The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

SAR 382

SAR 433 total

includes taxes & fees

27 Sep - 28 Sep

Iron/ironing board, cribs (free), rollaway beds (surcharge), bed sheets

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Heather

SAR 490

SAR 556 total

includes taxes & fees

26 Sep - 27 Sep

Standard Room, 2 Queen Beds | Pillowtop beds, in-room safe, desk, laptop workspace

Pillowtop beds, in-room safe, desk, laptop workspace

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Gwen

SAR 507

SAR 576 total

includes taxes & fees

4 Oct - 5 Oct

4. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Rebecca

SAR 560

SAR 635 total

includes taxes & fees

20 Sep - 21 Sep

Studio Suite, 2 Double Beds, Kitchen | In-room safe, desk, iron/ironing board, WiFi (free)

In-room safe, desk, iron/ironing board, WiFi (free)

5. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

SAR 488

SAR 554 total

includes taxes & fees

20 Sep - 21 Sep

6. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

Donald

SAR 428

SAR 490 total

includes taxes & fees

26 Sep - 27 Sep

Coffee/tea maker, full-size fridge, microwave, stovetop

Suite, 2 Bedrooms | Premium bedding, desk, iron/ironing board, cribs (free)

7. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Darren

SAR 460

SAR 522 total

includes taxes & fees

4 Oct - 5 Oct

Room, 2 Queen Beds, Non Smoking | Premium bedding, down comforters, pillowtop beds, in-room safe

Premium bedding, down comforters, pillowtop beds, in-room safe

Indoor pool, open 9:00 AM to 10:00 PM, sun loungers

8. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Teresa

SAR 340

SAR 392 total

includes taxes & fees

20 Sep - 21 Sep

Coffee/tea maker, fridge, microwave, stovetop

Suite, Multiple Beds, Non Smoking | Premium bedding, blackout drapes, iron/ironing board, WiFi (free)

9. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Katie

SAR 348

SAR 395 total

includes taxes & fees

13 Oct - 14 Oct

10. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

SAR 372

SAR 422 total

includes taxes & fees

4 Oct - 5 Oct

Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

Scott

SAR 332

SAR 377 total

includes taxes & fees

4 Oct - 5 Oct

Standard Room, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, WiFi (free)

12. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Ping

SAR 314

SAR 356 total

includes taxes & fees

4 Oct - 5 Oct

Studio, 1 King Bed, Non Smoking | Desk, WiFi (free), bed sheets

Studio, 1 Queen Bed, Accessible, Non Smoking | Desk, WiFi (free), bed sheets

13. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

SAR 308

SAR 349 total

includes taxes & fees

4 Oct - 5 Oct

Standard Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, laptop workspace, blackout drapes

14. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Stephen

SAR 305

SAR 346 total

includes taxes & fees

4 Oct - 5 Oct

Studio, 2 Queen Beds, Refrigerator & Microwave (Wet Bar) | Private kitchen | Fridge

Indoor pool, open 8:00 AM to 10:00 PM, sun loungers

15. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

SAR 416

SAR 472 total

includes taxes & fees

20 Sep - 21 Sep

Desk, laptop workspace, blackout drapes, iron/ironing board

16. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Katie

SAR 447

SAR 525 total

includes taxes & fees

27 Sep - 28 Sep

Premium bedding, in-room safe, desk, laptop workspace

17. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

SAR 394

SAR 448 total

includes taxes & fees

27 Sep - 28 Sep

Standard Room, 1 Queen Bed, Jetted Tub | Iron/ironing board, WiFi (free), individually decorated

18. Walnut Street Inn

6.7 km from Lester E. Cox Medical Center South

Alan

SAR 521

SAR 591 total

includes taxes & fees

16 Sep - 17 Sep

19. Home2 Suites by Hilton Springfield North

Parkwood, 11.4 km from Lester E. Cox Medical Center South

Vicky

SAR 505

SAR 578 total

includes taxes & fees

27 Sep - 28 Sep

20. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Gregory

SAR 398

SAR 456 total

includes taxes & fees

27 Sep - 28 Sep

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 708 708 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 552 552 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 1001 1,001 reviews	View
Element by Marriott Springfield South	9.2 146 146 reviews	View
Candlewood Suites Springfield-Medical District	9.2 433 433 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Element by Marriott Springfield South

10/10 Excellent

"Wonderful hotel and staff"

Sleep Inn Springfield South I60 near Medical District

10/10 Excellent

"Best hotel in the area"

The Bradford Hotel, an Ascend Collection Hotel

10/10 Excellent

"Clean rooms and helpful staff"

Hampton Inn Springfield-South

10/10 Excellent

"Good location, breakfast was great . If you stay in hotels often you know the gravy at hotel breakfast is not good. But this hotel has figured out how to make gravy! It also was reasonably priced . Located near shopping & restaurants"

Residence Inn by Marriott Springfield

10/10 Excellent

"This property is outstanding in every way..."

MainStay Suites Springfield South - Battlefield Rd

10/10 Excellent

"This hotel is nicely located, quite and the staff is VERY friendly and attentive."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"What a beautiful & stocked house! It truly is a home away from home. We loved the fenced yard for our dogs. Would definitely rent this property again!!"

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Good location and beautiful home."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Spacious house and very well maintained. Host was very responsive on answering our questions. We do an annual family reunion and this worked very well for us. Would definitely stay here again while in the area."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Extended Stay America Select Suites Springfield South is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and in-room kitchens. It's located just a short 0.5 mi (0.9 km) from Lester E. Cox Medical Center South. Other good choices close by include Residence Inn by Marriott Springfield and The Bradford Hotel, an Ascend Collection Hotel.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 21 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Find hotels near Lester E. Cox Medical Center South, Springfield from SAR 346

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Element by Marriott Springfield South

5. Candlewood Suites Springfield-Medical District

6. Hilton Garden Inn Springfield, MO

7. Residence Inn by Marriott Springfield

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Hampton Inn Springfield-Southeast

16. SpringHill Suites by Marriott Springfield North

17. Holiday Inn Express & Suites Springfield North by IHG

18. Walnut Street Inn

19. Home2 Suites by Hilton Springfield North

20. Drury Inn & Suites Springfield, MO

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Element by Marriott Springfield South

Sleep Inn Springfield South I60 near Medical District

The Bradford Hotel, an Ascend Collection Hotel

Hampton Inn Springfield-South

Residence Inn by Marriott Springfield

MainStay Suites Springfield South - Battlefield Rd

Peaceful Retreat near Medical Mile in Springfield

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Frequently asked questions