Photo by Molly Bond
Find Business Hotels in Clarksdale, MS
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Clarksdale Business Hotels
Top Clarksdale Business Hotels

Hampton Inn Clarksdale
Hampton Inn Clarksdale
8.2 out of 10, Very Good, (291)
The price is SAR 443
SAR 483 total
includes taxes & fees
6 Jul - 7 Jul

Americas Best Value Inn & Suites Clarksdale
Americas Best Value Inn & Suites Clarksdale
5.8 out of 10, (364)
The price is SAR 285
SAR 311 total
includes taxes & fees
1 Jul - 2 Jul

Holiday Inn Express Hotel & Suites Cleveland by IHG
Holiday Inn Express Hotel & Suites Cleveland by IHG
7.8 out of 10, Good, (882)
The price is SAR 559
SAR 609 total
includes taxes & fees
1 Jul - 2 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Clarksdale hotels
Recent reviews of Clarksdale hotels

Quality Inn
5/5 Excellent
"Great place to spend a night in Clarksdale. "
A verified traveler stayed at Quality Inn
Posted 10 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near Clarksdale
More Hotel Options in Clarksdale
- Adventure Hotels in Clarksdale
- Cheap Hotels in Clarksdale
- Family Hotels in Clarksdale
- Golf Hotels in Clarksdale
- Historic Hotels in Clarksdale
- Hotels with Bars in Clarksdale
- Hotels with Free Parking in Clarksdale
- Hotels with WiFi in Clarksdale
- Hotels with a Pool in Clarksdale
- Hotels with smoking rooms in Clarksdale
- Luxury Hotels in Clarksdale
- Pet-friendly Hotels in Clarksdale
- Shopping Hotels in Clarksdale
More Accommodation Types in
- Vacation Homes in Mississippi
- Condo Rentals in Mississippi
- Cottages in Mississippi
- Apartments in Mississippi
- Cabin Rentals in Mississippi
- Motels in Mississippi
- B&B in Mississippi
- Villas in Mississippi
- Guest Houses in Mississippi
- Farmstay in Mississippi
- Resorts in Mississippi
- Lodges in Mississippi
- Aparthotels in Mississippi
- Chalets in Mississippi
- RV Parks in Mississippi
- Inns in Mississippi
- Castles in Mississippi
- Hostels in Mississippi
- Treehouses in Mississippi
Hotels near popular Clarksdale Attractions
- Hotels near Delta Blues Museum
- Hotels near Coahoma Community College
- Hotels near Red's Lounge
- Hotels near Hambone Art Gallery
- Hotels near Rock N' Roll & Blues Heritage Museum
- Hotels near Quapaw Canoe Company
- Hotels near The Holy Moly Theatre
- Hotels near New Roxy
- Hotels near Carnegie Public Library
- Hotels near Mississippi River
Clarksdale Hotels by Star Rating
Explore more hotels
- Charming 1-bedroom house in fabulous Clarksdale with WiFi
- Casa D’Amore!!!! Adorable home less than 1/2 mile from downtown Clarksdale
- Get to BLUES-in' at Rusty's Roost, adjacent to downtown Clarksdale, MS
- Sunflower Suite on the River
- Cottage on riverbank one mile from Clarksdale in gated community
- Clarksdale Home: Close to Music Festivals!
- Walk Downtown: Home w/ Yard in Clarksdale
- Walk Downtown: Home w/ Yard in Clarksdale
- Clarksdale Home: Close to Music Festivals!
- High Cotton Condos
- Lovely Clarksdale Studio < 2 Mi to Downtown!
- Cotton House, Cleveland, a Tribute Portfolio Hotel
- Motel 6 Cleveland, MS - Delta State University
- Holiday Inn Express Hotel & Suites Cleveland by IHG
- Delta Inn
- Isle Casino Hotel Lula
- Quality Inn & Suites
- Quality Inn
- Honnoll's High Cotton Guesthouse
- Welcome to this charming 4-bedroom home, perfect for seeking a relaxing getaway.