Vacation Homes in Orangeburg County

Compare and save

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
11 Jul - 13 Jul
In two weeks
18 Jul - 20 Jul
In one month
1 Aug - 3 Aug
In two months
29 Aug - 31 Aug

Top Cities in Orangeburg County

Claflin University, located in Orangeburg, South Carolina, was founded in 1869 by Alonzo Webster (1818-1887), a Vermont minister. Webster came to South Carolina to teach at the Baker Bible Institute in Charleston training African American ministers for the Methodist Episcopal Church (today the United Methodist Church). In 1869 he received a charter from the state of South Carolina to establish a college that would prepare freed slaves for the responsibilities of citizenship. The first charter banned discrimination among the faculty, staff and students, making the Academy the first South Carolina university open to all regardless of race. Nonetheless, all of the students at the Academy were African American.
Vacation HomesVacation Homes

Orangeburg

Orangeburg

Compare 202 Vacation Homes in Orangeburg County with updated reviews, rates, and availability.

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Marina

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.8 out of 10, Exceptional, (234)
"great place for a fishing trip in february"
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Jewel on the Lake - Relaxing Lakefront Home
Game room

Jewel on the Lake - Relaxing Lakefront Home

9.6 out of 10, Exceptional, (26)
"Enjoyed the Lake. Neighbors dogs barked the entire time we were on property."
Jewel on the Lake - Relaxing Lakefront Home
LAKE MARION LAKE FRONT VACATION RENTAL
Terrace/patio

LAKE MARION LAKE FRONT VACATION RENTAL

9.4 out of 10, Exceptional, (87)
"Very good "
LAKE MARION LAKE FRONT VACATION RENTAL
Lake Marion Getaway!
TV

Lake Marion Getaway!

2.0 star property
9.2 out of 10, Wonderful, (38)
"Very nice host. Place was clean and had plenty of room. Family enjoyed their stay. "
Lake Marion Getaway!
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Fridge, microwave, oven, stovetop

6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates

6.8 out of 10, (9)
"Wonderful place to stay with a group. Rustic but has everything you need. Very comfortable. "
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Miscellaneous

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

10.0 out of 10, Exceptional, (148)
"This place was amazing. It was my husband and his friend that stayed for a fishing tournament. Plenty of boat parking, very helpful owners, super clean and spacious. It was their favorite place that they have ever stayed. "
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Life is better at the Lake Lakefront home that sleeps 13!
Beach

Life is better at the Lake Lakefront home that sleeps 13!

9.6 out of 10, Exceptional, (9)
"Our stay was excellent! Morgan was super helpful and very friendly. Views were gorgeous! 10 out of 10 recommend! "
Life is better at the Lake Lakefront home that sleeps 13!
Deep Water Lakefront Home w/ Private Dock
Beach

Deep Water Lakefront Home w/ Private Dock

9.8 out of 10, Exceptional, (14)
"We really enjoyed our stay, beautiful view of the lake. The house was equipped with everything we needed for our stay and is very nicely decorated."
Deep Water Lakefront Home w/ Private Dock
Archie's Lake Daze Cottage
Property grounds

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (72)
"Archie’s Lake Daze cottage was everything we expected and more! We will definitely book again."
Archie's Lake Daze Cottage
Hopper · CHAS, SUMMRVLL/NEXTON Comfort Near Everything!
Fridge, microwave, oven, stovetop

Hopper · CHAS, SUMMRVLL/NEXTON Comfort Near Everything!

9.8 out of 10, Exceptional, (33)
"Very clean and comfortable accommodations for our quick trip to visit family. Would definitely stay there again! "
Hopper · CHAS, SUMMRVLL/NEXTON Comfort Near Everything!
ENTIRE ENJOYABLE HOUSE WITH PLAY BOARDS IN SUMMERVILLE <br>5BEDROOM
Fridge, microwave, oven, stovetop

ENTIRE ENJOYABLE HOUSE WITH PLAY BOARDS IN SUMMERVILLE <br>5BEDROOM

9.4 out of 10, Exceptional, (29)
"This home was perfect for extended family while in town for a reunion - clean, comfortable and fun!"
The price is SAR 574
SAR 1,604 total
includes taxes & fees
11 Jul - 12 Jul
ENTIRE ENJOYABLE HOUSE WITH PLAY BOARDS IN SUMMERVILLE <br>5BEDROOM
Relax at the Lakehouse with a Dock
Fridge, microwave, oven, stovetop

Relax at the Lakehouse with a Dock

10.0 out of 10, Exceptional, (44)
"This little lake house was wonderful. We really enjoyed our family getaway."
Relax at the Lakehouse with a Dock
Home away from home. Close to everything Aiken SC
Fridge, microwave, oven, stovetop

Home away from home. Close to everything Aiken SC

10.0 out of 10, Exceptional, (2)
"We enjoyed our stay in Aiken. The property was well maintained and clean, and the host was very responsive!"
Home away from home. Close to everything Aiken SC
3-bedroom house in beautiful country setting with AC and WiFi.Gorgeous old oaks.
Fridge, microwave, oven, stovetop

3-bedroom house in beautiful country setting with AC and WiFi.Gorgeous old oaks.

2.0 star property
10.0 out of 10, Exceptional, (1)
"It was just an overall wonderful experience!!!!"
3-bedroom house in beautiful country setting with AC and WiFi.Gorgeous old oaks.
Lake Marion Lakehouse with 180° lake view
Beach

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (62)
"Clean family friendly place to stay and a nice neighbor hood."
Lake Marion Lakehouse with 180° lake view
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Property grounds

Golf and Lake fun on Santee! Bring your boat or golf clubs!

9.6 out of 10, Exceptional, (29)
"This is a very nice home, very clean and the host is the greatest. Robert was very flexible with my constant change in the itinerary, as my stay was extended three times. I’m looking forward to my next visit. "
The price is SAR 422
SAR 1,107 total
includes taxes & fees
13 Jul - 14 Jul
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Beautiful Cottage between Lake Moultrie and Lake Marion
Smart TV, video games, DVD player, books

Beautiful Cottage between Lake Moultrie and Lake Marion

9.8 out of 10, Exceptional, (136)
"Property as described! Great stay!"
Beautiful Cottage between Lake Moultrie and Lake Marion
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Aerial view

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (31)
"Definitely would stay again , "
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Property grounds

The Bunkhouse at St Julien - Vintage Waterfront Lake House

10.0 out of 10, Exceptional, (22)
"plenty of room, quiet, and perfect for a family getaway"
The Bunkhouse at St Julien - Vintage Waterfront Lake House
Stunning Lake Moultrie Estate on Deep Water
Exterior

Stunning Lake Moultrie Estate on Deep Water

10.0 out of 10, Exceptional, (15)
"Comfotable and very homey. Loved the fireplace. Would love to stay there in the summer."
Stunning Lake Moultrie Estate on Deep Water
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free