Find hotels in Mesopotamia from SAR 159

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Compare 44 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Guest House Ilektra

9.8 out of 10, Exceptional, (6)
"We were doing a project in nearby Pentalofos so we had long work days. The area is quiet and it's a wonderful departure from the business of the city. The rooms were quite comfortable and my room had everything I needed. I had a small fridge and a stove to cook up anything if I wanted. Part way through my trip I was able to coordinate laundry services. My room had a wonderful view of the sunrise, which was a great sight to wake up to. The rooms are always clean and warm, it felt like a home...
The price is SAR 192
SAR 227 total
includes taxes & fees
21 Jul - 22 Jul
Guest House Ilektra

Hotel Anastassiou

2.0 star property
8.0 out of 10, Very Good, (64)
"Nice hotel. Nice room. Nice people!! Not walkable to town but a very short drive! And a very lovable property pup!! Thank you for your hospitality!! "
The price is SAR 159
SAR 189 total
includes taxes & fees
27 Jul - 28 Jul
Hotel Anastassiou

Guesthouse Vissinokipos

9.4 out of 10, Exceptional, (10)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
Guesthouse Vissinokipos

To Spiti tis Sofias

The price is SAR 249
SAR 291 total
includes taxes & fees
4 Aug - 5 Aug
To Spiti tis Sofias

Limneon Resort & Spa

4.0 star property
9.2 out of 10, Wonderful, (181)
"The hotel is beautiful. Service and cleaniness foe this property is the BEST!!!!Friendly staff. "
The price is SAR 347
SAR 437 total
includes taxes & fees
27 Jul - 28 Jul
Limneon Resort & Spa

Calma Hotel & Spa

4.0 star property
9.6 out of 10, Exceptional, (34)
"Great place to relax. Very kind staff all over. Nice breakfast buffet."
Calma Hotel & Spa

Arhontiko Christodoulou

2.0 star property
Arhontiko Christodoulou

Esperos Palace Luxury & Spa Hotel

4.0 star property
9.0 out of 10, Wonderful, (83)
The price is SAR 361
SAR 454 total
includes taxes & fees
22 Jul - 23 Jul
Esperos Palace Luxury & Spa Hotel

Chloe Hotel

3.0 star property
10.0 out of 10, Exceptional, (83)
"We enjoyed the stay, friendly staff and nice breakfast "
The price is SAR 353
SAR 423 total
includes taxes & fees
23 Jul - 24 Jul
Chloe Hotel

Orologopoulos Mansion

5.0 star property
9.6 out of 10, Exceptional, (33)
"Wonderful Boutique hotel in center of old town"
Orologopoulos Mansion

Kyknos De Luxe Hotel

10.0 out of 10, Exceptional, (42)
"Very nice clean, very polite staff and great breakfast!"
The price is SAR 297
SAR 359 total
includes taxes & fees
21 Jul - 22 Jul
Kyknos De Luxe Hotel

Anesis Hotel

2.0 star property
9.0 out of 10, Wonderful, (9)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
The price is SAR 211
SAR 249 total
includes taxes & fees
21 Jul - 22 Jul
Anesis Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Mesopotamia

Head to Kastoria Lake and Dragon's Lair—just two of the sights around Mesopotamia.

Top Mesopotamia Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Mesopotamia?

To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Chloe Hotel. See all available top hotels, or vacation rentals in Mesopotamia.

What are some of the best vacation home rentals that Mesopotamia has to offer?

The Little Stone House by the Lake / Το Πέτρινο Σπιτάκι δίπλα στη Λίμνη: This vacation home rental outside of Mesopotamia is located on a lake and has a fireplace, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, an oven, and a microwave. See all vacation rentals in Mesopotamia.

If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?

Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.

Where can I learn more about changing or cancelling my trip to Mesopotamia?

For more details about picking new dates or cancelling your trip to Mesopotamia, click here.

What is the best accommodation for staying close to Macedonia Airport (SKG)?

Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.

What is staying in Mesopotamia like?

Travelers to Mesopotamia will find plenty to explore and enjoy. There are 44 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.

What are the top places to visit in Mesopotamia?

Places to visit in the wider area include Kastoria Lake, Dragon's Lair, and Holy Monastery of Panagias Mauriotissas. You'll also find Kastoria Aquarium and Folklore Museum of Kastoria in the area. Check out what more to see and do in Expedia's Mesopotamia guide.

What's the seasonal weather like in Mesopotamia?

The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.