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30 Sep - 1 Oct
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1 Oct - 2 Oct
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2 Oct - 4 Oct
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9 Oct - 11 Oct

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Our top choices for Commerce hotels

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

1. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
SAR 380
SAR 428 total
includes taxes & fees
8 Oct - 9 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
SAR 372
SAR 423 total
includes taxes & fees
29 Oct - 30 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

3. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Elizabeth
SAR 270
SAR 305 total
includes taxes & fees
11 Oct - 12 Oct
Pear Tree Inn Cape Girardeau West
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
SAR 338
SAR 381 total
includes taxes & fees
5 Oct - 6 Oct
Drury Inn & Suites Cape Girardeau
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
SAR 375
SAR 424 total
includes taxes & fees
5 Oct - 6 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
An outdoor patio with stone walls, wicker furniture, and large windows.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
SAR 397
SAR 448 total
includes taxes & fees
8 Oct - 9 Oct
Hampton Inn Cape Girardeau I 55 East
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A hotel room with two beds, a nightstand, a lamp, and a chair.

7. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
SAR 303
SAR 328 total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

8. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
SAR 386
SAR 436 total
includes taxes & fees
12 Oct - 13 Oct
The Riverview
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
SAR 336
SAR 382 total
includes taxes & fees
8 Oct - 9 Oct
Tru By Hilton Cape Girardeau
A hotel lobby with a reception desk, seating area, and a large window.
A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.
A hotel room with a desk, chair, television, and a lamp.
A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

10. Quality Inn Cairo I-57

Quality Inn Cairo I-57
Cairo
United States
Santiago
SAR 256
SAR 284 total
includes taxes & fees
16 Oct - 17 Oct
Quality Inn Cairo I-57
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

11. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
SAR 470
SAR 532 total
includes taxes & fees
15 Oct - 16 Oct
Courtyard by Marriott Cape Girardeau Downtown
A building with a fountain and flower beds in front.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

12. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Kathleen
SAR 250
SAR 277 total
includes taxes & fees
3 Oct - 4 Oct
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.
A reception area with a counter, a flat-screen TV, and a window with blinds.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

13. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
SAR 223
SAR 248 total
includes taxes & fees
4 Oct - 5 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

14. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
SAR 353
SAR 406 total
includes taxes & fees
29 Oct - 30 Oct
Drury Inn & Suites Sikeston, MO
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel room with a bed, a TV, a desk, and a chair.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

15. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
SAR 319
SAR 381 total
includes taxes & fees
11 Oct - 12 Oct
Candlewood Suites Cape Girardeau by IHG
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.
A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

16. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
SAR 284
SAR 307 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Jackson-Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

17. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Danny
SAR 223
SAR 252 total
includes taxes & fees
1 Nov - 2 Nov
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

18. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
SAR 263
SAR 307 total
includes taxes & fees
2 Oct - 3 Oct
Town House Inn Cape Giradreau
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.
A motel with a sign reading "Eagle Inn" and a parking lot with several cars.
A bathroom with a sink, mirror, towel rack, shower, and toilet.

19. Eagle Inn Charleston

Eagle Inn Charleston
Charleston
United States
Jackson
SAR 248
SAR 275 total
includes taxes & fees
2 Oct - 3 Oct
Eagle Inn Charleston
A hotel room with two beds, a desk, a chair, a TV, and a mirror.
A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.
A reception area with a counter, a coffee machine, and seating.
A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

20. Country Yard Inn and Suite

Country Yard Inn and Suite
Sikeston
United States
William
SAR 212
SAR 252 total
includes taxes & fees
2 Oct - 3 Oct
Country Yard Inn and Suite
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Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"EVERYONE was EXTREMELY FRIENDLY"
Rex 1-night trip
Posted 1 hour ago
Drury Inn & Suites Sikeston, MO
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"No complaints"
Don 3-night trip
Posted 7 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

10/10 Excellent
"Great place great breakfast great room staff was great"
Jim 1-night trip
Posted 14 hours ago
Quality Inn Cape Girardeau North
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent
"trodo estubo excelente gracias por sus servicios"
Julio 1-night trip
Posted 2 days ago
Candlewood Suites Cape Girardeau by IHG
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent
"Clean rooms. Nice breakfast. Very nice staff."
Teresa 1-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."
Christy 2-night trip
Posted 3 days ago
Drury Inn & Suites Cape Girardeau
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."
Valarie 2-night trip
Posted 3 days ago
Hampton Inn Cape Girardeau I 55 East
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."
Sheila and keith 1-night trip
Posted 5 days ago
Courtyard by Marriott Cape Girardeau Downtown
Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

10/10 Excellent
"Super communication! . Accommodating. Nice people"
JASEN 2-night trip
Posted 2 weeks ago
Cozy cabins on beautiful Horseshoe Lake

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO
SAR 223
SAR 248 total
4 Oct - 5 Oct
includes taxes & fees
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO
SAR 223
SAR 252 total
1 Nov - 2 Nov
includes taxes & fees
7/10 Good! (801 reviews)
Quality Inn Cape Girardeau North
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
SAR 270
SAR 305 total
11 Oct - 12 Oct
includes taxes & fees
Pear Tree Inn Cape Girardeau West
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO
SAR 319
SAR 381 total
11 Oct - 12 Oct
includes taxes & fees
8/10 Very Good! (1,002 reviews)
Candlewood Suites Cape Girardeau by IHG
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO
SAR 336
SAR 382 total
8 Oct - 9 Oct
includes taxes & fees
Tru By Hilton Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
SAR 372
SAR 423 total
29 Oct - 30 Oct
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

What's the best place to stay in Commerce?
Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in Commerce.
What are some of the best vacation home rentals in Commerce?
3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This vacation home rental near Commerce is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Commerce.
If I need to cancel my hotel reservation in Commerce, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.
Where can I learn more about changing or cancelling my trip to Commerce?
To find more details about rescheduling or cancelling your trip to Commerce, go to https://www.expedia.com/service/.
What's it like to stay in Commerce?
Travelers to Commerce will find plenty to explore and enjoy. There are 88 hotels and other accommodations in the surrounding area. Find out more about Commerce.
What is there to see in Commerce?
A favorite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Check out what more to see and do in Expedia's Commerce guide.
What's the weather like in Commerce?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Commerce is 59 inches.