The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

A gym with various exercise machines, a clock, and a motivational sign.

A living room with patterned armchairs, a dark sofa, a glass coffee table, and framed artwork on the walls.

A business center with two computers, a printer, and a lamp. There are signs indicating the business center is available 24 hours and providing emergency and front desk contact information.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

SAR 382

SAR 433 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel with a dark facade, multiple windows, and an American flag.

A modern hotel room with a large bed, a desk with a chair, a mirror, and a painting on the wall.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Aaron

SAR 528

SAR 599 total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with a blue sofa, two single beds, a nightstand, a lamp, and a framed picture on the wall.

A living room with a blue sofa, a small round table, a patterned carpet, and a kitchenette area.

A Holiday Inn Express & Suites hotel with a parking lot, a covered entrance, and a view of the surrounding area.

A coffee station with two coffee machines and a variety of coffee pods and cups.

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Gwen

SAR 473

SAR 537 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

A multi-story hotel with a prominent "Candlewood Suites" sign, a parking lot, and a landscaped entrance area.

A spacious lobby with a pool, comfortable seating, and a reception desk.

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

SAR 469

SAR 533 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with large windows, a bar, and modern furniture.

A modern kitchen with a bar area, featuring a large TV, wooden shelves, and bar stools.

A spacious kitchen with a large island, ample seating, and a view of the cityscape through large windows.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

5. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Rebecca

SAR 541

SAR 614 total

includes taxes & fees

18 Oct - 19 Oct

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A compact kitchen with a microwave, toaster, and refrigerator.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

6. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

SAR 335

SAR 380 total

includes taxes & fees

13 Oct - 14 Oct

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

A lobby with a fireplace, large windows, and a view of the outdoors.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

A hotel with a stone facade, large windows, and a clear blue sky.

7. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

daryl

SAR 428

SAR 490 total

includes taxes & fees

31 Oct - 1 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

A buffet setup with various food items, a clock, and a coffee machine.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

A modern kitchen with a central island, bar stools, a dining table, and a bar area.

8. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Jacob

SAR 444

SAR 504 total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

9. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Denise

SAR 333

SAR 385 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A hotel with a prominent sign, a covered parking area, and a well-lit entrance.

A swimming pool with a lifeguard tower, surrounded by a fence and seating area.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

10. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

William

SAR 338

SAR 383 total

includes taxes & fees

29 Oct - 30 Oct

A hotel lobby with a reception desk, a staircase, and a seating area.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

11. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

SAR 330

SAR 375 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

A hotel room with a brown leather sofa, a small table, a floor lamp, and a green accent wall.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

12. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

SAR 280

SAR 318 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A gym with exercise equipment, a treadmill, and a wall mural of athletes.

A modern dining area with blue chairs and white tables, a flat-screen TV mounted on the wall, and a wooden cabinet with items on it.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

13. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Stephen

SAR 310

SAR 352 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A conference room with rows of tables and chairs, a flat-screen TV on the wall, and a door in the background.

A gym with treadmills, weight machines, and exercise mats.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

14. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

SAR 402

SAR 456 total

includes taxes & fees

1 Nov - 2 Nov

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

A hotel room with a bed, bedside lamps, a desk with a sink, and a framed picture on the wall.

An indoor swimming pool with a clear water line, surrounded by lounge chairs and tables.

15. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

SAR 416

SAR 472 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

A hotel reception area with a modern design, including a reception desk, a wall with geometric patterns, and a minibar.

16. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

SAR 428

SAR 503 total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A modern kitchen with a long counter, wooden cabinets, and a backsplash.

A Drury Inn & Suites hotel with a modern design, featuring a prominent entrance and stone pillars.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

17. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Deanna

SAR 417

SAR 477 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern living room with a wooden dining table, comfortable seating, a stone accent wall, and a large window.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

An indoor swimming pool with clear glass walls, lounge chairs, and a lifeguard chair.

18. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Ashley

SAR 443

SAR 513 total

includes taxes & fees

18 Oct - 19 Oct

A room with a bed, a desk, a chair, a round table, and a ceiling fan.

A dining room with a wooden table set for six, surrounded by wooden chairs. There are framed pictures on the wall, a potted plant, and a red floor lamp.

19. Walnut Street Inn

6.7 km from Lester E. Cox Medical Center South

Alan

SAR 520

SAR 591 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio area with a stone wall, a fire pit, and outdoor seating.

A modern restaurant with a long counter, multiple seating areas, and a variety of tableware displayed on shelves.

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a parking area with a handicap parking space.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the parking lot outside.

20. Home2 Suites by Hilton Springfield North

Parkwood, 11.4 km from Lester E. Cox Medical Center South

Vicky

SAR 536

SAR 613 total

includes taxes & fees

25 Oct - 26 Oct

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 715 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 561 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,001 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 434 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 152 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Homewood Suites by Hilton Springfield Medical District

10/10 Excellent

"This is the cleanest nicest hotel I’ve ever stayed in staff was wonderful. The room was perfect and the entire property itself was very well maintained . I will definitely be staying here again for all future stays."

Residence Inn by Marriott Springfield

10/10 Excellent

"Best hotel we’ve stayed at, & we’ve stayed at A Lot for work!! Staff is awesome & ever nice!! We will absolutely be staying here from now on!!"

Candlewood Suites Springfield-Medical District

10/10 Excellent

"There was some issues with smells from other unit, people use these for extended stays and must cook alot in them, so we woke up to burning smells throughout the night and early morning."

Hampton Inn Springfield-South

8/10 Good

"Good variety for breakfast."

MainStay Suites Springfield South - Battlefield Rd

8/10 Good

"A very spacious room and nice sized kitchen with full size appliances"

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"The house was better than described, very comfortable and everything is right there I mean right there, I was pleasantly surprised on how I was able to get ot everything in no time flat, the only thing that was a hike was the airport."

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"The staff was so friendly and the breakfast was great. Very convenient location for travelers - places to eat and gas up so nearby."

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Property was clean and properly prepared for our stay. The deck was a wonderful addition for our gatherings."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"The house was clean. Good location, close to everything. Nice fenced in yard. Quite neighborhood."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 19 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Find hotels near Lester E. Cox Medical Center South, Springfield from SAR 318

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Treat yourself

Be picky

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Element by Marriott Springfield South

6. MainStay Suites Springfield South - Battlefield Rd

7. Hilton Garden Inn Springfield, MO

8. Residence Inn by Marriott Springfield

9. La Quinta Inn & Suites by Wyndham Springfield South

10. The Bradford Hotel, an Ascend Collection Hotel

11. Sleep Inn Springfield South I60 near Medical District

12. Extended Stay America Select Suites Springfield South

13. Clarion Pointe Springfield Southeast

14. Holiday Inn Express & Suites Springfield North by IHG

15. Hampton Inn Springfield-Southeast

16. SpringHill Suites by Marriott Springfield North

17. Drury Inn & Suites Springfield, MO

18. Fairfield Inn & Suites by Marriott Springfield North

19. Walnut Street Inn

20. Home2 Suites by Hilton Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Homewood Suites by Hilton Springfield Medical District

Residence Inn by Marriott Springfield

Candlewood Suites Springfield-Medical District

Hampton Inn Springfield-South

MainStay Suites Springfield South - Battlefield Rd

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Sleep Inn Springfield South I60 near Medical District

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Peaceful Retreat near Medical Mile in Springfield

Frequently asked questions