A coastal landscape with a sandy beach, clear turquoise waters, and a rocky outcrop.

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Check availability on Karlovassi 5 Star Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Karlovassi 5-star hotels

A modern resort with a central pool, lounge areas, and mountain views.

1. Casa Cook Samos

Casa Cook Samos
5.0 star property
Samos
9.4 out of 10, Exceptional, (153 reviews)
"Peaceful hotel with helpful staff"
United Kingdom
Margaret Anne
Casa Cook Samos
A serene outdoor setting with a pool, a person in a white dress, and a view of the sea.

2. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
5.0 star property
Samos
9.6 out of 10, Exceptional, (122 reviews)
"Amazing place: clean, plenty of sunbeds on perfect private beach, lots of breakfast options"
Germany
Artsem
Proteas Blu Resort - Adults Only
A coastal hotel with a swimming pool, surrounded by greenery and overlooking the sea.

3. Doryssa Seaside Resort

Doryssa Seaside Resort
5.0 star property
Samos
8.8 out of 10, Excellent, (186 reviews)
"A gorgeous property, great location, courteous staff… would def stay there again!! Perfect room!!😊"
United States
Athanasios
Doryssa Seaside Resort
An infinity pool with lounge chairs and a view of a coastal town.

4. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
5.0 star property
Samos
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Karlovassi.
Hydrele Beach Hotel

Hydrele Beach Hotel

Potokaki beach, Pythagorion Samos Samos island
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Karlovassi

This former tannery town charms with its neoclassical buildings and the bustling harbor where fishing boats deliver fresh seafood daily. Explore the University of the Aegean campus, then head to nearby Potami Beach where three cascading waterfalls reward hikers with natural swimming pools.

See all hotels in Karlovassi
A coastal landscape with a sandy beach, clear turquoise waters, and a rocky outcrop.
Photo by Stephanie Gehring
Open Photo by Stephanie Gehring

Top Karlovassi Hotel Reviews

Casa Cook Samos

Casa Cook Samos

10/10 Excellent
"Peaceful hotel with helpful staff"
Margaret Anne 7-night trip
Posted 11 days ago
Casa Cook Samos

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Karlovassi?
How much you pay for a 5-star hotel in Karlovassi can vary according to when you prefer to travel and how long you plan to be away, among other factors. Take advantage of our price per night filter and other search tools to score the best rate on a high-end stay.

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What makes a hotel 5 stars in Karlovassi?
Flawless guest service is the defining feature of every 5-star hotel in Karlovassi. From the moment you enter the lobby, staff attend to your every whim, whether arranging customized tours or providing in-room massage treatments. Additionally, hotels have to feature upscale amenities to be entitled to a 5-star rating. These can include luxury baths, a wellness center, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Karlovassi?
Find a luxurious retreat that includes your lodging, meals, drinks and entertainment in Karlovassi with Expedia's filter tool. Search for resorts rated 5 stars and select the "All inclusive" filter. Have a look at what's included in the upfront price. That way, you'll be ready to maximize all the premium perks as soon as you arrive.