Photo by Bill Dillard

Find Luxury Hotels in Southeast Missouri, MO

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Luxury Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Southeast Missouri Luxury Hotels

Lobby sitting area
The Riverview

The Riverview

4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (464)
"Place was nice and safe"
United States
ryan
The price is SAR 325
SAR 367 total
includes taxes & fees
14 Dec - 15 Dec
The Riverview
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1447)
"Awesome place to stay!!"
United States
Kaitlyn
The price is SAR 320
SAR 427 total
includes taxes & fees
8 Dec - 9 Dec
River City Casino & Hotel
Lobby
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4.0 star property
Frontenac
8.8 out of 10, Excellent, (1005)
"Clean room, felt like a mini apartment! The surrounding was beautiful. "
United States
Jane
The price is SAR 489
SAR 570 total
includes taxes & fees
14 Dec - 15 Dec
Hilton St. Louis Frontenac
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Very nice staff and very clean"
Jacquelyn 1-night trip
Posted 3 days ago
Pear Tree Inn Cape Girardeau Near the Medical Center

Explore a world of travel with Expedia