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Our top choices for Florence County hotels

Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center AreaFlorence
9.2 out of 10, Wonderful, (1,215 reviews)
The price is SARĀ 368
SARĀ 412 total
includes taxes & fees
1 Mar - 2 Mar

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
8.6 out of 10, Excellent, (2,565 reviews)
The price is SARĀ 264
SARĀ 295 total
includes taxes & fees
5 Feb - 6 Feb

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCFlorence
9.0 out of 10, Wonderful, (2,252 reviews)
The price is SARĀ 317
SARĀ 355 total
includes taxes & fees
8 Feb - 9 Feb

Residence Inn Marriott Florence
Residence Inn Marriott FlorenceFlorence
8.8 out of 10, Excellent, (509 reviews)
The price is SARĀ 372
SARĀ 417 total
includes taxes & fees
10 Feb - 11 Feb

Hyatt Place Florence Downtown
Hyatt Place Florence DowntownFlorence
9.0 out of 10, Wonderful, (1,003 reviews)
The price is SARĀ 375
SARĀ 420 total
includes taxes & fees
23 Feb - 24 Feb

La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham FlorenceFlorence
8.0 out of 10, Very Good, (1,672 reviews)
The price is SARĀ 371
SARĀ 416 total
includes taxes & fees
8 Feb - 9 Feb

TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott FlorenceFlorence
9.0 out of 10, Wonderful, (749 reviews)
The price is SARĀ 395
SARĀ 443 total
includes taxes & fees
9 Feb - 10 Feb

Tru by Hilton Florence I-95
Tru by Hilton Florence I-95Florence
8.4 out of 10, Very Good, (1,004 reviews)
The price is SARĀ 351
SARĀ 406 total
includes taxes & fees
10 Feb - 11 Feb

Hilton Garden Inn Florence
Hilton Garden Inn FlorenceFlorence
8.6 out of 10, Excellent, (275 reviews)
The price is SARĀ 401
SARĀ 450 total
includes taxes & fees
15 Feb - 16 Feb

Home2 Suites by Hilton Florence, SC
Home2 Suites by Hilton Florence, SCFlorence
8.2 out of 10, Very Good, (1,004 reviews)
The price is SARĀ 397
SARĀ 444 total
includes taxes & fees
22 Feb - 23 Feb

Hampton Inn & Suites Florence-North-I-95
Hampton Inn & Suites Florence-North-I-95Florence
9.0 out of 10, Wonderful, (853 reviews)
The price is SARĀ 440
SARĀ 492 total
includes taxes & fees
11 Feb - 12 Feb

Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence CenterFlorence
9.0 out of 10, Wonderful, (850 reviews)
The price is SARĀ 412
SARĀ 462 total
includes taxes & fees
12 Feb - 13 Feb

Courtyard by Marriott Florence
Courtyard by Marriott FlorenceFlorence
7.8 out of 10, Good, (707 reviews)
The price is SARĀ 379
SARĀ 424 total
includes taxes & fees
9 Feb - 10 Feb

Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic CenterFlorence
7.8 out of 10, Good, (1,257 reviews)
The price is SARĀ 319
SARĀ 358 total
includes taxes & fees
5 Mar - 6 Mar

Staybridge Suites Florence - Civic Center by IHG
Staybridge Suites Florence - Civic Center by IHGFlorence
9.4 out of 10, Exceptional, (955 reviews)
The price is SARĀ 506
SARĀ 567 total
includes taxes & fees
8 Feb - 9 Feb

Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20Florence
9.2 out of 10, Wonderful, (582 reviews)
The price is SARĀ 411
SARĀ 461 total
includes taxes & fees
11 Feb - 12 Feb

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHGFlorence
9.2 out of 10, Wonderful, (1,000 reviews)
The price is SARĀ 428
SARĀ 479 total
includes taxes & fees
8 Feb - 9 Feb

SpringHill Suites by Marriott Florence
SpringHill Suites by Marriott FlorenceFlorence
8.6 out of 10, Excellent, (1,001 reviews)
The price is SARĀ 364
SARĀ 407 total
includes taxes & fees
8 Feb - 9 Feb

Microtel Inn & Suites by Wyndham Florence
Microtel Inn & Suites by Wyndham FlorenceFlorence
6.8 out of 10, (1,001 reviews)
The price is SARĀ 206
SARĀ 231 total
includes taxes & fees
8 Feb - 9 Feb

Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SCFlorence
7.8 out of 10, Good, (46 reviews)
The price is SARĀ 335
SARĀ 390 total
includes taxes & fees
10 Feb - 11 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals inĀ Florence County, SC
Showing deals for:13 Feb - 15 Feb
Image gallery for Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8/10Exceptional (42 reviews)
10% off
Price is SARĀ 624
SARĀ 1,831 total
includes taxes & fees
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