Find 4 Star Hotels in Chillicothe, MO

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Check availability on Chillicothe 4 Star Hotels

Tonight
31 Aug - 1 Sep
Tomorrow
1 Sep - 2 Sep
Next weekend
5 Sep - 7 Sep
In two weeks
12 Sep - 14 Sep

Compare Chillicothe 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Chillicothe 4-star hotels

Cameron Suites
Deluxe Apartment, Park View | Park view

Cameron Suites

4.0 star property
Cameron Suites
Dawson Retreats 407
Family Townhome, Multiple Beds | Private kitchen | Fridge, microwave, oven, dishwasher

Dawson Retreats 407

4.0 star property
8.0 out of 10, Very Good, (1)
"Perfect surroundings for a girls getaway to Missouri Star Quilt Co. Newly remodeled home, walking distance to shops and restaurants. Limited choice of restaurants available, but a Subway was open late. Grocery/market was also available in town. The three bedrooms were spacious and brightly decorated. The living room was comfortable with a large tv. A basic sewing machine and cutting mat were available for use. I wish I was staying longer to work on some projects. My stay was on a chilly...
Dawson Retreats 407
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Chillicothe and related destinations

Start your day at the Historical Society Museum where locals proudly showcase coal mining artifacts and regional treasures. Spend evenings at Mahr Park's walking trails and fishing lakes, or catch live bluegrass at the Glema Mahr Center during summer concert series.

See all hotels in Madisonville
Early morning scouting scenic area on outskirts of Madisonville. This pond was created by strip mining which is prevalent in Western Kentucky.
Photo by Bill Griffin
Open Photo by Bill Griffin

Top Chillicothe Hotel Reviews

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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Chillicothe?
We can help you easily locate the perfect 4-star hotel for your trip to Chillicothe. Use our filter tool to tailor your search by things like budget, amenities and hotel star rating and get access to fantastic deals in a couple of clicks.

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What's the difference between 5-star and 4-star hotels in Chillicothe?
If you choose to spend your vacation at a 4-star hotel in Chillicothe, you'll typically find plenty of amenities to ensure you're comfortable, such as a gym, restaurant and pool. You can look forward to top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few extra bells and whistles — think on-site spas, 24-hour front desk and nightly turndown services. You'll most likely get more amenities and first-class services at a 5-star retreat, though both are terrific options for luxury travelers.
Does Chillicothe have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your dream resort in Chillicothe where just about everything is taken care of, from your accommodations to your food, entertainment and activities. We can also help you find standard 4-star stays in and around this sought-after destination.