Resorts & Hotels with Spas in Panama from SAR 409
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Panama Resorts & Hotels with Spas
Pick from 268 Panama Resorts & Hotels with Spas with updated room rates, reviews, and availability. Most hotels are fully refundable.

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
8.8 out of 10, Excellent, (960)
The price is SAR 559
SAR 615 total
includes taxes & fees
23 Jun - 24 Jun

Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
8.4 out of 10, Very Good, (2117)
The price is SAR 413
SAR 516 total
includes taxes & fees
28 Jun - 29 Jun

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (581)
The price is SAR 890
SAR 978 total
includes taxes & fees
28 Jun - 29 Jun

Marriott Panama Hotel
Marriott Panama Hotel
9.0 out of 10, Wonderful, (1004)
The price is SAR 504
SAR 554 total
includes taxes & fees
13 Jul - 14 Jul

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1000)
The price is SAR 657
SAR 723 total
includes taxes & fees
29 Jun - 30 Jun

W Panama
W Panama
8.8 out of 10, Excellent, (1005)
The price is SAR 658
SAR 723 total
includes taxes & fees
4 Jul - 5 Jul

Radisson Colon 2,000 Hotel & Casino
Radisson Colon 2,000 Hotel & Casino
8.0 out of 10, Very Good, (754)
The price is SAR 409
SAR 450 total
includes taxes & fees
20 Jun - 21 Jun

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (461)
The price is SAR 1,098
SAR 1,208 total
includes taxes & fees
18 Jun - 19 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Recent reviews of Panama hotels
Recent reviews of Panama hotels

Waymore Hotel Spa & Casino
5/5 Excellent
"This hotel actually looks like it does in pictures. The staff were very nice and accommodating. "
A verified traveler stayed at Waymore Hotel Spa & Casino
Posted 9 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top destinations for Resorts & Hotels with Spas in Panama
- Resorts & Hotels with Spas in Panamá Province
- Resorts & Hotels with Spas in Bocas del Toro Province
- Resorts & Hotels with Spas in Coclé
- Resorts & Hotels with Spas in Veraguas
- Resorts & Hotels with Spas in Chiriquí Province
- Resorts & Hotels with Spas in Colón
- Resorts & Hotels with Spas in Los Santos
- Resorts & Hotels with Spas in Herrera
More Hotel Options in Panama
- Hotels with WiFi in Panama
- Hotels with Free Parking in Panama
- Family Hotels in Panama
- Hotels with Bars in Panama
- Beach Hotels in Panama
- Hotels with a Pool in Panama
- Adventure Hotels in Panama
- Business Hotels in Panama
- Shopping Hotels in Panama
- Hotel with a Concierge in Panama
- Hotels with smoking rooms in Panama
- Historic Hotels in Panama
- Casinos in Panama
- Pet-friendly Hotels in Panama
- Hotel Wedding Venues in Panama
- Cheap Hotels in Panama
- Luxury Hotels in Panama
- Romantic Hotels in Panama
- Hotels with Hot Tubs in Panama
- Golf Hotels in Panama
More Themes
- All-inclusive Hotel
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Family Hotels
- Hotels with Free Parking
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Lazy River
- Luxury Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Romantic Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Green Hotels
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels
Stay near popular Panama attractions
Discover hotels close to Panama with room rates, reviews, and availability. Most hotels are fully refundable.
- Hotel Riu Plaza Panama
- Sheraton Grand Panama
- Dreams Playa Bonita Panama - All Inclusive
- Crowne Plaza Panama Airport by IHG
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Novotel Panama City
- Megapolis Hotel Panamá
- TRYP by Wyndham Panamá Centro
- Waymore Hotel Spa & Casino