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Find 4 Star Hotels in Cape Girardeau, MO

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Check availability on Cape Girardeau 4 Star Hotels

Tonight
22 Jul - 23 Jul
Tomorrow
23 Jul - 24 Jul
This weekend
25 Jul - 27 Jul
Next weekend
1 Aug - 3 Aug

Compare Cape Girardeau 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Learn more about Cape Girardeau

Trip time! Discover the riverfront, history, and university life in Cape Girardeau.

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The Bar - this was one location Gone Girl was filmed at!
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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Cape Girardeau?
Expedia can help you easily locate the ideal 4-star hotel for your trip to Cape Girardeau. Use our handy filter tool to fine-tune your search by things like price, amenities and star rating and get access to fabulous deals in a couple of clicks.

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What's the difference between 5-star and 4-star hotels in Cape Girardeau?
Offering a welcoming traveler experience and upscale décor, 4-star hotels are a great option for your Cape Girardeau vacation. These kinds of accommodations generally feature loads of useful amenities that make it a breeze to unpack and recharge — think complimentary bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to spoil you with luxury perks and amenities. 24-hour front desk, oversized bathrooms and world-class dining are typically included at these plush properties.
Does Cape Girardeau have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Cape Girardeau where everything is taken care of, from your room to your food, activities and entertainment. We can also help you find standard 4-star stays in and around this popular destination.