Find 5 Star Hotels in Lower Keys, FL

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Check availability on Lower Keys 5 Star Hotels

Compare Lower Keys 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Keys.
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Big Pine Key
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Keys

Explore the relaxing area of Lower Keys—parks, boating, and sights from Florida Keys Beaches to Sugarloaf Beach.

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Big Pine Key featuring a river or creek, a bay or harbor and general coastal views