two beds, a TV, a desk, and a chair.

11. Holiday Inn Express Starke by IHG

56.4 km from Santa Fe River

Judy

SAR 402

SAR 446 total

includes taxes & fees

22 Nov - 23 Nov

A hotel room with two beds, a desk, a chair, and a television.

A large, empty parking lot with marked parking spaces and a few trees in the background.

A parking lot with marked lanes and a grassy area on one side.

A bathroom with a white sink, mirror, and towel rack.

12. Royal Inn

17.9 km from Santa Fe River

James

SAR 232

SAR 261 total

includes taxes & fees

24 Nov - 25 Nov

A hotel room with a bed, bedside lamps, a nightstand, a mirror, a bathroom with a sink and a bathtub.

A rectangular pool with a depth of 3 feet 2 inches, surrounded by a white fence and a building with a red roof in the background.

A motel with a sign for 'America's Best Value by Vantage Inn'.

A bathroom with a bathtub, a sink, and a mirror.

13. Americas Best Value Inn Starke

58.4 km from Santa Fe River

Andy

SAR 282

SAR 312 total

includes taxes & fees

26 Oct - 27 Oct

A swimming pool with a white fence, palm trees, and a building with balconies in the background.

A hotel corridor with a covered balcony, palm trees, and a lawn.

A hotel room with two beds, orange walls, a window with curtains, and a door with a lock.

A hotel reception area with a modern design, featuring a reception desk, a coffee station, and a view of the outdoors.

14. Motel 6 Starke, FL

58.5 km from Santa Fe River

Carol

SAR 209

SAR 232 total

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, a bathroom with a sink and mirror, and a view of the outdoors.

A hotel room with a bed, a bathroom with a sink and mirror, a wooden chair, and a television.

A motel with a parking lot, a staircase leading to the entrance, and a large tree in front.

A reception area with a desk, chairs, a clock, and a bulletin board.

15. Travelers Inn

38.8 km from Santa Fe River

Joseph

SAR 244

SAR 274 total

includes taxes & fees

26 Oct - 27 Oct

A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

A dining area with a round wooden table, four chairs, and a window with curtains.

A living room with a fireplace, a ceiling fan, a television, and a sofa.

A kitchen with wooden cabinets, a central island, a stove, and a microwave.

16. < 1 Mi From Suwannee River, Hideaway w/ Lanai

23.3 km from Santa Fe River

Karen

SAR 540

SAR 1,453 total

includes taxes & fees

26 Oct - 27 Oct

A gazebo with a tiled roof, surrounded by stone pillars and palm trees.

A modern hotel room with a large bed, bedside tables, a desk, and a mirror.

A reception area with a modern design, featuring a reception desk, a blue patterned wall, and a glass door leading outside.

A conference room with two desks, two chairs, and two monitors.

17. Best Western Starke

58.7 km from Santa Fe River

Lonnie

SAR 390

SAR 433 total

includes taxes & fees

26 Oct - 27 Oct

A compact hotel room with a kitchenette, a dining area, a sofa, and large windows.

A reception area with a counter, a computer, a fan, and a registration sign.

A building with a sloped roof, a covered entrance, and a fountain in the foreground.

A room with a desk, a computer, a fan, and various potted plants.

18. Campus Inn by Hotel O Gainesville - University Area

38.8 km from Santa Fe River

Cristian

SAR 218

SAR 252 total

includes taxes & fees

26 Oct - 27 Oct

A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.

A hotel room with two beds, a bedside table with a lamp, and a painting on the wall.

A hotel room with a wooden headboard, a colorful striped bedspread, two bedside lamps, a framed picture on the wall, and a small bedside table with a phone.

A single-story motel with a red roof and beige walls. It features a covered front porch and a small parking area.

19. Red Carpet Inn

58.3 km from Santa Fe River

david

SAR 259

SAR 287 total

includes taxes & fees

26 Oct - 27 Oct

A hotel room with a large bed, two bedside tables, a nightstand, a painting on the wall, and a window with a curtain.

A hotel room with two beds, a desk, and a chair.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A hotel room with a large bed, a nightstand, a lamp, a painting on the wall, and a window with curtains.

20. Americas Best Value Inn Alachua

17.9 km from Santa Fe River

Jennifer

View all properties

Compare popular hotels close to Santa Fe River

Property	Property class	Guest rating
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG	9.4 Exceptional 1,002 reviews	View
Hampton Inn & Suites Alachua I-75	9.4 Exceptional 570 reviews	View
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy	10.0 Exceptional 292 reviews	View
BlueGem Motel	9.2 Wonderful 483 reviews	View
Vista Verde Farm Retreat	9.8 Exceptional 21 reviews	View

Top Santa Fe River Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent

"What a lovely hotel! Very fresh and clean. The room was excellent. I especially liked the generous surface space to spread out any items you want to be able to get to quickly. Dove products in the bathroom. We ate our yummy breakfast in the outdoor patio next to the pool in the dazzling morning sunshine. Lastly, every single staff member was so kind. We were impressed. Highly recommend."

High Springs Country Inn

10/10 Excellent

"The staff was very nice and friendly. The room had been newly renovated and was clean. The neighboring room was still being renovated when we checked in so there was some construction going on but not in the evenings. Overall it was a nice place to stay."

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Bed is extremely comfortable! All the amenities were 10/10!"

Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee

10/10 Excellent

"The view is worth it! And of course, the kayaks and the ability to get on the water so easily without leaving the property. I loved the wrap around deck and the clean, updated interior. A small gem."

Rum Island Oasis - Springs Getaway!

10/10 Excellent

"Property was clean, cute and in a great location to multiple springs."

The Rustic River Retreat at Ginnie Springs

10/10 Excellent

"Overall the house was spot on to what the pictures presented. The host is easy to deal with and when something was amiss they were there. My family enjoyed their stay and the dog friendly part was spot on!! Thank you Natasha. We look forward to spending some time there again in the near future."

Charming Santa Fe River Cottage - 10-15 min from 3 of FLA's most popular springs

10/10 Excellent

"This is convenient to the river and the county activities. We enjoyed our stay in this sweet house. Mornings and evenings on the screen porch were particularly fine. The clear communication, the clean house and the well ordered set up were appreciated. A lovely time."

Cozy 1-bedroom camper in nice High Springs with AC

8/10 Good

"The camper trailer was clean and as pictured. We stayed for 2 days of the 3 days we had planned for but needed to leave 1 day early . The hosts we very accommodating by providing a portable Air conditioner due to the extreme heat during our visit. Infortunately we found out that the clear springs that we came to visit were closed as they had dried up!"

Sunny Riverfront Cottage - on a Farm close to the Springs!

10/10 Excellent

"Property was beautiful and amazing."

Other attractions near Santa Fe River

An underwater scene with rocky formations and clear water.

Ginnie Spring

8.6/10 (51 reviews)

Commune with nature and explore the great outdoors at Ginnie Spring during your travels in High Springs. Amble around the area's parks or visit its shops.

See properties

A clear blue lake surrounded by a forest with a wooden bridge.

Ruth B. Kirby Gilchrist Blue Springs State Park

9.4/10 (52 reviews)

You can take time to visit Ruth B. Kirby Gilchrist Blue Springs State Park during your travels to High Springs. Discover the area's restaurants or seek out the kayaking spots.

See properties

Ichetucknee Conservation Area

You can take time to visit Ichetucknee Conservation Area during your travels to Branford. Make some time to visit the shops while you're in the area.

See properties

McCall Park

Explore the great outdoors at McCall Park, a lovely green space in High Springs. Amble around the area's parks or visit its shops.

See properties

Columbia Rise

Commune with nature and explore the great outdoors at Columbia Rise during your travels in High Springs. Amble around the area's parks or visit its shops.

See properties

High Springs Library Branch

High Springs Library Branch is just one of the places to see in High Springs, so why not enjoy the other things to explore during your travels? Amble around the area's parks or visit its shops.

See properties

High Springs Museum

You can spend an afternoon browsing the exhibits at High Springs Museum during your travels in High Springs. Amble around the area's parks or visit its shops.

See properties

Frequently asked questions

What's the area like around Santa Fe River?

If you're planning to come to the area to visit Santa Fe River, take some time to see the rest of the sights while you're in town. This family-friendly area is known for its array of dining options and sporting events. You'll find 31 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay near Santa Fe River?

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy is one of the top choices for your stay based on our traveler data, and this cabin offers free parking and private patios. You'll find it 5.2 mi (8.3 km) from Santa Fe River. Other good choices around the area include Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and BlueGem Motel.

How many hotels are there close to Santa Fe River?

Expedia has 31 hotels and other accommodations a few miles from Santa Fe River.

If I need to cancel the hotel reservation for my stay near Santa Fe River, will I receive a refund?

Yes, the majority of room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best options available near Santa Fe River.

Where can I learn more about changing or cancelling my trip in the area near Santa Fe River?

To find more details about updating your stay near Santa Fe River or cancelling it, go to https://www.expedia.com/service/.

Find hotels near Santa Fe River, from SAR 232

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe River hotels

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

2. Hampton Inn & Suites Alachua I-75

3. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

4. BlueGem Motel

5. Vista Verde Farm Retreat

6. High Springs Country Inn

7. Best Western Waldo Inn and Suites

8. Clarion Pointe Alachua - Gainesville Area

9. Palms Garden Inn

10. Quality Inn Alachua - Gainesville Area

11. Holiday Inn Express Starke by IHG

12. Royal Inn

13. Americas Best Value Inn Starke

14. Motel 6 Starke, FL

15. Travelers Inn

16. < 1 Mi From Suwannee River, Hideaway w/ Lanai

17. Best Western Starke

18. Campus Inn by Hotel O Gainesville - University Area

19. Red Carpet Inn

20. Americas Best Value Inn Alachua

Compare popular hotels close to Santa Fe River

Top Santa Fe River Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

High Springs Country Inn

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Santa Fe River Front, Luxury Retreat near Ginnie Springs and Ichetucknee

Rum Island Oasis - Springs Getaway!

The Rustic River Retreat at Ginnie Springs

Charming Santa Fe River Cottage - 10-15 min from 3 of FLA's most popular springs

Cozy 1-bedroom camper in nice High Springs with AC

Sunny Riverfront Cottage - on a Farm close to the Springs!

Other attractions near Santa Fe River

Ginnie Spring

Ruth B. Kirby Gilchrist Blue Springs State Park

Ichetucknee Conservation Area

McCall Park

Columbia Rise

High Springs Library Branch

High Springs Museum

Frequently asked questions