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Our top choices for Louisville Science Center hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Location and the staff was fabulous."
United States
Madeline
The price is SAR 671
SAR 809 total
includes taxes & fees
17 Feb - 18 Feb
21c Museum Hotel Louisville

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,005 reviews)
"Property was very well taken care of and unique. Staff was friendly and helpful. Room was very nice and the price was great!"
United States
Erica
The price is SAR 695
SAR 818 total
includes taxes & fees
22 Feb - 23 Feb
The Grady

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (22 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is SAR 994
SAR 1,154 total
includes taxes & fees
10 Feb - 11 Feb
Louisville Bourbon Inn

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (100 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is SAR 493
SAR 572 total
includes taxes & fees
10 Feb - 11 Feb
DuPont Mansion Bed & Breakfast

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is SAR 695
SAR 785 total
includes taxes & fees
10 Feb - 11 Feb
Market Street Inn

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (444 reviews)
"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "
United States
Carol
The price is SAR 826
SAR 972 total
includes taxes & fees
15 Feb - 16 Feb
Hotel Distil, Autograph Collection

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,181 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is SAR 434
SAR 699 total
includes taxes & fees
1 Mar - 2 Mar
Stellar Suites

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay "
United States
Sarah
The price is SAR 404
SAR 476 total
includes taxes & fees
28 Feb - 1 Mar
Cambria Hotel Louisville Downtown-Whiskey Row

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (538 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is SAR 428
SAR 503 total
includes taxes & fees
1 Mar - 2 Mar
Towneplace Suites By Marriott Louisville Downtown

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,057 reviews)
"Great hotel"
United States
Lazaro
The price is SAR 585
SAR 689 total
includes taxes & fees
18 Feb - 19 Feb
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,779 reviews)
"Amazing stay! "
United States
Erin
The price is SAR 777
SAR 914 total
includes taxes & fees
10 Feb - 11 Feb
Omni Louisville Hotel

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (71 reviews)
"i love this place"
United States
THANH
The price is SAR 643
SAR 756 total
includes taxes & fees
22 Feb - 23 Feb
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (715 reviews)
"First time trying a moxy, will be staying with moxy hotels from now on"
United States
Robinson
The price is SAR 420
SAR 494 total
includes taxes & fees
27 Feb - 28 Feb
Moxy Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,155 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is SAR 430
SAR 506 total
includes taxes & fees
15 Feb - 16 Feb
Embassy Suites Louisville Downtown

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,036 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is SAR 506
SAR 596 total
includes taxes & fees
15 Feb - 16 Feb
Hotel Genevieve part of JdV by Hyatt

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,697 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is SAR 308
SAR 362 total
includes taxes & fees
15 Feb - 16 Feb
Holiday Inn Express & Suites Louisville Downtown by IHG

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is SAR 739
SAR 869 total
includes taxes & fees
28 Feb - 1 Mar
Louisville Marriott Downtown

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (621 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is SAR 472
SAR 556 total
includes taxes & fees
15 Feb - 16 Feb
AC Hotel Louisville Downtown

TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (657 reviews)
"Best hotel and staff ever "
United States
Cheryl
The price is SAR 420
SAR 475 total
includes taxes & fees
26 Feb - 27 Feb
TownePlace Suites by Marriott Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,003 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,005 reviews
View
Interior entrance
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
22 reviews
View
Front of property
DuPont Mansion Bed & Breakfast
3.0 star property
9.8
Exceptional
100 reviews
View
Interior entrance
Market Street Inn
3.5 star property
9.8
Exceptional
120 reviews
View

Top Louisville Science Center Hotel Reviews

Hotels near other Louisville Science Center attractions

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 308 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, 21c Museum Hotel Louisville is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a restaurant. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 308 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.

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