Santa Cruz Vacations

Book a Hotel + Flight together to unlock savings

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  • Better together

    Save up to SARĀ 5,400 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is SARĀ 403 per night from Jul 12 to Jul 13
SARĀ 403
SARĀ 403 total
12 Jul - 13 Jul
Santa Cruz Plaza
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, CapellanĆ­a Santa Cruz O'Higgins
The price is SARĀ 331 per night from Jun 25 to Jun 26
SARĀ 331
SARĀ 331 total
25 Jun - 26 Jun
La Perla Hotel
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is SARĀ 313 per night from Jul 19 to Jul 20
SARĀ 313
SARĀ 313 total
19 Jul - 20 Jul
9.6/10 Exceptional! (85 reviews)
""I had a wonderful experience at this hotel. The location is fantastic—central and convenient to everything I wanted to see. The room was spotless and well-maintained, which I really appreciated. But what truly sets this place apart is the staff. From the front desk to the housekeeping team, everyone ..."

Reviewed on 1 April 2026

Hotel Vendimia Parador
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How do I find cheap flights to Santa Cruz that have flexible change policies?
It's quick and easy with Expedia. Firstly, enter your travel dates and destination and click on "Search." Step 2: Check "No change fee" directly below the "Flexible change policies" heading on the left-hand side of your screen. Step 3. Snag a cheap and flexible airfare to Santa Cruz.
Which airlines fly to Santa Cruz?
Take your pick of these two top carriers that operate flights to or near Santa Cruz:

  • LATAM Airlines - 121 flights to or near Santa Cruz each month, including 121 flights to Arturo Merino Benitez Airport (SCL) per month.
  • American Airlines - 30 flights to or near Santa Cruz each month, including 30 flights to Arturo Merino Benitez Airport (SCL) per month.

How can I find cheap tickets to Santa Cruz?
In the last seven days, was the best price for a flight to Santa Cruz. For an even cheaper fare, book in advance and be flexible with your travel dates. Search for your flight to Santa Cruz, then compare prices for nearby days by clicking on our "flexible dates" link.
How much is a flight to Santa Cruz?
The cost of a round-trip journey to Santa Cruz in the last seven days fluctuated between and . If you were traveling one way from (), you could have scored a low-cost fare from only .
What are the most popular airports to fly into in Santa Cruz?
Book your flight to Arturo Merino Benitez Airport (SCL) and experience everything that Santa Cruz has to offer. As the region's main point of entry, around 151 flights touch down here every month.
When is the cheapest time to fly to Santa Cruz?
Depart for Santa Cruz early on in the week and you'll usually be rewarded with lower fares. Tuesday is typically the cheapest day to fly out, with Monday a close second. If you're hoping to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Santa Cruz?
In the last seven days, flights to Santa Cruz varied between and . Prices depend on the departure time, airline, cabin class and when the fare is booked.
What months are the cheapest to book a flight to Santa Cruz?
Snap up your ticket in February to unlock inexpensive flights to Santa Cruz. December is often the most expensive time to purchase an airfare.
How long is a flight to Santa Cruz?
Here are a few of the most popular services to Santa Cruz along with their average travel times. Bring a book or magazine to make your flight whiz by:

  • Miami, FL (MIA-Miami Intl.) to Arturo Merino Benitez Airport (SCL) - 8 hours and 15 minutes
  • New York, NY (JFK-John F. Kennedy Intl.) to Arturo Merino Benitez Airport (SCL) - 10 hours and 30 minutes
  • Los Angeles, CA (LAX-Los Angeles Intl.) to Arturo Merino Benitez Airport (SCL) - 10 hours and 45 minutes