Find 5 Star Hotels in Southeast Missouri, MO

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Check availability on Southeast Missouri 5 Star Hotels

Compare Southeast Missouri 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southeast Missouri.
Urban Lofts

Urban Lofts

104 North Jackson Street, Perryville, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

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