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Check prices for these dates

Tonight
6 Feb - 7 Feb
Tomorrow
7 Feb - 8 Feb
This weekend
6 Feb - 8 Feb
Next weekend
13 Feb - 15 Feb

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Our top choices for Louisville Science Center hotels

Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Location and the staff was fabulous."
United States
Madeline
The price is SAR 671
SAR 809 total
includes taxes & fees
18 Feb - 19 Feb
21c Museum Hotel Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (444 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
The price is SAR 762
SAR 896 total
includes taxes & fees
8 Mar - 9 Mar
Hotel Distil, Autograph Collection
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,005 reviews)
"Property was very well taken care of and unique. Staff was friendly and helpful. Room was very nice and the price was great!"
United States
Erica
The price is SAR 695
SAR 818 total
includes taxes & fees
22 Feb - 23 Feb
The Grady
Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Super nice staff, everything was perfect!"
United States
Robyn
The price is SAR 447
SAR 526 total
includes taxes & fees
16 Feb - 17 Feb
Homewood Suites by Hilton Louisville Downtown, KY
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,180 reviews)
"Very beautiful facility and great location "
United States
Anthony
The Brown Hotel
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (100 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is SAR 493
SAR 572 total
includes taxes & fees
9 Feb - 10 Feb
DuPont Mansion Bed & Breakfast
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is SAR 695
SAR 785 total
includes taxes & fees
19 Feb - 20 Feb
Market Street Inn
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay "
United States
Sarah
The price is SAR 404
SAR 476 total
includes taxes & fees
28 Feb - 1 Mar
Cambria Hotel Louisville Downtown-Whiskey Row
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,777 reviews)
"Amazing stay! "
United States
Erin
The price is SAR 777
SAR 914 total
includes taxes & fees
8 Feb - 9 Feb
Omni Louisville Hotel
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is SAR 416
SAR 679 total
includes taxes & fees
22 Feb - 23 Feb
Stellar Suites
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (907 reviews)
"Always a great place to stay."
United States
Christopher
The price is SAR 412
SAR 485 total
includes taxes & fees
1 Mar - 2 Mar
Tempo By Hilton Louisville Downtown Nulu
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (714 reviews)
"First time trying a moxy, will be staying with moxy hotels from now on"
United States
Robinson
The price is SAR 420
SAR 494 total
includes taxes & fees
27 Feb - 28 Feb
Moxy Louisville Downtown
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (536 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is SAR 428
SAR 503 total
includes taxes & fees
19 Feb - 20 Feb
Towneplace Suites By Marriott Louisville Downtown
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (70 reviews)
"i love this place"
United States
THANH
The price is SAR 643
SAR 756 total
includes taxes & fees
22 Feb - 23 Feb
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,694 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is SAR 308
SAR 362 total
includes taxes & fees
17 Feb - 18 Feb
Holiday Inn Express & Suites Louisville Downtown by IHG
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,150 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is SAR 430
SAR 506 total
includes taxes & fees
15 Feb - 16 Feb
Embassy Suites Louisville Downtown
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Great staff, good bar. "
United States
Edward
The price is SAR 391
SAR 460 total
includes taxes & fees
8 Mar - 9 Mar
Aloft Louisville Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,034 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is SAR 469
SAR 552 total
includes taxes & fees
8 Feb - 9 Feb
Hotel Genevieve part of JdV by Hyatt
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (621 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is SAR 443
SAR 521 total
includes taxes & fees
15 Feb - 16 Feb
AC Hotel Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is SAR 739
SAR 869 total
includes taxes & fees
28 Feb - 1 Mar
Louisville Marriott Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,003 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
444 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,005 reviews
View
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,003 reviews
View
Interior
The Brown Hotel
4.5 star property
9.4
Exceptional
1,180 reviews
View

Top Louisville Science Center Hotel Reviews

Omni Louisville Hotel

Omni Louisville Hotel

10/10 Excellent
"Excellent location, unique common areas, good food and plenty to experience without leaving the hotel. Library bar, speak easy, two restaurants and attached marketplace offers a wide variety. Staff are friendly. Rooms clean and spacious. Highly recommend. "
dana 1-night trip
Posted 7 days ago
Omni Louisville Hotel

Hotels near other Louisville Science Center attractions

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

4.5/5 (1,200 reviews)
You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
See properties
Muhammad Ali Center featuring modern architecture and night scenes

Muhammad Ali Center

4.3/5 (298 reviews)
You can spend an afternoon studying the exhibits at Muhammad Ali Center during your trip to Louisville. Stroll along the area's riverfront or experience its fascinating museums.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 308 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, 21c Museum Hotel Louisville is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a restaurant. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 308 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.