The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

SAR 382

SAR 433 total

includes taxes & fees

18 Oct - 19 Oct

Iron/ironing board, cribs (free), rollaway beds (surcharge), bed sheets

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Heather

SAR 549

SAR 623 total

includes taxes & fees

1 Oct - 2 Oct

Standard Room, 2 Queen Beds | Pillowtop beds, in-room safe, desk, laptop workspace

Pillowtop beds, in-room safe, desk, laptop workspace

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Gwen

SAR 473

SAR 537 total

includes taxes & fees

25 Oct - 26 Oct

Studio Suite, 2 Double Beds, Kitchen | In-room safe, desk, iron/ironing board, WiFi (free)

In-room safe, desk, iron/ironing board, WiFi (free)

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

SAR 458

SAR 520 total

includes taxes & fees

18 Oct - 19 Oct

5. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

daryl

SAR 439

SAR 503 total

includes taxes & fees

17 Oct - 18 Oct

Coffee/tea maker, fridge, microwave, stovetop

Suite, Multiple Beds, Non Smoking | Premium bedding, blackout drapes, iron/ironing board, WiFi (free)

6. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

SAR 348

SAR 395 total

includes taxes & fees

23 Oct - 24 Oct

Coffee/tea maker, full-size fridge, microwave, stovetop

7. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Darren

SAR 460

SAR 522 total

includes taxes & fees

11 Oct - 12 Oct

8. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Rebecca

SAR 522

SAR 592 total

includes taxes & fees

18 Oct - 19 Oct

Room, 2 Queen Beds, Non Smoking | Premium bedding, down comforters, pillowtop beds, in-room safe

Premium bedding, down comforters, pillowtop beds, in-room safe

9. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Teresa

SAR 336

SAR 389 total

includes taxes & fees

27 Sep - 28 Sep

10. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

SAR 372

SAR 422 total

includes taxes & fees

18 Oct - 19 Oct

Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

William

SAR 328

SAR 372 total

includes taxes & fees

18 Oct - 19 Oct

Standard Room, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

12. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

SAR 308

SAR 349 total

includes taxes & fees

25 Oct - 26 Oct

Studio, 1 King Bed, Non Smoking | Desk, WiFi (free), bed sheets

Studio, 1 Queen Bed, Accessible, Non Smoking | Desk, WiFi (free), bed sheets

13. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

SAR 314

SAR 357 total

includes taxes & fees

11 Oct - 12 Oct

Standard Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, laptop workspace, blackout drapes

14. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Stephen

SAR 323

SAR 366 total

includes taxes & fees

4 Oct - 5 Oct

Studio Suite, Multiple Beds, Microwave (Wet Bar) | Private kitchen | Fridge

Indoor pool, open 8:00 AM to 10:00 PM, sun loungers

15. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

SAR 462

SAR 524 total

includes taxes & fees

4 Oct - 5 Oct

16. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Deanna

SAR 424

SAR 486 total

includes taxes & fees

25 Oct - 26 Oct

Desk, laptop workspace, blackout drapes, iron/ironing board

17. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

SAR 428

SAR 503 total

includes taxes & fees

11 Oct - 12 Oct

Premium bedding, in-room safe, desk, laptop workspace

18. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

SAR 394

SAR 448 total

includes taxes & fees

27 Sep - 28 Sep

Standard Room, 1 Queen Bed, Jetted Tub | Iron/ironing board, WiFi (free), individually decorated

19. Walnut Street Inn

6.7 km from Lester E. Cox Medical Center South

Alan

SAR 520

SAR 591 total

includes taxes & fees

27 Sep - 28 Sep

20. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Ashley

SAR 410

SAR 475 total

includes taxes & fees

27 Sep - 28 Sep

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 712 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 557 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,000 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 433 reviews	View
Hilton Garden Inn Springfield, MO	9.0 Wonderful 875 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"The house was clean. Good location, close to everything. Nice fenced in yard. Quite neighborhood."

The Bradford Hotel, an Ascend Collection Hotel

8/10 Good

"staff stuffy and jacket required to eat"

Homewood Suites by Hilton Springfield Medical District

10/10 Excellent

"The bed was not comfortable pillows was worn to flat; shower door would not stay closed water got on the floor each time I showered...the kitchen area was fine didn't use it. The staff and room attendants were awesome very friendly. The breakfast area felt really comfortable to sit to eat and enjoy your family."

MainStay Suites Springfield South - Battlefield Rd

10/10 Excellent

"Enjoy staying there !"

Residence Inn by Marriott Springfield

10/10 Excellent

"Beautiful hotel, Excellent breakfast. Staff is friendly. Conveniently located"

Comfort Inn South - Springfield

10/10 Excellent

"Enjoyed our clean and comfortable room and bed. Staff was very friendly (front desk and cleaning staff). Enjoyed the nice choices for breakfast and breakfast area. Nice having coffe and tea in the room."

Element by Marriott Springfield South

10/10 Excellent

"Super clean, great amenities, planning to stay here anytime we visit Springfield."

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Good location and beautiful home."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Spacious house and very well maintained. Host was very responsive on answering our questions. We do an annual family reunion and this worked very well for us. Would definitely stay here again while in the area."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 19 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Find hotels near Lester E. Cox Medical Center South, Springfield from SAR 349

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Hilton Garden Inn Springfield, MO

6. MainStay Suites Springfield South - Battlefield Rd

7. Residence Inn by Marriott Springfield

8. Element by Marriott Springfield South

9. La Quinta Inn & Suites by Wyndham Springfield South

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Hampton Inn Springfield-Southeast

16. Drury Inn & Suites Springfield, MO

17. SpringHill Suites by Marriott Springfield North

18. Holiday Inn Express & Suites Springfield North by IHG

19. Walnut Street Inn

20. Fairfield Inn & Suites by Marriott Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Peaceful Retreat near Medical Mile in Springfield

The Bradford Hotel, an Ascend Collection Hotel

Homewood Suites by Hilton Springfield Medical District

MainStay Suites Springfield South - Battlefield Rd

Residence Inn by Marriott Springfield

Comfort Inn South - Springfield

Element by Marriott Springfield South

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Frequently asked questions