Search Vacation Homes in Santa Fe Depot

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
24 Oct - 26 Oct
In two months
5 Dec - 7 Dec
In three months
2 Jan - 4 Jan
In four months
30 Jan - 1 Feb

Vacation Homes in Santa Fe Depot

Across OU Medical+Children's Hospital | POOL TABLE
Living area

Across OU Medical+Children's Hospital | POOL TABLE

9.2 out of 10, Wonderful, (9)
"Enjoyed the stay. Location was perfect for what we needed. I would stay here again if the opportunity was presented."
The price is SAR 656
SAR 1,613 total
includes taxes & fees
8 Oct - 9 Oct
Across OU Medical+Children's Hospital | POOL TABLE
Cozy 2-bedroom, 2-bath house in charming Oklahoma City
Fridge, microwave, oven, stovetop

Cozy 2-bedroom, 2-bath house in charming Oklahoma City

Cozy 2-bedroom, 2-bath house in charming Oklahoma City
Howes Capitol–3 in 1-near OU Med, Bricktown, Arena
Fridge, microwave, oven, stovetop

Howes Capitol–3 in 1-near OU Med, Bricktown, Arena

9.2 out of 10, Wonderful, (7)
"We were under the impression that all the units were connected inside the house at the time of booking. The listing has been reworded since then. We had to walk outside to get to each other, which we did not plan on. But we still enjoyed the rental and it was clean and tastefully decorated. The fan in one of the bedrooms was not working, which made for hot sleeping. We did tell our host and they said they would look into it. The location was great. Overall, we were pleased with our...
Howes Capitol–3 in 1-near OU Med, Bricktown, Arena
Modern Private Townhome *Downtown OKC * Balcony *OU Med
Fridge, microwave, oven, stovetop

Modern Private Townhome *Downtown OKC * Balcony *OU Med

9.6 out of 10, Exceptional, (10)
"Loved it ! Definitely recommend! "
Modern Private Townhome *Downtown OKC * Balcony *OU Med
Midtown Historic Bungalow
Exterior

Midtown Historic Bungalow

2.0 star property
10.0 out of 10, Exceptional, (4)
"We loved our weekend stay at this cute little house!"
Midtown Historic Bungalow
Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown
Dining

Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown

10.0 out of 10, Exceptional, (117)
"Had a wonderful time in this beautiful home. Had everything we needed. Comfortable beds super vlean just a great place to stay!!"
Capitol House - Historic 5bed/3bath house near OUHSC,State Capitol and Downtown
Beautifully Remodeled 3B1.5B W/ King Bed By OU Med
Fridge, microwave, oven, stovetop

Beautifully Remodeled 3B1.5B W/ King Bed By OU Med

9.2 out of 10, Wonderful, (10)
"The house was sparkling clean, nicely decorated with comfy beds. We had a great time there and would definitely stay again."
Beautifully Remodeled 3B1.5B W/ King Bed By OU Med
Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking
Interior

Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking

10.0 out of 10, Exceptional, (7)
"It was a good overall experience for a family with kids to stay in this property. Thanks Colten!!!"
Cozy Craftsman Bungalow in the heart of downtown OKC with AC, Workspace, Parking
Beautiful 4 Bed House With King Bed & HOA Park
TV, fireplace

Beautiful 4 Bed House With King Bed & HOA Park

9.2 out of 10, Wonderful, (11)
"The inside was very clean. The hosts were very prompt and courteous with answering any questions or recommendations that we had or asked for. ."
Beautiful 4 Bed House With King Bed & HOA Park
Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!
Property grounds

Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!

9.8 out of 10, Exceptional, (38)
"Great place, location, and communication! Would definitely recommend to others and would book again. "
Casa Mahogany - East Bricktown's Contemporary Gem. HOT TUB!
Spacious 4 Bed House With King Bed & Playground
Fridge, microwave, oven, stovetop

Spacious 4 Bed House With King Bed & Playground

9.4 out of 10, Exceptional, (10)
"Great property, clean, comfy beds...everything we needed...and the communication was excellent!"
Spacious 4 Bed House With King Bed & Playground
Quiet 4 Bed Home With HOA Park
Fridge, microwave, oven, stovetop

Quiet 4 Bed Home With HOA Park

8.8 out of 10, Excellent, (5)
"This VRBO was clean and quiet. Cute space "
Quiet 4 Bed Home With HOA Park
Blue Bungalow near OU Med/Downtown 0 cleaning fee
Exterior

Blue Bungalow near OU Med/Downtown 0 cleaning fee

8.6 out of 10, Excellent, (8)
"Everything was as depicted. Nice home."
Blue Bungalow near OU Med/Downtown 0 cleaning fee
Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly
Fridge, microwave, oven, stovetop

Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly

9.2 out of 10, Wonderful, (19)
"The kitchen was well equipped, property was clean, and just what we need for our two small dogs."
Newly Renovated Villa|🚶1min from Plaza District|Hot Tub|🎱Pool Table|🐶Friendly
"The Ivyson" on 10th Urban Core Midtown OKC
Interior

"The Ivyson" on 10th Urban Core Midtown OKC

6.0 out of 10, (1)
"The place looked just like the pictures. Nicely decorated and very clean. The downstairs bed is bigger than it looks in the picture. My two teen girls slept in it just fine. My only complaint is it smelled like someone had smoked weed in the house. It gave two of us really bad headaches and one of my kids got sick to her stomach from it. Overall we loved the place…except the weed smell! "
"The Ivyson" on 10th Urban Core Midtown OKC
Upscale living in Downtown OKC. Unbeatable location and pet friendly!
Outdoor dining

Upscale living in Downtown OKC. Unbeatable location and pet friendly!

2.0 out of 10, (1)
"Got confirmation at booking and 48 hours prior to check in. Then no door code, 3 hours before anyone could get ahold of owner who had no knowledge of booking. I had to get another room. "
Upscale living in Downtown OKC. Unbeatable location and pet friendly!
Entire Lincoln Lodge by OU Medical
TV, offices

Entire Lincoln Lodge by OU Medical

9.6 out of 10, Exceptional, (13)
"Love the property! Very clean, nicely decorated, quiet neighborhood. All the basics were supplied and everything was very very comfortable, but don’t look for luxury bedding if that’s your thing. Tons of space for everyone. Huge bonus: you don’t have to spend the morning of checkout stripping beds, mopping floors, cleaning bathrooms, etc. They do all that!!! Amazing and made things stress free. Would definitely stay again! "
Entire Lincoln Lodge by OU Medical
Val's Eclectic Classen Cottage
Dining

Val's Eclectic Classen Cottage

9.4 out of 10, Exceptional, (35)
"Great place to stay during the Christmas holiday season with our family and central location to Downtown OKC."
Val's Eclectic Classen Cottage
Brick View Studio in downtown Oklahoma City
Living area

Brick View Studio in downtown Oklahoma City

2.0 star property
Brick View Studio in downtown Oklahoma City
Chic 50s Time Capsule Downtown/OU Med/OK Capitol
Exterior detail

Chic 50s Time Capsule Downtown/OU Med/OK Capitol

9.8 out of 10, Exceptional, (11)
"A great place in a good location. Loved the 50’s and art vibe. Especially enjoyed the screened in porch. Everything was as described. No problems; will stay again."
Chic 50s Time Capsule Downtown/OU Med/OK Capitol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Fe Depot Hotel Reviews

Clarion Pointe OKC Airport

Clarion Pointe OKC Airport

10/10 Excellent
"The gym is well equipped The balcony has a great view , the rooms are clean and steady "
Ketsia 2-night trip
Posted 1 day ago
Clarion Pointe OKC Airport