The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Bradford

SAR 382

SAR 433 total

includes taxes & fees

6 Sep - 7 Sep

Iron/ironing board, cribs (free), rollaway beds (surcharge), bed sheets

2. Homewood Suites by Hilton Springfield Medical District

1.4 km from Lester E. Cox Medical Center South

Heather

SAR 428

SAR 486 total

includes taxes & fees

6 Sep - 7 Sep

Standard Room, 2 Queen Beds | Pillowtop beds, in-room safe, desk, laptop workspace

Indoor pool, open 6 AM to 10 PM, sun loungers

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Dave

SAR 473

SAR 537 total

includes taxes & fees

6 Sep - 7 Sep

In-room safe, desk, iron/ironing board, WiFi (free)

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

SAR 428

SAR 486 total

includes taxes & fees

30 Aug - 31 Aug

5. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

Abel

SAR 413

SAR 473 total

includes taxes & fees

6 Sep - 7 Sep

Suite, 2 Bedrooms | Premium bedding, desk, iron/ironing board, cribs (free)

6. Residence Inn by Marriott Springfield

0.8 km from Lester E. Cox Medical Center South

Darren

SAR 412

SAR 467 total

includes taxes & fees

6 Sep - 7 Sep

Room, 2 Queen Beds, Non Smoking | Premium bedding, down comforters, pillowtop beds, in-room safe

Premium bedding, down comforters, pillowtop beds, in-room safe

Indoor pool, open 9:00 AM to 10:00 PM, sun loungers

7. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

KEVIN

SAR 345

SAR 399 total

includes taxes & fees

6 Sep - 7 Sep

Suite, Multiple Beds, Non Smoking | Premium bedding, blackout drapes, iron/ironing board, WiFi (free)

8. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Carla

SAR 348

SAR 395 total

includes taxes & fees

24 Sep - 25 Sep

Premium bedding, desk, blackout drapes, iron/ironing board

9. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

SAR 372

SAR 422 total

includes taxes & fees

20 Sep - 21 Sep

Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

10. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

Marlin Van

SAR 330

SAR 374 total

includes taxes & fees

20 Sep - 21 Sep

Standard Room, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

11. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Ping

SAR 312

SAR 355 total

includes taxes & fees

20 Sep - 21 Sep

Studio, 1 King Bed, Non Smoking | Desk, WiFi (free), bed sheets

Studio, 1 Queen Bed, Accessible, Non Smoking | Desk, WiFi (free), bed sheets

12. Extended Stay America Select Suites Springfield South

0.9 km from Lester E. Cox Medical Center South

Kayla

SAR 267

SAR 303 total

includes taxes & fees

27 Aug - 28 Aug

Standard Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, laptop workspace, blackout drapes

13. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

joseph

SAR 335

SAR 380 total

includes taxes & fees

20 Sep - 21 Sep

Studio, 2 Queen Beds, Refrigerator & Microwave (Wet Bar) | Private kitchen | Fridge

14. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Kenneth

SAR 431

SAR 489 total

includes taxes & fees

1 Sep - 2 Sep

Desk, laptop workspace, blackout drapes, iron/ironing board

15. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Katie

SAR 396

SAR 466 total

includes taxes & fees

20 Sep - 21 Sep

16. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Cindy

SAR 394

SAR 447 total

includes taxes & fees

30 Aug - 31 Aug

Standard Room, 1 Queen Bed, Jetted Tub | Iron/ironing board, WiFi (free), individually decorated

17. Walnut Street Inn

6.7 km from Lester E. Cox Medical Center South

Alan

SAR 520

SAR 591 total

includes taxes & fees

30 Aug - 31 Aug

Studio, 2 Queen Beds, Non Smoking (Xwide) | Premium bedding, in-room safe, desk, blackout drapes

18. Home2 Suites by Hilton Springfield North

Parkwood, 11.4 km from Lester E. Cox Medical Center South

Vicky

SAR 490

SAR 561 total

includes taxes & fees

6 Sep - 7 Sep

19. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Gregory

SAR 398

SAR 456 total

includes taxes & fees

30 Aug - 31 Aug

20. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Mariya

SAR 410

SAR 475 total

includes taxes & fees

20 Sep - 21 Sep

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 700 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 542 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,000 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 433 reviews	View
Hilton Garden Inn Springfield, MO	9.0 Wonderful 869 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

10/10 Excellent

"Greatest"

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"It was great, super clean, the staff was super friendly!!! The rooms were perfect, a little small but not bad at all!!! The only thing is I wouldn't count on the breakfast not a lot available, not the worst there is!!!! But could use a little more!"

Residence Inn by Marriott Springfield

10/10 Excellent

"Very nice place"

Homewood Suites by Hilton Springfield Medical District

10/10 Excellent

"Very clean hotel. Had everything we needed for our stay"

The Bradford Hotel, an Ascend Collection Hotel

8/10 Good

"Very nice hotel! Staff was very friendly and helpful. The pool was very clean and well taken care of. We had an issue with the tub and toilet, which was fixed very promptly. Highly recommend staying here, and would definitely stay here again."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"Nice cozy house. With full kitchen although we didn’t use it. Love pet friendly. Fenced in yard. No TV in bedrooms. But the one in the living room was good"

Hampton Inn Springfield-South

8/10 Good

"Everything was great, bed was a little too firm, but at least not broken down like some."

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"Wish the pool was bigger but it was good. Just gets crowded in the evenings."

3-bedroom house in serene Springfield. Medical Mile

10/10 Excellent

"The house was in a great location, close to the MO State University and hospitals. The house was very clean. Would definitely stay here again."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 21 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Find hotels near Lester E. Cox Medical Center South, Springfield from SAR 303

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Hilton Garden Inn Springfield, MO

6. Residence Inn by Marriott Springfield

7. La Quinta Inn & Suites by Wyndham Springfield South

8. MainStay Suites Springfield South - Battlefield Rd

9. Comfort Inn South - Springfield

10. The Bradford Hotel, an Ascend Collection Hotel

11. Sleep Inn Springfield South I60 near Medical District

12. Extended Stay America Select Suites Springfield South

13. Clarion Pointe Springfield Southeast

14. Hampton Inn Springfield-Southeast

15. SpringHill Suites by Marriott Springfield North

16. Holiday Inn Express & Suites Springfield North by IHG

17. Walnut Street Inn

18. Home2 Suites by Hilton Springfield North

19. Drury Inn & Suites Springfield, MO

20. Fairfield Inn & Suites by Marriott Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

Sleep Inn Springfield South I60 near Medical District

Residence Inn by Marriott Springfield

Homewood Suites by Hilton Springfield Medical District

The Bradford Hotel, an Ascend Collection Hotel

Peaceful Retreat near Medical Mile in Springfield

Hampton Inn Springfield-South

Holiday Inn Express and Suites Springfield Medical District by IHG

3-bedroom house in serene Springfield. Medical Mile

Frequently asked questions