A brick wall with a white sign that reads "Missouri US 66".

Find 5 Star Hotels in Cuba, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Cuba 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Cuba

Murals and classic cars line the historic Route 66 corridor where locals gather at Cuba's famous Wagon Wheel Motel. Take a self-guided tour of the 'Viva Cuba' outdoor art displays, then sample homestyle cooking at Missouri Hick's BBQ when hunger strikes.

See all hotels in Cuba
A brick wall with a white sign that reads "Missouri US 66".

Top Cuba Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Cuba?
The amount you pay for a 5-star hotel in Cuba depends on things such as when you plan to travel and the length of your getaway. Our top tip for landing an awesome deal? Use our pricing filters to check out the available options for your selected dates.

  • Search for the lowest price per night

What makes a hotel 5 stars in Cuba?
From high-end restaurants and all-day fitness centers to pools and the finest bedding, the 5-star experience in Cuba is all about indulgence and comfort. But it calls for more than just upscale conveniences to earn a 5-star rating. Stays must also offer remarkable guest-centric services like in-room massage treatments, on-site dry cleaning and laundry and room service any time night or day.
Are there any 5-star all-inclusive resorts in Cuba?
Find a luxurious retreat that includes your lodging, meals, drinks and entertainment in Cuba with our handy filters. Search for properties with a 5-star rating and click on the "All inclusive" filter. Double-check what's included in the upfront price. That way, you're ready to take advantage of all the premium perks when you arrive.

Explore a world of travel with Expedia