The Best Hotels Closest to Florida Keys Eco - Discovery Center in Key West for 2026

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Our top choices for Florida Keys Eco - Discovery Center hotels

A modern hotel room with a large bed, a nightstand, a bedside table, and a bathroom visible through an open door.

A breakfast table with various food items and drinks, a pool in the background, and a tiled wall.

A swimming pool with lounge chairs, surrounded by palm trees and greenery.

A reception area with a wooden herringbone wall, teal chairs, a wooden bench, and two framed sunset paintings.

1. Almond Tree Inn Hotel - Adults Only

Downtown Key West, 0.8 km from Florida Keys Eco - Discovery Center

John

SAR 827

SAR 930 total

includes taxes & fees

12 Oct - 13 Oct

A tropical outdoor area with palm trees, hanging plants, and string lights.

A large, two-story building with a balcony, surrounded by dense tropical foliage.

A wooden deck with lush greenery and a pool area.

An outdoor patio with a table and chairs, surrounded by lush greenery and string lights.

2. Douglas House - Adults Only

Uptown - Upper Duval, 0.8 km from Florida Keys Eco - Discovery Center

Maricela

SAR 561

SAR 695 total

includes taxes & fees

12 Oct - 13 Oct

A modern interior with a staircase, a sofa set, a wooden table, and a television.

A spacious room with a large bed, a sofa, a chair, a small table, and a television.

A pathway flanked by lush green foliage leading to a gated entrance.

A courtyard with two green lounge chairs, a palm tree, and a building with a white facade and lattice window design.

3. Simonton Court Historic Inn & Cottages

Historic Seaport, 0.9 km from Florida Keys Eco - Discovery Center

William

SAR 860

SAR 968 total

includes taxes & fees

12 Oct - 13 Oct

A pool area with lounge chairs and a table, surrounded by palm trees.

A neon sign for Orchid Key Inn with a 'VACANCY' sign below it.

A building with a neon sign that reads "Orchid Key Inn."

A hotel room with a large bed, a nightstand, a desk, a bathroom with a shower, and a painting of a pier over water on the wall.

4. Orchid Key Inn - Adults Only

Uptown - Upper Duval, 0.7 km from Florida Keys Eco - Discovery Center

ben

SAR 870

SAR 979 total

includes taxes & fees

12 Oct - 13 Oct

A modern hotel room with a white sofa, a zebra-patterned rug, and a large mirror above the sofa.

A spacious living room with a wooden ceiling, white sofas, a patterned armchair, a glass coffee table, and a large painting on the wall.

A pool area with lounge chairs, a pool, and a building with a balcony and outdoor seating.

A spacious living room with a sofa, chairs, and a dining table. There are large windows with blinds, a door leading to a patio, and a ceiling with exposed beams.

5. Alexander's Guesthouse - Adult Exclusive

Old Town Key West, 1.6 km from Florida Keys Eco - Discovery Center

Nestor

SAR 808

SAR 1,063 total

includes taxes & fees

12 Oct - 13 Oct

A porch with a white railing, a bench, and a flag.

A spacious bedroom with a large bed, a sitting area with a sofa and armchairs, and a dining area with a table and chairs.

A two-story white house with green shutters, a wooden door, and a white picket fence.

A living room with a sofa, a glass coffee table, a TV, and a painting on the wall.

6. The Conch House Heritage Inn

Old Town Key West, 1 km from Florida Keys Eco - Discovery Center

John

SAR 892

SAR 1,004 total

includes taxes & fees

12 Oct - 13 Oct

A garden pathway leading to a white gazebo with pink flowers, surrounded by lush greenery and a white fence.

A bar area with a counter, chairs, and a clock.

A couple walking along a poolside pathway surrounded by lush greenery.

A colonial-style building with a porch, surrounded by lush tropical vegetation.

7. The Gardens Hotel

Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center

Gisele

SAR 1,263

SAR 1,421 total

includes taxes & fees

14 Oct - 15 Oct

A gated entrance to Villas Key West with a brick pathway leading to the gate.

A house with a porch, a table, and a door with a number '6'.

A swimming pool with a hot tub, surrounded by a wooden deck and lush greenery.

A covered entrance with a brick pathway leading to a gated area, surrounded by lush greenery and plants.

8. Key West Villas

Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center

Margaret

SAR 977

SAR 1,099 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with a bed, a desk, a chair, a ceiling fan, a nightstand, and a window with a view of plants and a patio.

A poolside area with a swimming pool, a staircase leading to a deck, and a building with multiple windows and balconies.

A two-story house with a covered porch, a brick pathway, and a large tree.

A covered porch with white wicker furniture and a blue floor, surrounded by lush tropical plants.

9. The Marquesa Hotel

Old Town Key West, 0.8 km from Florida Keys Eco - Discovery Center

Darrell

SAR 1,273

SAR 1,644 total

includes taxes & fees

12 Oct - 13 Oct

A wooden deck with white railings, surrounded by lush greenery and a staircase leading to a building.

A two-story building with a white picket fence, a mailbox, and a small tree in front.

A lush garden with a variety of tropical plants and a paved walkway.

A swimming pool with a mural of a dolphin and a butterfly, surrounded by lounge chairs and palm trees.

10. Duval House

Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center

Cliff

SAR 665

SAR 829 total

includes taxes & fees

25 Oct - 26 Oct

A wooden deck with a hammock, pool, and lounge chairs overlooking a tropical garden.

A covered walkway with a wooden ceiling, white railings, and a brick path.

A pool area with lounge chairs and a wooden building with balconies.

A compact kitchen with wooden cabinets, a microwave, stove, and refrigerator. There is a dining area with a table and chairs, and a sofa.

11. Island City House Hotel

Historic Seaport, 1.1 km from Florida Keys Eco - Discovery Center

Osvaldo

SAR 838

SAR 943 total

includes taxes & fees

25 Oct - 26 Oct

A narrow outdoor pathway flanked by potted plants and a wooden staircase leading to a white door with shutters.

A two-story building with a porch, a sign reading "The Grand Guesthouse," and a purple flag.

A row of blue bicycles parked under a tree, with a white fence and a building in the background.

A covered outdoor area with a wooden staircase, seating, and potted plants.

12. The Grand Guesthouse

Old Town Key West, 1.5 km from Florida Keys Eco - Discovery Center

Justyn

SAR 448

SAR 598 total

includes taxes & fees

13 Oct - 14 Oct

A pool area with lounge chairs and palm trees.

A sign for Santa Maria Resort surrounded by lush greenery and palm trees.

A neatly made bed with patterned pillows, a bedside table with a bottle and glasses, and a window with orchids.

A modern outdoor seating area with a sofa, chairs, and a small table, surrounded by glass doors and a view of greenery.

13. Santa Maria Suites

Uptown - Upper Duval, 1.2 km from Florida Keys Eco - Discovery Center

Anthony

SAR 1,160

SAR 1,559 total

includes taxes & fees

25 Oct - 26 Oct

A room with a bed, a ceiling fan, and a window with blinds.

A spacious kitchen with wooden cabinets, a granite countertop, and a ceiling fan.

A cozy outdoor seating area with a wooden bench and a table, surrounded by potted plants and a coffee and tea sign.

A room with a yellow armchair, a glass coffee table, and a view of a wooden deck and tropical plants.

14. The Mermaid & Alligator

Old Town Key West, 1.1 km from Florida Keys Eco - Discovery Center

Adam

SAR 946

SAR 1,065 total

includes taxes & fees

12 Oct - 13 Oct

A large, ornate hotel with a pool, palm trees, and a view of the ocean.

A balcony with white railings and a table, overlooking a beach with palm trees and a clear blue sky.

A grand staircase with ornate railings and a chandelier.

A gated entrance with a blue metal gate, palm trees, and a building with a red roof in the background.

15. Southernmost House - Adult Exclusive

Uptown - Upper Duval, 1.1 km from Florida Keys Eco - Discovery Center

Amy

SAR 523

SAR 1,064 total

includes taxes & fees

25 Oct - 26 Oct

A swimming pool with water splashing, surrounded by palm trees and a building in the background.

A hotel with a pool, bicycles, and lush greenery.

The entrance to Silver Palms Inn with a reception desk, a seating area, and a glass door.

The exterior of the Silver Palms Inn with a two-story structure, a green awning over the entrance, and a palm tree to the right.

16. Silver Palms Inn & Historic Homes

Old Town Key West, 1.2 km from Florida Keys Eco - Discovery Center

sam

SAR 335

SAR 630 total

includes taxes & fees

25 Oct - 26 Oct

A reception area with a curved marble counter, ceiling fans, large windows, and a staircase.

A breakfast table with a variety of food items, including fruits, pastries, and a coffee mug.

A bedroom with a bed, two bedside lamps, a ceiling fan, and a view of a balcony with plants.

A two-story house with a white exterior, a green roof, and a staircase leading to the upper floor.

17. Westwinds Inn

Historic Seaport, 1.3 km from Florida Keys Eco - Discovery Center

Anthony

SAR 608

SAR 684 total

includes taxes & fees

12 Oct - 13 Oct

A gated entrance with lush green foliage and a white picket fence.

A covered outdoor dining area with white chairs and tables, surrounded by lush greenery and a wooden deck.

A hotel room with a large bed, two bedside tables, a ceiling fan, and two framed pictures on the wall.

A swimming pool with lounge chairs, a covered deck, and a view of lush greenery.

18. Coco Plum Inn

Downtown Key West, 0.5 km from Florida Keys Eco - Discovery Center

Riley

SAR 710

SAR 799 total

includes taxes & fees

12 Oct - 13 Oct

A rectangular pool with a white deck, surrounded by lush greenery and a gazebo.

A wicker outdoor seating area with two chairs and a table, surrounded by lush tropical foliage.

A spacious living room with a high ceiling, a ceiling fan, a large painting, a sofa, a coffee table, and a dining area with a table and chairs.

A cozy living room with a wooden ceiling, a sofa set, two side tables with lamps, and framed artwork on the wall.

19. Ambrosia Key West

Old Town Key West, 0.9 km from Florida Keys Eco - Discovery Center

Tricia

SAR 714

SAR 803 total

includes taxes & fees

12 Oct - 13 Oct

A poolside area with lounge chairs, umbrellas, and a pergola.

A wooden bench with a cushion and a small table, surrounded by bamboo plants and a wooden deck.

A bright kitchen with white cabinetry, a white island, wicker pendant lights, and geometric patterned backsplash.

A living room with a spiral staircase, a sofa, a chair, a coffee table, and a view of an outdoor seating area.

20. Ella's Cottages - Key West Historic Inns

Old Town Key West, 0.8 km from Florida Keys Eco - Discovery Center

Henry

SAR 939

SAR 1,246 total

includes taxes & fees

12 Oct - 13 Oct

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Compare popular hotels close to Florida Keys Eco - Discovery Center

Property	Property class	Guest rating
Almond Tree Inn Hotel - Adults Only	10.0 Exceptional 1,000 reviews	View
Douglas House - Adults Only	9.8 Exceptional 552 reviews	View
Simonton Court Historic Inn & Cottages	9.8 Exceptional 1,003 reviews	View
Orchid Key Inn - Adults Only	9.8 Exceptional 1,002 reviews	View
Alexander's Guesthouse - Adult Exclusive	9.8 Exceptional 171 reviews	View

Top Florida Keys Eco - Discovery Center Hotel Reviews

Winslow's Bungalows - Key West Historic Inns

10/10 Excellent

"Very cute and clean place to stay"

Weatherstation Inn

10/10 Excellent

"We liked how close the Inn was to everything we wanted to do. Very walkable and in a quiet area. Staff was friendly, the breakfast bake goods were great."

Duval House

10/10 Excellent

"Great breakfast in the morning and cheap beers at the front desk. (Except they ran out of Bud Light) Great stay Oct 6th-10th. Pool was cool and refreshing after walking in the heat all morning/afternoon. A great way to refresh and rejuvenate for dinner or evening plans. DH feels like a secluded hideaway."

Tranquility Guest House

10/10 Excellent

"Lived up to its name-very tranquil. Well decorated interior with an ‘old Key West vibe’ but with updated modern bathroom. Nice pool area retreat. Location was perfect-walking distance to all major Key West attractions, restaurants, park, etc. This would be first on our list for a return visit!"

Lighthouse Hotel - Key West Historic Inns

10/10 Excellent

"Location, location, location. Nice, clean place to stay, walkable to Duval Street. No car needed."

Southwinds Motel

10/10 Excellent

"Close to a lot of places I wanted to see. The ice cream and doughnuts bar was awesome! The was really comfortable."

The Cabana Inn Key West - Adults Only

10/10 Excellent

"Our room was spacious and clean. We loved the uniqueness of the hotel and the proximity to all the bars and restaurants on Duvall street."

La Concha Key West, Autograph Collection

10/10 Excellent

"Wonderful place at a great location"

Historic Old Town Key West Cigarmaker's Cottage - Cigar House, Sleeps 4

10/10 Excellent

"The cottage, pool, hotub, and gardens were delightful. Felt very secluded right in the middle of Old Town. So convenient to walk to so many places. The cottage decor is decidedly Key West and so much fun. We had a great week celebrating our 40th anniversary - it was perfect."

Other attractions near Florida Keys Eco - Discovery Center

A coastal fortification with a staircase leading to a higher platform, overlooking the sea.

Fort Zachary Taylor Historic State Park

9.0/10 (4,544 reviews)

Enjoy a trip to Fort Zachary Taylor Historic State Park and popular activities like boating in Key West. Discover the area's beautiful sunsets, or seek out its biking trails.

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The Monroe County Courthouse with a clock tower, surrounded by trees and a clear blue sky.

Jackson Square

8.8/10 (110 reviews)

You can learn about the history of Key West with a stop at Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.

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A white lighthouse with a black top, surrounded by lush greenery and residential buildings.

Key West Lighthouse and Keeper's Quarters Museum

8.6/10 (548 reviews)

You can spend time exploring the galleries in Key West Lighthouse and Keeper's Quarters Museum in Key West. Amble around the area's seaside or seek out the biking trails.

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Florida Keys National Marine Sanctuary

9.0/10 (112 reviews)

Enjoy a trip to Florida Keys National Marine Sanctuary and popular activities like boating in Key West. In the area, take in the lively festivals and beautiful sunsets.

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Truman Waterfront Park

You can take time to visit Truman Waterfront Park during your travels to Key West. Discover the area's lively bars and its entertainment choices.

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USCGC Ingham Maritime Museum

You can spend an afternoon exploring the galleries in USCGC Ingham Maritime Museum during your trip to Key West.

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Coffee Butler Amphitheater

You can enjoy a show at Coffee Butler Amphitheater during your trip to Key West. Discover the area's lively bars and its entertainment choices.

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We Cycle Key West

You can search for that perfect souvenir at We Cycle Key West during your trip to Key West.

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Frequently asked questions

What's the area like around Florida Keys Eco - Discovery Center?

Florida Keys Eco - Discovery Center is located in an area of Key West known for its beautiful ocean views, bar scene, and lively festivals. If you're looking for a convenient place to stay, check out the 1558 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Florida Keys Eco - Discovery Center?

Adjacent to Florida Keys Eco - Discovery Center, Tranquility Guest House is one of the top choices for your stay based on our traveler data, and this hotel offers an outdoor pool and free WiFi. Other good choices close by include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.

How many hotels will I be able to find close to Florida Keys Eco - Discovery Center?

Expedia has 1558 hotels and other accommodations within a mile from Florida Keys Eco - Discovery Center.

If I need to cancel the hotel reservation for my stay near Florida Keys Eco - Discovery Center, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view the best options available near Florida Keys Eco - Discovery Center.

Where can I learn more about changing or cancelling my trip in the area near Florida Keys Eco - Discovery Center?

For more information about changing or cancelling your stay near Florida Keys Eco - Discovery Center, head over to our customer service page.

What can I see and do near Florida Keys Eco - Discovery Center?

Study the collections at Key West Lighthouse and Keeper's Quarters Museum, Ernest Hemingway Home and Museum, or Harry S. Truman Little White House. While you're exploring, swing by Fort Zachary Taylor Historic State Park, Fort East Martello Museum and Gallery, and Audubon House and Tropical Gardens to learn a bit about the area. You can catch a show at Red Barn Theater, Coffee Butler Amphitheater, and Key West Film Society.

Find hotels near Florida Keys Eco - Discovery Center, Key West from SAR 598

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Our top choices for Florida Keys Eco - Discovery Center hotels

1. Almond Tree Inn Hotel - Adults Only

2. Douglas House - Adults Only

3. Simonton Court Historic Inn & Cottages

4. Orchid Key Inn - Adults Only

5. Alexander's Guesthouse - Adult Exclusive

6. The Conch House Heritage Inn

7. The Gardens Hotel

8. Key West Villas

9. The Marquesa Hotel

10. Duval House

11. Island City House Hotel

12. The Grand Guesthouse

13. Santa Maria Suites

14. The Mermaid & Alligator

15. Southernmost House - Adult Exclusive

16. Silver Palms Inn & Historic Homes

17. Westwinds Inn

18. Coco Plum Inn

19. Ambrosia Key West

20. Ella's Cottages - Key West Historic Inns

Compare popular hotels close to Florida Keys Eco - Discovery Center

Top Florida Keys Eco - Discovery Center Hotel Reviews

Winslow's Bungalows - Key West Historic Inns

Weatherstation Inn

Duval House

Tranquility Guest House

Lighthouse Hotel - Key West Historic Inns

Southwinds Motel

The Cabana Inn Key West - Adults Only

La Concha Key West, Autograph Collection

Historic Old Town Key West Cigarmaker's Cottage - Cigar House, Sleeps 4

Other attractions near Florida Keys Eco - Discovery Center

Fort Zachary Taylor Historic State Park

Jackson Square

Key West Lighthouse and Keeper's Quarters Museum

Florida Keys National Marine Sanctuary

Truman Waterfront Park

USCGC Ingham Maritime Museum

Coffee Butler Amphitheater

We Cycle Key West

Frequently asked questions