Search Vacation Homes in Murphysboro

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Compare 83 Vacation Homes in Murphysboro with updated reviews, rates, and availability.

Amazing, amenity loaded golf course retreat steps from dining and entertainment!
10.0 out of 10, Exceptional, (10)
"In Marion for a family wedding. Perfect place for all of us (adult children and teenage grandchildren and pre-teen great grandchildren). Dramatic great room overlooking 5th tee. Got to review the golfers as an added benefit. Looks like a good spot for a getaway golf weekend."
Amazing, amenity loaded golf course retreat steps from dining and entertainment!
Best location! Next door to full service marina and bar/restaurant.
9.4 out of 10, Exceptional, (89)
"Cute house, right on the lake. Came down for college graduation, but seemed to spend more time at the house and lake thank anything else. House had every amenity needed, including a boat dock and electricity. On a whim decided to bring a boat along, and make a short vacation out of the trip. Looking forward to another trip down! Hopefully this house will be available on our next booking!"
Best location! Next door to full service marina and bar/restaurant.
Country, hideaway cabin close to town, 15 minutes from wineries
10.0 out of 10, Exceptional, (4)
"Property was great!"
Country, hideaway cabin close to town, 15 minutes from wineries
Save an average of 15% on thousands of hotels when you're signed in
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
10.0 out of 10, Exceptional, (80)
"Very quite and peaceful Exactly what I wanted!"
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Notting Hill Cottage
9.6 out of 10, Exceptional, (277)
"Excellent location for hiking, exploring the wineries, or just getting away. The hot tub after a long day of hiking in the Shawnee was definitely a plus."
Notting Hill Cottage
Lake Front. Large shaded deck with Covered Dock access. Fire pit.
9.8 out of 10, Exceptional, (54)
"Our family of 5 absolutely loved our stay at this property. There was plenty of room for our family of 5, the property decor was beautiful, the kitchen was well stocked with everything you need to cook and the beds were soooo comfortable. We enjoyed spending our evenings on the deck and using the gas grill to cook and fishing off the dock. The kids enjoyed using the water trampoline. Brad was easy to get ahold of and welcoming. We will definitely be returning and would recommend this spot to...
Lake Front. Large shaded deck with Covered Dock access. Fire pit.
Comfy Clean & Cute
9.8 out of 10, Exceptional, (16)
"First time I’ve stayed somewhere other than a motel. Very nice quiet would recommend."
The price is SAR 281
SAR 804 total
includes taxes & fees
4 Jum. II - 5 Jum. II
Comfy Clean & Cute
Beautiful Lake Getaway
10.0 out of 10, Exceptional, (8)
"Place was very nice. Met and exceeded my expectations."
Beautiful Lake Getaway
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
9.8 out of 10, Exceptional, (127)
"Lots of room, plenty of games & ect. Everything we wanted to see was close. The kitchen had everthing we needed to cook. Very nice calming outdoor area."
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
Brick Estate with pool in Quiet Carbondale Neighborhood
9.4 out of 10, Exceptional, (72)
"This is a beautiful house. There are areas where repair is needed, however it did not negatively affect our stay on any way. Clean, quiet, excellent location and most of all, we were incredibly comfortable."
Brick Estate with pool in Quiet Carbondale Neighborhood
Peaceful Custom Carbondale Home w/ Pool, Near SIU!
9.2 out of 10, Wonderful, (54)
"Stayed with a group of friends for a wedding nearby. Property was clean and accurate to the online listing. Wish the weather would have been nice enough to use the pool space! Check in and out were smooth processes and communication with the property manager was super easy. Would recommend."
Peaceful Custom Carbondale Home w/ Pool, Near SIU!
Wine Trail, Cozy Cabin plus hot tub
10.0 out of 10, Exceptional, (72)
"Very clean and comfortable. Close to many wineries. Great sunset view from the hot tub. Quiet setting. Had a nice relaxing weekend. Would book again.❤️"
Wine Trail, Cozy Cabin plus hot tub
Millers 2 lakehouse. Pontoon available to rent
9.8 out of 10, Exceptional, (89)
"It was an awesome place to stay. The location on the lake was in a cove, which is a plus. We enjoyed spending time on the large porch. The house was amazing. We had three couples, and each of us had a large bedroom and a bathroom. We would definitely stay there again."
Millers 2 lakehouse. Pontoon available to rent
Country Chateau w/ HOT TUB - Wineries + Hiking
10.0 out of 10, Exceptional, (3)
"I came here for a weekend away with my siblings and our partners and it was so much fun! The property is gorgeous and the house is pristine. Would absolutely visit again!!"
The price is SAR 1,440
SAR 1,756 total
includes taxes & fees
24 Jum. II - 25 Jum. II
Country Chateau w/ HOT TUB - Wineries + Hiking
* On the Wine Trail * Hot Tub * Wi-Fi *
9.8 out of 10, Exceptional, (203)
"This lovely little place was perfect for my two college-aged children and me to decompress, hike, soak, eat and laugh. Great experience!"
* On the Wine Trail * Hot Tub * Wi-Fi *
Hot Tub Overlooking Sunset Ridge | Sleeps 6
10.0 out of 10, Exceptional, (6)
"We ladies had a great couple of days in wine country. It was so nice for all four of us to have our own bed. The house is roomy and was very clean with all the amenities needed. We would recommend it! Be aware, it is closer to the road than we expected, but there was no traffic noise. Also, there are no shades on the main floor windows. Nice location. Close to the wine trail and Carbondale, even a Dollar General. Great stay!"
The price is SAR 1,093
SAR 1,359 total
includes taxes & fees
1 Raj. - 2 Raj.
Hot Tub Overlooking Sunset Ridge | Sleeps 6
On the Wine Trail - Daily Deer Viewing - Wonderful Views - Wi-fi - Rural
10.0 out of 10, Exceptional, (105)
"Very clean and comfortable"
On the Wine Trail - Daily Deer Viewing - Wonderful Views - Wi-fi - Rural
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
10.0 out of 10, Exceptional, (4)
"The property was just what we needed for several families getting together. Thank you!"
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
Lakefront Boho Chic 4BR | Playground & Waterslide
10.0 out of 10, Exceptional, (12)
"Had a great time fishing with family. Would definitely come back. The host was very responsive and helpful!"
Lakefront Boho Chic 4BR | Playground & Waterslide
Spacious Open Concept Home in safe residential subdivision in So IL
10.0 out of 10, Exceptional, (13)
"I would recommend this home for anyone coming to the area. Great place to stay. Everything you need for a couple days or longer. Close to everything, very quiet neighborhood. Couldn't figure out how to lock the front door when leaving and had to call for help. Return call was very quick. There's a trick to locking the door. Must be one for the dishwasher too because I was unable to get it started when we left. Would definitely stay again if we had a group. Loved the color themes in the bedrooms."
Spacious Open Concept Home in safe residential subdivision in So IL
Don't see what you're looking for?
See all available properties in Murphysboro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Murphysboro

Murphysboro Retreat w/ Deck Near Kinkaid Lake!
10.0 out of 10, Exceptional, (8)
"It was very peaceful and relaxing. Close to town."
Murphysboro Retreat w/ Deck Near Kinkaid Lake!
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
10.0 out of 10, Exceptional, (83)
"Adorable modern cabin in a very secluded area on the Wine Trail. We had a great time - the hot tub was so relaxing after a day at the a wineries. Loved watching the cows and the bull at the neighboring property, and we even saw deer on Sunday morning. Will definitely book again!"
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
New cabin in the woods with private hot tub
10.0 out of 10, Exceptional, (74)
"Beautiful property, great cabin, roomy and super comfortable. The hot tub was great, the ambience of the woods, perfect!"
New cabin in the woods with private hot tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent reviews of Murphysboro hotels
Expedia verified reviews