East Main Street, CO
Grand Junction


Visit East Main Street
Popular places to visit

Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and lively bars in this family-friendly area.
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its wineries.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its top-notch restaurants.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and top-notch restaurants in this family-friendly area.
Bananas Fun Park
Enjoy a fun-filled day at Bananas Fun Park during your trip to Grand Junction. Check out the notable monuments and top-notch restaurants in this family-friendly area.
East Main Street Hotel Deals

Grand Junction Vacation Rental w/ Fire Pit!
Beautiful home! Super clean, spacious, wonderful place to stay. My family enjoyed it so much they wany to go back. Fit our needs perfectly.
Reviewed on 22 December 2025

Launch your Colorado adventures – Historic Downtown convenience

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Great house and even a greater location! We could walk to all activities on Main St. House was very comfortable and we certainly enjoyed the hot tub after a day out visiting all the wineries, shopping, and great food! Thanks to our host, Ron, that answered all my questions!
Reviewed on 3 March 2026

Grand Lodge Close to Downtown
The listing omitted to fact a downstairs apartment was occupied. Thus we did not have the property to ourselves. The listing should have reflected the the basement apartment.
Reviewed on 24 December 2025

Grand Vista Hotel
The rooms are definitely what you pay for, it was me and my fiances first time solo traveling and i thought i just got lucky with a good deal but soon realized why it was so cheap. The rooms are smelly and broken, and while the iverall staff was nice upper management had no good customer servuce ...
Reviewed on 2 March 2026

La Quinta Inn & Suites by Wyndham Grand Junction
Staff was very friendly. Clean and quiet rooms. Breakfast staff very nice- breakfast itself was ok
Reviewed on 3 March 2026
Other neighborhoods around East Main Street

Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.

Washington Park
While Washington Park isn't home to many top sights, Western Colorado Center for the Arts and Western Colorado Botanical Gardens are some notable places to visit nearby.

7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Western Colorado Botanical Gardens, some noteworthy sights in the nearby area.

Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Center for the Arts and Western Colorado Botanical Gardens.

