Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and notable monuments in this vibrant area.
Brancacci Chapel
You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Cathedral of Santa Maria del Fiore
Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.
Ponte Vecchio
Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the notable monuments and stunning cathedral in this vibrant area.
Santo Spirito Hotel Deals
Hotel Horto Convento
Extremely clean and modern, beautiful historic setting
Reviewed on 31 March 2026
Palazzo Mannaioni Suites
I had a great stay at this hotel. Everything was excellent—from the convenient location to the cleanliness and the spacious room size. It made my trip very comfortable, and I would definitely stay here again. Just need some work in Wi Fi
Reviewed on 3 April 2026
Foresteria Valdese di Firenze - Casa per Ferie
We had to leave early morning and hot water wasn't available until later in the morning around 6 or 6:30 am. There is only 1 mirror which is in the bathroom and creates some inconvenience while getting ready. Location is good and stay was pleasant.
Reviewed on 5 April 2026
UNA Hotels Vittoria Firenze
Helpful staff. Vey good breakfast. Clean and comfortable room.
Reviewed on 1 April 2026
La Torre Del Cestello
Perfect little room in Florence. Walkable to everything.
Reviewed on 4 April 2026
Palazzo Oliveto
The room was not that clean, there was mold on the shower, there were some stains on the wall. The higienic part of the overall room is the reason why I give 2.
Reviewed on 10 November 2025
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
Historic Centre of Florence
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral, and stunning river views.
Duomo
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
