A coastal fortress with a stone wall and a tiled-roof building.

Find 5 Star Hotels in Syracuse from SAR 341

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Syracuse 5 Star Hotels

Our top choices for Syracuse 5-star hotels

1. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
5.0 star property
Ortigia
9.0 out of 10, Wonderful, (641 reviews)
"The hotel is conveniently located and balcony restaurant and bar had a great view."
United States
SEAN
The price is SAR 915
SAR 1,048 total
includes taxes & fees
21 Nov - 22 Nov
Grand Hotel Ortigia Siracusa

2. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (286 reviews)
"Good option to stay close to downtown and very exclusive hotel. Breakfast is really good."
Mexico
ALFONSO
The price is SAR 942
SAR 1,078 total
includes taxes & fees
29 Nov - 30 Nov
Ortea Palace Hotel, Sicily, Autograph Collection

3. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
5.0 star property
Ortigia
9.2 out of 10, Wonderful, (111 reviews)
"Absolutely beautiful hotel and in a perfect location with beautiful sea view. Wonderful and attentive staff."
United States
nadia
Grand Hotel Des Ètrangers - The Leading Hotels of the World

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (302 reviews)
"Kind and attentive staff. Beautiful property."
United States
Rene
The price is SAR 487
SAR 578 total
includes taxes & fees
13 Dec - 14 Dec
Caportigia Boutique Hotel

5. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (225 reviews)
"Gorgeous property in a fabulous secluded location within a short driving distance to Syracuse. Free parking on site with electric chargers. Lovely breakfast buffet with cooked options available. Spa area was very modern and well looked after. Would definitely recommend."
United Kingdom
Kathryn
Dimora Caiammari Luxury Hotel & Spa

6. Minareto

Minareto
5.0 star property
Syracuse
8.8 out of 10, Excellent, (283 reviews)
"The beach options are excellent but the rooms need updating. The hot tubs were not hot and the showers were very simple and old."
United States
Camille
The price is SAR 1,081
SAR 1,231 total
includes taxes & fees
17 Nov - 18 Nov
Minareto

7. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
5.0 star property
Syracuse
9.4 out of 10, Exceptional, (99 reviews)
"A very well maintained hotel. An excellent pool. Incredibly helpful staff even though we speak very limited Italian and an exceptional breakfast."
Australia
Nicholas
The price is SAR 999
SAR 1,694 total
includes taxes & fees
16 Nov - 17 Nov
Wellness & Spa Hotel Principe di Fitalia
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.
Still don't see what you're looking for?
See all properties in Syracuse.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

An ancient amphitheater with stone ruins and a grassy field.

Top Syracuse Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Syracuse?
Prepare for 5-star opulence at Grand Hotel Ortigia Siracusa, Ortea Palace, Sicily, Autograph Collection or Grand Hotel Des Ètrangers. These are some of the best stays in Syracuse based on Expedia customer reviews. Book one and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Syracuse?
How much you pay for a 5-star hotel in Syracuse depends on factors like when you plan to go and the length of your vacation. Our insider tip for bagging the best deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

  • Search for the lowest price per night from SAR 341

What makes a hotel 5 stars in Syracuse?
From high-end restaurants and fitness centers to swimming pools and superior bedding, the 5-star experience in Syracuse is all about luxury and relaxation. But it calls for more than just upscale amenities to get a 5-star rating. Hotels also have to deliver outstanding guest services like massage treatments, laundry and dry cleaning and 24-hour room service.