East Prairie, MO
Travel Guide
Visit East Prairie
Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
The price is SAR 334 per night from Jul 6 to Jul 7
SAR 334
SAR 380 total
6 Jul - 7 Jul
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,003 reviews)
"Friendly"
Reviewed on 23 June 2025
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
The price is SAR 382 per night from Jul 10 to Jul 11
SAR 382
SAR 440 total
10 Jul - 11 Jul
includes taxes & fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
Nice place to stop.
"Nice, clean hotel. It’s a very small town, but there is fast food nearby and close to the interstate. We made a quick one night stop but enjoyed the indoor/outdoor pool and indoor hot tub. The parking lot was very wel lit and the area felt safe."
Reviewed on 30 June 2025
Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
The price is SAR 337 per night from Jul 6 to Jul 7
SAR 337
SAR 388 total
6 Jul - 7 Jul
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,006 reviews)
"Very clean room and pool and good breakfast!"
Reviewed on 30 June 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Reelfoot Lake are located ...
9.8/10 Exceptional! (194 reviews)
"House was very clean! Could have had privacy curtains/blinds at back of house. Other than that, everything was great!"
Reviewed on 14 June 2025
Charming A Frame house with WiFi in Union City
Union City
Stay at this vacation home in Union City. Enjoy laundry facilities and air conditioning. Popular attractions Discovery Park of America and County Market Place ...
10/10 Exceptional! (6 reviews)
"This is an adorable house! Super cozy but with all of the things a family would need for a comfortable stay. The host was impressively fast at answering messages, even when I had a question before I booked. She is probably one of the most responsive hosts I’ve encountered! We had 4 people in our ..."
Reviewed on 15 June 2025
Dancing Diamonds Waterfront Retreat
Tiptonville
Stay at this vacation home in Tiptonville. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Reelfoot Lake State Park and Campbell's Point ...
10/10 Exceptional! (85 reviews)
Great property
"Very quiet. Comfortable beds, Great location."
Reviewed on 15 February 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Big Oak Tree State Park
4.5/5(3 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
- Big Oak Tree State Park
- Mississippi River
- Ohio River
- Reelfoot Lake
- Discovery Park of America
- Reelfoot Lake State Park
- Columbus-Belmont State Park
- Union City Masquerade Theatre
- Fort Defiance State Park
- Graham Park
- Marston Community Center
- Sikeston Depot Museum
- Campbell's Point
- River Ridge Winery
- New Madrid Historical Museum
- Central Park
- Hunter-Dawson State Historic Site
- Front Street Studio & Art Gallery