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Find 5 Star Hotels in Chillicothe, MO

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Check availability on Chillicothe 5 Star Hotels

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Chillicothe.
Dawson Retreats 407

Dawson Retreats 407

407 East Mcgaughy Street Hamilton MO
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8/10 Very Good! (1 review)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Chillicothe and related destinations

Nestled along the Wabash River, this family-friendly small town invites visitors to explore its charming Grayville Public Library and relax at Memorial Park. After enjoying local attractions, take a short drive to discover the intriguing Labyrinth State Memorial and artistic treasures at New Harmony Gallery of Contemporary Art.

See all hotels in Grayville
A black and red train with the number 8701 at a train station.

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Chillicothe?
You'll find a variety of pricing options for a 5-star hotel in Chillicothe on Expedia. How much you'll pay will depend on when you want to travel, trip length and other factors. Compare all of the available properties for your chosen dates and make use of our pricing and other filters to discover the ideal luxury stay.

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What makes a hotel 5 stars in Chillicothe?
In Chillicothe, a hotel needs to provide a specific level of top-notch amenities to earn 5 stars. These can include on-site gyms, gourmet restaurants, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their guest-centric service. You can expect things like concierge services, nightly turn-down services and in-room massage. Some may also offer thoughtful touches like welcome gifts.
Are there any 5-star all-inclusive resorts in Chillicothe?
Find an indulgent retreat that includes your lodging, meals, bar and entertainment in Chillicothe with the help of our filter tool. Search for properties with a 5-star rating and select the "All inclusive" filter. Double-check what's included in the upfront price. That way, you can take full advantage of the many perks on offer when you get there.