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Check prices for these dates

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14 Nov - 15 Nov
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15 Nov - 16 Nov
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20 Nov - 22 Nov
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Our top choices for Kentucky Science Center hotels

A wooden staircase with a balustrade leading to a landing.

1. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Kentucky Science Center
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is SARĀ 830
SARĀ 938 total
includes taxes & fees
15 Nov - 16 Nov
Market Street Inn
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.6 out of 10, Exceptional, (520 reviews)
"Excellent location and room!"
United States
Athina
The price is SARĀ 756
SARĀ 890 total
includes taxes & fees
26 Nov - 27 Nov
Hotel Distil, Autograph Collection
A grand hotel lobby with ornate ceiling designs, a central staircase, and a dining area.

3. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,489 reviews)
"Beautiful hotel!"
United States
Brianne
The price is SARĀ 400
SARĀ 471 total
includes taxes & fees
23 Nov - 24 Nov
The Brown Hotel
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

4. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.4 out of 10, Exceptional, (2,237 reviews)
"Very very nice property clean well taken care of and great staff would stay again"
United States
James
The price is SARĀ 667
SARĀ 785 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice hotel"
United States
Jeanette
The price is SARĀ 428
SARĀ 503 total
includes taxes & fees
24 Nov - 25 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

6. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is SARĀ 557
SARĀ 655 total
includes taxes & fees
23 Nov - 24 Nov
The Grady
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

7. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from Kentucky Science Center
9.6 out of 10, Exceptional, (152 reviews)
"Great staff, clean rooms, amazing historic vibe, and yummy breakfast!"
United States
Chris
The price is SARĀ 563
SARĀ 654 total
includes taxes & fees
28 Nov - 29 Nov
DuPont Mansion Bed & Breakfast
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

8. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Kentucky Science Center
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is SARĀ 409
SARĀ 671 total
includes taxes & fees
19 Nov - 20 Nov
Stellar Suites
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

9. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,159 reviews)
"Great stay!"
United States
Addison
The price is SARĀ 382
SARĀ 449 total
includes taxes & fees
25 Nov - 26 Nov
Tempo By Hilton Louisville Downtown Nulu
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

10. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Kentucky Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is SARĀ 571
SARĀ 691 total
includes taxes & fees
6 Dec - 7 Dec
21c Museum Hotel Louisville
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

11. Hotel BourrƩ Bonne Louisville, Curio Collection by Hilton

Hotel BourrƩ Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.4 out of 10, Exceptional, (179 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is SARĀ 551
SARĀ 648 total
includes taxes & fees
29 Nov - 30 Nov
Hotel BourrƩ Bonne Louisville, Curio Collection by Hilton
A modern bar area with a circular bar, multiple seating options, and a large screen.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,016 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is SARĀ 357
SARĀ 420 total
includes taxes & fees
13 Dec - 14 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
An outdoor seating area with wicker furniture and a fire pit.

13. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Kentucky Science Center
9.2 out of 10, Wonderful, (830 reviews)
"Nice stay, bed was comfortable"
United States
Brandi
The price is SARĀ 364
SARĀ 428 total
includes taxes & fees
29 Nov - 30 Nov
Towneplace Suites By Marriott Louisville Downtown
A covered patio with a stone wall, a glass table, and a bench.

14. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Kentucky Science Center
9.4 out of 10, Exceptional, (102 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is SARĀ 635
SARĀ 736 total
includes taxes & fees
18 Nov - 19 Nov
Central Park Bed & Breakfast
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

15. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.2 out of 10, Wonderful, (864 reviews)
"Amazing staff and location!!"
United States
Priscilla
The price is SARĀ 417
SARĀ 490 total
includes taxes & fees
14 Dec - 15 Dec
Moxy Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

16. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,003 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is SARĀ 459
SARĀ 540 total
includes taxes & fees
25 Nov - 26 Nov
Aloft by Marriott Louisville Downtown
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

17. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Kentucky Science Center
9.2 out of 10, Wonderful, (1,083 reviews)
"Gorgeous, clean room. Great onsite coffee shop and restaurant."
United States
Brittney
The price is SARĀ 537
SARĀ 632 total
includes taxes & fees
19 Nov - 20 Nov
Hotel Genevieve part of JdV by Hyatt
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

18. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Kentucky Science Center
9.2 out of 10, Wonderful, (733 reviews)
"Great location, helpful staff, and nice clean rooms,"
United States
Kevin
The price is SARĀ 537
SARĀ 632 total
includes taxes & fees
21 Nov - 22 Nov
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Kentucky Science Center
9.0 out of 10, Wonderful, (4,506 reviews)
"Great place to stay!!!"
United States
Shun
The price is SARĀ 486
SARĀ 572 total
includes taxes & fees
23 Nov - 24 Nov
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

20. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Kentucky Science Center
9.0 out of 10, Wonderful, (1,389 reviews)
"Enjoyed my whole stay, staff was friendly and helpful"
United States
Ernest P
The price is SARĀ 459
SARĀ 540 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Kentucky Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
520 reviews
View
A grand hotel lobby with ornate ceiling designs, a central staircase, and a dining area.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,489 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,237 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,004 reviews
View

Hotels recommended for families near Kentucky Science Center

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,506)
The price is SARĀ 486
SARĀ 572 total
includes taxes & fees
23 Nov - 24 Nov
Galt House Hotel Trademark Collection by Wyndham

Other attractions near Kentucky Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
See properties

Top Kentucky Science Center Hotel Reviews

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville

10/10 Excellent

Nice hotel
United States
Jeanette
Reviewed November 9, 2026
Homewood Suites by Hilton Louisville Downtown, KY

Frequently Asked Questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.

Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?

For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.