Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

4/5(14 reviews)

Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its acclaimed art scene.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

You can learn about the history of Florence with a stop at Brancacci Chapel. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Brancacci Chapel
Uffizi Gallery

Uffizi Gallery

4.5/5(1,486 reviews)

Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Uffizi Gallery
Ponte Vecchio which includes a bridge and a river or creek

Ponte Vecchio

4.5/5(2,057 reviews)

Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the churches and notable monuments in this vibrant area.

Ponte Vecchio
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

4.5/5(1,301 reviews)

Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Cathedral of Santa Maria del Fiore

Santo Spirito Hotel Deals

UNA HOTELS Vittoria Firenze

UNA HOTELS Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
The price is SAR 436 per night from Jul 27 to Jul 28
SAR 436
SAR 541 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (986 reviews)
"It was average really. Needs to be updated in the rooms blobby area and outside was very nice"

Reviewed on 31 May 2025

UNA HOTELS Vittoria Firenze
Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
The price is SAR 581 per night from Jul 27 to Jul 28
SAR 581
SAR 700 total
27 Jul - 28 Jul
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (541 reviews)
"Staff were very helpful and professional. Speaking English was not a problem. The breakfast buffet had a lot fresh food, fruit and pastries to choose from"

Reviewed on 7 July 2025

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,002 reviews)
"Great experience overall!"

Reviewed on 11 July 2025

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Palazzo Mannaioni Suites
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49, Florence, FI
Fully refundableReserve now, pay when you stay
The price is SAR 289 per night from Jul 29 to Jul 30
SAR 289
SAR 371 total
29 Jul - 30 Jul
includes taxes & fees
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (152 reviews)
"A traditional street near the river so perfect for Ufizzi and centre of Florence Lovely building with a lovely feel to it Friendly reception/ helpful ( parking not so easy and penalty fine on its way to is for coming to hotel in car)"

Reviewed on 4 July 2025

Foresteria Valdese di Firenze - Casa per Ferie
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8, Florence, FI
The price is SAR 451 per night from Aug 5 to Aug 6
SAR 451
SAR 549 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (193 reviews)
Perfect spot
"Amazing room, we were on the first floor and had very tall ceilings in a very cool building. Safe area and secure building as well. Highly recommend"

Reviewed on 21 July 2025

La Torre Del Cestello
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (309 reviews)
"This was a great historical property that was once owned by a prominent family. We stayed in the room advertised for a family of five. We had 5 comfortable twin beds and a large bathroom with a double sink. Air conditioner worked well and room was dark when needed to be. Lovely large garden in back ..."

Reviewed on 23 July 2025

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Casa Santo Nome di Gesù
See all 468 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Palazzo dei Congressi is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence

Santo Spirito

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