
Find 4 Star Hotels in Mayo, FL
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Mayo 4 Star Hotels
Our top choices for Mayo 4-star hotels

9.8 out of 10, Exceptional, (7 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Mayo
Paddle through crystal-clear waters at Lafayette Blue Springs State Park where swimming and snorkeling reveal underwater caves and limestone formations. Explore the peaceful Suwannee River by kayak or visit Perry Spring, where locals gather for refreshing dips during hot summer afternoons.

Top Mayo Hotel Reviews
Frequently asked questions
Explore a world of travel with Expedia
Explore more hotels
- Econo Lodge Live Oak
- Holiday Inn Express Hotel & Suites PERRY by IHG
- Regency Inn
- Lake Retreat of Steinhatchee- bring your RV to the place for fun and memories!!
- Steinhatchee River Inn
- Super 8 by Wyndham Madison
- Peaceful cabin on the Cochee river w/ 4 acres land
- Putnam Lodge Hotel and Spa
- Cabin on Sante Fe Inlet in Three River Estates (walking distance to park)
- Cozy Log Cabin Retreat on the Santa Fe River – Nature, Kayaking & Relaxation!
- ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River
- Ichetucknee Springs/Ginnie Springs/Santa Fe River at the Hideaway Cottage
- Riverfront home in Branford on the Sante Fe and access to the Ichetucknee!
- Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
- Dekle Beach Darling - Beautiful Sunsets and Great Fishing
- Carriage Inn Motel
- Riverfront Cabin, Ichetucknee River
- Scallop and Fishing Paradise
- Come stay and relax in our newly renovated home by the Ichetucknee River


