A calm river with clear water, surrounded by dense trees and rocky banks.

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Check availability on O Brien 5 Star Hotels

Tonight
27 Sep - 28 Sep
Tomorrow
28 Sep - 29 Sep
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

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A calm river surrounded by trees reflecting in the water.

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in O Brien?
The amount you pay for a 5-star hotel in O Brien can vary according to when you want to travel and how long you plan to be away, among several factors. Take advantage of our price per night filter and other search tools to score the best deal on a plush stay.
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What makes a hotel 5 stars in O Brien?
From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in O Brien is all about luxury and comfort. But it requires more than just top-notch perks to receive a 5-star rating. Accommodations also have to provide remarkable guest services like in-room massage treatments, on-site laundry and room service any time night or day.
Are there any 5-star all-inclusive resorts in O Brien?
Expedia's filters are the quickest way to narrow down what you want. Select "5-star" and "All inclusive" to see the most upscale properties in O Brien where your meals, lodging, entertainment and activities are included in the price. At these stays, your vacation is pure relaxation and indulgence from the moment you pull up to the entrance.