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Check prices for these dates

In two weeks
19 Dec - 21 Dec
In two months
30 Jan - 1 Feb
In three months
27 Feb - 1 Mar
In four months
27 Mar - 29 Mar

Apartments in St. Charles

Fridge, microwave, oven, stovetop
Big River Inn - 3 bedroom apartment in Alma

Apartment in Alma

8.6 out of 10, Excellent, (14)
"Great place in the heart of Alma"
United States
Kevin B.
The price is SAR 321
SAR 864 total
includes taxes & fees
8 Dec - 9 Dec
Big River Inn - 3 bedroom apartment in Alma
Dining
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Apartment in Rochester

9.6 out of 10, Exceptional, (22)
"Great location "
United States
Peary S.
The price is SAR 225
SAR 726 total
includes taxes & fees
13 Dec - 14 Dec
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Exterior
Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!

Apartment in Rochester

10.0 out of 10, Exceptional, (3)
"Very nice and convenient stay. Everything we needed and extremely well maintained room and kitchen. Loved it and the responsiveness out our hosts!"
United States
Rick H.
The price is SAR 360
SAR 502 total
includes taxes & fees
14 Dec - 15 Dec
Studio Suite! Free Breakfast + Shared Pool & Hot Tub. Great for Business Travelers!
Interior
Charming 2-bedroom apartment in delightful Rochester with WiFi, AC

Apartment in Meadow Park

10.0 out of 10, Exceptional, (1)
"Quiet, clean and in a friendly neighborhood. Staying there took some of the stress out of my Mayo Clinic visits. I always worry about my follow-up visits, but a good quiet place to stay helps me let that go."
United States
Maria L E.
The price is SAR 357
SAR 755 total
includes taxes & fees
8 Dec - 9 Dec
Charming 2-bedroom apartment in delightful Rochester with WiFi, AC
Dining
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

Apartment in Rochester

10.0 out of 10, Exceptional, (8)
"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"
United States
Jessica Z.
The price is SAR 357
SAR 1,002 total
includes taxes & fees
12 Dec - 13 Dec
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Apartment in Downtown Rochester

3.0 star property
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is SAR 581
SAR 669 total
includes taxes & fees
22 Dec - 23 Dec
Broadway Plaza, Trademark Collection by Wyndham
Bar (on property)
Large and Rare 1-Bedroom Retreat with Gym, Bar, Pool & More –Pet-FriendlyOptions

Apartment in Rochester

2.0 star property
The price is SAR 484
SAR 644 total
includes taxes & fees
9 Dec - 10 Dec
Large and Rare 1-Bedroom Retreat with Gym, Bar, Pool & More –Pet-FriendlyOptions
Exterior
Free Breakfast. Pool & Hot Tub. Close to Mayo Clinic! Great for Business Travelers!

Apartment in Rochester

The price is SAR 336
SAR 473 total
includes taxes & fees
4 Jan - 5 January 2026
Free Breakfast. Pool & Hot Tub. Close to Mayo Clinic! Great for Business Travelers!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

10/10 Excellent
"Great location. Friendly staff. Easy access to Mayo Clinic’s via shuttle. Rooms were comfortable and spacious. "
Jill 3-night trip
Posted 2 days ago
Hyatt House Rochester/Mayo Clinic Area

Frequently asked questions

What's it like to stay at an apartment in St. Charles?
You might have as many choices within the heart of St. Charles, but Expedia can help you locate accommodations within the larger area with similar amenities to an apartment. When you search on Expedia, you can use the filters to search for conveniences you might find in an apartment such as a kitchen. You can also filter by similar property types like vacation homes, condos, or guest houses.
Are you thinking about apartments over traditional hotel rooms?
Offering a kitchen for convenient meals, an apartment often has more space than a traditional hotel room. Apartments are a good option for solo travelers who want to live like locals, and also for families wanting the conveniences of home.
What's the best apartment I should consider for a stay in St. Charles?
Below you'll find a top apartment in the area: Broadway Plaza, Trademark Collection by Wyndham: Located in Rochester, 20.4 mi/32.9 km from the heart of St. Charles. Includes free WiFi and separate dining areas. A fitness center and onsite laundry facilities are on site.
What can I expect from the weather during my trip to St. Charles?
Weather is only one factor, but it can really affect your travel plans, especially when you're planning an extended stay in St. Charles. The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.
What should I see in St. Charles?
While you're exploring the area, Whitewater River and Root River are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you'll find Whitewater State Park and St. Mary's University of Minnesota.
What's the best way to get to and around St. Charles?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into Rochester, MN (RST-Rochester Intl.), which is located 22.6 mi (36.4 km) from the heart of the city. If you'd like to explore around the area, you may want to rent a car for your trip.