Santa Cruz Vacations

Book a Hotel + Flight together to unlock savings

Photo by Vivian Rennó

  • Plan, book, travel with confidence

  • Better together

    Save up to SAR 390 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is SAR 488 per night from Jan 13 to Jan 14
SAR 488
SAR 488 total
13 Jan - 14 Jan
8.6/10 Excellent! (337 reviews)
Yes all great.

Reviewed on 11 December 2025

Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (171 reviews)
Hermosa localidad y buen servicio.

Reviewed on 24 October 2025

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Hotel Cava Colchagua
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
The price is SAR 608 per night from Jan 13 to Jan 14
SAR 608
SAR 608 total
13 Jan - 14 Jan
9/10 Wonderful! (206 reviews)
Clean and spacious suite, fantastic staff and service and very picturesque location

Reviewed on 22 December 2025

TerraViña
See all 57 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

Lapostolle Clos Apalta Winery

You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Lapostolle Clos Apalta Winery

Casino Colchagua

Why not roll the dice with a visit to Casino Colchagua during your visit to Santa Cruz? While in this relaxing area, you can savor the wineries and restaurants.

Casino Colchagua

Museo de Colchagua

You can spend time exploring the galleries in Museo de Colchagua during your trip to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Museo de Colchagua

Frequently asked questions

How do I find cheap flights to Santa Cruz that have flexible change policies?
It's quick and easy with Expedia. Firstly, enter your travel dates and destination and click on "Search." Step 2: Check "No change fee" directly below the "Flexible change policies" heading on the left-hand side of your screen. Step 3. Snag a cheap and flexible airfare to Santa Cruz.
Which airlines fly to Santa Cruz?
Take your pick of these two top carriers that operate flights to or near Santa Cruz:

  • LATAM Airlines - 121 flights to or near Santa Cruz each month, including 121 flights to Arturo Merino Benitez Airport (SCL) per month.
  • American Airlines - 30 flights to or near Santa Cruz each month, including 30 flights to Arturo Merino Benitez Airport (SCL) per month.

How can I find cheap tickets to Santa Cruz?
In the last seven days, was the best price for a flight to Santa Cruz. For an even cheaper fare, book in advance and be flexible with your travel dates. Search for your flight to Santa Cruz, then compare prices for nearby days by clicking on our "flexible dates" link.
How much is a flight to Santa Cruz?
The cost of a round-trip journey to Santa Cruz in the last seven days fluctuated between and . If you were traveling one way from (), you could have scored a low-cost fare from only .
What are the most popular airports to fly into in Santa Cruz?
Book your flight to Arturo Merino Benitez Airport (SCL) and experience everything that Santa Cruz has to offer. As the region's main point of entry, around 151 flights touch down here every month.
When is the cheapest time to fly to Santa Cruz?
Depart for Santa Cruz early on in the week and you'll usually be rewarded with lower fares. Tuesday is typically the cheapest day to fly out, with Monday a close second. If you're hoping to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Santa Cruz?
In the last seven days, flights to Santa Cruz varied between and . Prices depend on the departure time, airline, cabin class and when the fare is booked.
What months are the cheapest to book a flight to Santa Cruz?
Snap up your ticket in February to unlock inexpensive flights to Santa Cruz. December is often the most expensive time to purchase an airfare.
How long is a flight to Santa Cruz?
Here are a few of the most popular services to Santa Cruz along with their average travel times. Bring a book or magazine to make your flight whiz by:

  • Miami, FL (MIA-Miami Intl.) to Arturo Merino Benitez Airport (SCL) - 8 hours and 15 minutes
  • New York, NY (JFK-John F. Kennedy Intl.) to Arturo Merino Benitez Airport (SCL) - 10 hours and 30 minutes
  • Los Angeles, CA (LAX-Los Angeles Intl.) to Arturo Merino Benitez Airport (SCL) - 10 hours and 45 minutes