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Go beyond your typical stay in Mosopuquio

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Check prices for these dates

Tonight
11 Nov - 12 Nov
Tomorrow
12 Nov - 13 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Mosopuquio hotels

A lakeside building with a reflection in the water, surrounded by trees.

1. Hotel El Lago by Luoxo

Hotel El Lago by Luoxo
3.5 star property
SabandĆ­a
8.4 out of 10, Very good, (191 reviews)
"Beautiful property with a very helpful staff. The manager was very accomodating and friendly. Great food at the restaurant too."
United States
Cory
The price is SARĀ 234
SARĀ 257 total
12 Nov - 13 Nov
Hotel El Lago by Luoxo
An indoor dining area with wicker chairs and tables, wooden ceiling beams, and a view of the cityscape through large windows.

2. Sonesta Hotel Arequipa

Sonesta Hotel Arequipa
4.0 star property
Cerro Colorado District
9.6 out of 10, Exceptional, (226 reviews)
"Great location. Great breakfast bar and superb attention to detail. Customer service was good, very pleasant people. Will stay again upon my return to Arequipa."
United States
denisse
The price is SARĀ 395
SARĀ 435 total
21 Nov - 22 Nov
Sonesta Hotel Arequipa
A restaurant with a tiled backsplash, wooden chairs, and a counter with a mirror and plants.

3. Hostal Lirium

Hostal Lirium
3.0 star property
Sachaca
10.0 out of 10, Exceptional, (2 reviews)
"The room was pleasant and always clean for us after a long day. Breakfast was always on the table before we showed up to the table. Staff was very friendly and helpful. A 10 min walk away from the Plaza de Armas, quite place if you like to stay away from the noise. "
United States
Alexander
The price is SARĀ 91
SARĀ 91 total
22 Nov - 23 Nov
Hostal Lirium
Room

4. Hotel TerraMistica Monasterio

Hotel TerraMistica Monasterio
3.0 star property
JosƩ Luis Bustamante y Rivero
10.0 out of 10, Exceptional, (2 reviews)
"Very nice location and friendly staff ļ¼› room is not big, but adequate; will stay again if I am back to Arequipa"
United States
Sheauing
The price is SARĀ 170
SARĀ 170 total
12 Nov - 13 Nov
Hotel TerraMistica Monasterio
A hotel lobby with a reception desk, a seating area with patterned chairs, a glass coffee table, and a chandelier.

5. HOTEL ALTIVA

HOTEL ALTIVA
3.0 star property
Cayma
The price is SARĀ 112
SARĀ 112 total
13 Nov - 14 Nov
HOTEL ALTIVA
A hotel room with a bed, bedside table, lamp, and a small table with a vase of sunflowers.

6. Los Tambos - Boutique

Los Tambos - Boutique
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (559 reviews)
"Loved this hotel ! The staff is super accommodating and helpful, the breakfast was really good and the view from the terrace was wonderful!"
Canada
sabine
The price is SARĀ 204
SARĀ 224 total
2 Dec - 3 Dec
Los Tambos - Boutique
A bar area with wooden wall shelves holding bottles, a polished granite countertop, and modern bar stools.

7. Mint Hotel

Mint Hotel
4.0 star property
Historical Center
9.2 out of 10, Wonderful, (131 reviews)
"I travelled with family and we had a great experience at Mint Hotel! The property location is great, it took approximately 10-15 mins by car to the main attractions. The staff and restaurant service were amazing!"
Canada
Gayaththri
The price is SARĀ 253
SARĀ 273 total
14 Nov - 15 Nov
Mint Hotel
A bathtub with rose petals and champagne glasses.

8. Hotel La Cuesta de Cayma

Hotel La Cuesta de Cayma
3.0 star property
Cayma
8.6 out of 10, Excellent, (34 reviews)
"Good hotel. Staff were very helpful"
United Kingdom
Max
The price is SARĀ 247
SARĀ 261 total
1 Dec - 2 Dec
Hotel La Cuesta de Cayma
Hotel Santa Rosa with a classic facade, a prominent entrance, and a balcony with flowers.

9. Hotel Santa Rosa

Hotel Santa Rosa
3.0 star property
Historical Center
9.2 out of 10, Wonderful, (27 reviews)
"Love it! Cute hotel right in the middle of the historic center and one of the busiest streets, plenty of restaurants and bars to walk to right on the same street. Would definitely stay here again!"
United States
Christian
The price is SARĀ 184
SARĀ 184 total
12 Nov - 13 Nov
Hotel Santa Rosa
A picnic setup with food and drinks on a wooden table in a grassy area with a tree and a llama in the background.

10. Wyndham Costa del Sol Arequipa

Wyndham Costa del Sol Arequipa
5.0 star property
Historical Center
9.4 out of 10, Exceptional, (341 reviews)
"Very comfy hotel and Juanita the tortoise is a real highlight"
United Kingdom
Jordan
The price is SARĀ 539
SARĀ 593 total
22 Nov - 23 Nov
Wyndham Costa del Sol Arequipa
A stone arched window with a cushioned bench and two pillows, overlooking a garden with plants and a door.

11. Hampton by Hilton Arequipa

Hampton by Hilton Arequipa
4.0 star property
Historical Center
9.6 out of 10, Exceptional, (162 reviews)
"The property has a buffet breakfast that it was excellent ."
United States
Viviana
The price is SARĀ 368
SARĀ 405 total
4 Dec - 5 Dec
Hampton by Hilton Arequipa
A rooftop patio with round wooden tables and chairs, potted plants, and umbrellas.

12. Casa Andina Standard Arequipa

Casa Andina Standard Arequipa
3.5 star property
Historical Center
8.4 out of 10, Very good, (201 reviews)
"This was a great hotel. Near the plaza but without all crowds. Breakfast was ready each morning at 6sm with many options. The front desk staff was always helpful and courteous"
United States
Eileen
The price is SARĀ 290
SARĀ 319 total
13 Nov - 14 Nov
Casa Andina Standard Arequipa
An outdoor dining area with tables and chairs, lanterns, and a view of a historic building with two towers and a mountain in the background.

13. Katari Hotel At Plaza de Armas

Katari Hotel At Plaza de Armas
3.5 star property
Historical Center
9.4 out of 10, Exceptional, (328 reviews)
"The beds were very large and comfortable. Breakfast was excellent as well as the location."
United States
James
The price is SARĀ 361
SARĀ 397 total
23 Nov - 24 Nov
Katari Hotel At Plaza de Armas
A hotel lobby with a dining area, a piano, and a television.

14. Xima Arequipa Crismar

Xima Arequipa Crismar
3.0 star property
Historical Center
8.6 out of 10, Excellent, (23 reviews)
"Great wonderful clean hotel with attentive staff. Best stay in Arequipa so far. Spacious renovated rooms and delicious breakfast. This is the hotel I will always be staying when visiting the city."
United States
Lana
The price is SARĀ 188
SARĀ 207 total
10 Dec - 11 Dec
Xima Arequipa Crismar
A breakfast table with a variety of dishes, a vase with flowers, and a potted plant by a window with columns.

15. Casa Arequipa

Casa Arequipa
3.0 star property
Historical Center
9.4 out of 10, Exceptional, (80 reviews)
"Very helpful staff."
United States
John
The price is SARĀ 233
SARĀ 233 total
16 Nov - 17 Nov
Casa Arequipa
A multi-level atrium with a central reflective pool, balconies, and a mix of modern and traditional architectural elements.

16. Palla Boutique Hotel

Palla Boutique Hotel
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (132 reviews)
"Staff were very helpful and everything was perfect"
Canada
Raymond
The price is SARĀ 255
SARĀ 280 total
11 Dec - 12 Dec
Palla Boutique Hotel
A courtyard with wicker furniture, potted plants, and a tiled floor.

17. Los Tambos - Colonial

Los Tambos - Colonial
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (73 reviews)
"Great hotel in a very convenient location. The building itself is beautiful, the made-to-order breakfasts were excellent, and all the staff were very friendly and welcoming. We'd happily stay here again."
United Kingdom
martin
The price is SARĀ 167
SARĀ 183 total
12 Nov - 13 Nov
Los Tambos - Colonial
A breakfast table with various dishes, a coffee cup, and a juice glass.

18. Hotel Los Angeles

Hotel Los Angeles
3.0 star property
Historical Center
8.0 out of 10, Very good, (7 reviews)
"Decent hotel in a good location. The manager was lovely and the breakfast was good. Thank you for a lovely stay"
United States
Emily
The price is SARĀ 116
SARĀ 116 total
12 Nov - 13 Nov
Hotel Los Angeles
A well-maintained garden with various potted plants and flowers, a large decorative pot, and a stone pathway.

19. HOTEL AREQUIPA INN

HOTEL AREQUIPA INN
3.0 star property
Historical Center
9.6 out of 10, Exceptional, (103 reviews)
"Clean room , friendly staff"
United States
Maria
The price is SARĀ 161
SARĀ 161 total
12 Nov - 13 Nov
HOTEL AREQUIPA INN
A buffet with various food items, including bread, sandwiches, and a bowl of guacamole with tomatoes.

20. Hotel Villa del Carmen

Hotel Villa del Carmen
3.0 star property
Historical Center
8.6 out of 10, Excellent, (14 reviews)
"The rrom where ok. The finishes where not bad. TV is lousy. but the cafeteria must be better. The food was lousy striving for ok. and it was very depressing, the area where to eat. DidnĀ“t like that Ć”rt very much,"
United States
Gabriel
The price is SARĀ 188
SARĀ 188 total
12 Nov - 13 Nov
Hotel Villa del Carmen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mosopuquio Hotel Reviews

An indoor dining area with wicker chairs and tables, wooden ceiling beams, and a view of the cityscape through large windows.
Sonesta Hotel Arequipa

Sonesta Hotel Arequipa

Sonesta Hotel Arequipa
Cerro Colorado District

10/10 Excellent

Great location. Great breakfast bar and superb attention to detail. Customer service was good, very pleasant people. Will stay again upon my return to Arequipa.
United States
denisse
Reviewed November 5, 2026
Sonesta Hotel Arequipa

Frequently Asked Questions

What are some of the best vacation home rentals that Mosopuquio has to offer?

Fast Wifi, Jacuzzi, washer & dryer, bbq, 4br, High Security, stylishly designed: This vacation home rental near Mosopuquio offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation. See all vacation rentals in Mosopuquio.

If I need to cancel my hotel reservation in Mosopuquio, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mosopuquio.

Where can I learn more about changing or cancelling my trip to Mosopuquio?

To find more details about changing or cancelling your trip to Mosopuquio, go to https://www.expedia.com/service/.