Vacation Homes in Panama

Compare and save

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Top Cities in Panama

Vacation Homes in Panama

Our top choices for Panama vacation homes

Beach House with Ocean View - Rooftop Jacuzzi & Pool - Concierge Service

10.0 out of 10, Exceptional, (38)
"Great place to stay. Host is very responsive. Short walk to beach. Great views from rooftop pool area. Overall excellent. "
Beach House with Ocean View - Rooftop Jacuzzi & Pool - Concierge Service

Oasis with pool near panama canal

9.4 out of 10, Exceptional, (22)
"Nice neighborhood nice pool ."
The price is SAR 713
SAR 1,020 total
includes taxes & fees
16 Sep - 17 Sep
Oasis with pool near panama canal

Directly on beach in Buenaventura, huge home with private pool, perfect vacation

10.0 out of 10, Exceptional, (1)
"Amazing holiday ! Everything and everyone were brilliant! Thank you "
Directly on beach in Buenaventura, huge home with private pool, perfect vacation

Panama View House – A Hilltop Retreat with Stunning Canal Views

The price is SAR 135
SAR 360 total
includes taxes & fees
16 Sep - 17 Sep
Panama View House – A Hilltop Retreat with Stunning Canal Views

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

2.0 star property
10.0 out of 10, Exceptional, (4)
"We had a wonderful stay at the classic home in Ancon. Lot’s of room to spread out and convenient location to attend a milestone birthday party in the city. Would definitely recommend for a family gathering and the host was very attentive!"
Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces

Casita del Mar, Bocas del Toro, Panama

10.0 out of 10, Exceptional, (59)
"A perfect combination of private accommodations with access to a personal captain to travel to some of the amazing places the area has to offer. Plenty of wildlife including: Dolphins, starfish, sloths, monkeys, geckos, many types of fish and birds. Access to the kayaks and paddleboards was great too. Amazing how calm the water was a certain times of the day. "
Casita del Mar, Bocas del Toro, Panama

LILIA HOUSE 10 MINUTES AIRPORT

The price is SAR 135
SAR 240 total
includes taxes & fees
29 Sep - 30 Sep
LILIA HOUSE 10 MINUTES AIRPORT

Large calm house surrounded by nature

2.0 star property
Large calm house surrounded by nature

Private Villa at Red Frog Beach Resort

10.0 out of 10, Exceptional, (7)
"What a wonderful property and the host is such a great communicator, making preparation and staying there easy. I'd recommend getting food/drink/water supplies on the main island before coming over as the local store is good but is sometimes out of a few things "
Private Villa at Red Frog Beach Resort

Private Oceanfront 4 Bedroom Villa -Pool & on Beach

10.0 out of 10, Exceptional, (5)
"It was a wonderful experience. Everything about our stay exceeded our expectations. Ms. Ashley was very prompt in replying to my inquiries and made all the arrangements to pick us up from the airport and transfer us to her property. This house has an amazing view and it is a very well maintained property. Red Frog Beach Resort staff was very courteous. Overall this was a wonderful experience."
Private Oceanfront 4 Bedroom Villa -Pool & on Beach

House in Boquete with king beds and hot tub

10.0 out of 10, Exceptional, (3)
"."
The price is SAR 1,313
SAR 1,865 total
includes taxes & fees
24 Sep - 25 Sep
House in Boquete with king beds and hot tub

House in Punta Paitilla B19

10.0 out of 10, Exceptional, (6)
"we had a blast and enjoyed it, it was well taken care of an in a great location"
House in Punta Paitilla B19

BirdHouse@Gamboa, Panama Canal

9.6 out of 10, Exceptional, (22)
"One of a kind home with a character and design unlike any other we’ve seen. It was a memorable stay with lovely times in the pool listening to the howler monkeys in the nearby hills We had the added benefit of getting to know the property owner Chimene. Thank you! Team Canada"
BirdHouse@Gamboa, Panama Canal

Boquete Panama CV3 Walk to town, views, river, gardens and bird watching

6.0 out of 10, (1)
"Very nice spacious unit. Large kitchen sitting area and good sized bedroom. Unit was not very clean on arrival. Wife found a dead frog under in living room and many of the dishes and counters needed cleaning before could be use. Heavy rains caused flooding in unit which was mopped up first time by owner. Second time by us. Owner or host could have been around more for short term stays to be a source of information and solve issues like turning on back up water when city water has been down for 6...
Boquete Panama CV3 Walk to town, views, river, gardens and bird watching

Alojamiento Entero Para Familia en Coronado, Casa Ideal [ Apta Para Mascotas.]

Alojamiento Entero Para Familia en Coronado, Casa Ideal [ Apta Para Mascotas.]

Mariposa Blanca Playa Lajas Large Modern Beach House

10.0 out of 10, Exceptional, (4)
"It was a beautiful home in the middle of nowhere. It is an 1 hour flight from Panama City and about an hour drive from Airport David. Once you are there it is so peaceful and self contained. Right on the beach of the Pacific Ocean and a cute little beach club down the road. Great set up for BBQ and swimming in the pool. Perfect for a quiet getaway with family. The host was helpful and quick to respond. My boys learned how to surf here."
Mariposa Blanca Playa Lajas Large Modern Beach House

Romantic Getaway: Luxury 1-Bedroom in Gated Community of Punta Chame Resort

10.0 out of 10, Exceptional, (4)
"We thoroughly enjoyed our one-month stay in Panama at Punta Chame Club and Beach Resort! One of the best vacations both of us have ever experienced!! Our hosts, Deborah and Wayne, were amazing. So helpful at giving great advice every step of our trip, from the time we first booked our stay one year before the trip, to the end of our one-month stay at their lovely 10-home gated property. Very friendly atmosphere; gorgeous pool, which I took advantage of twice a day; great music; and fun...
Romantic Getaway: Luxury 1-Bedroom in Gated Community of Punta Chame Resort

Casa de Campo Mia

2.5 star property
8.6 out of 10, Excellent, (18)
"Excellent stay, Owners on property. Very accommodating. "
Casa de Campo Mia

Modern, Tranquil Beachfront House with Garden

10.0 out of 10, Exceptional, (1)
"Alex, the property manager was fantastic. I recommend getting What’s App and he will be very responsive. He lives upstairs. There are 3 bedrooms with 3 baths. 2 of the baths are down an outdoor breezeway but very close. Great patio area. BBS Bar next door has great good food and is over the ocean, wonderful! Good beach close. Walk around island is interesting as you get to see the locals who are very friendly. Bring bug spray!"
Modern, Tranquil Beachfront House with Garden

Breathtaking Views Mansion w/King Beds

10.0 out of 10, Exceptional, (4)
"Great location, quiet neighborhood!"
Breathtaking Views Mansion w/King Beds
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews