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Top Southeast Missouri Hotels with WiFi
Drury Inn & Suites Sikeston, MO
Sikeston
9.4 out of 10, Exceptional, (1002)
"Clean room, great location and friendly staff"
Mark
The price is SAR 338
SAR 388 total
includes taxes & fees
11 Dec - 12 Dec
Echo Bluff State Park
Eminence
9.6 out of 10, Exceptional, (216)
"Beautiful location…excellent service and facilities / grounds were clean and well kept."
William
The price is SAR 555
SAR 587 total
includes taxes & fees
8 Dec - 9 Dec
Hampton Inn Poplar Bluff
Poplar Bluff
9.4 out of 10, Exceptional, (796)
"Staff was kind and provided a lot of information during check out."
Shea
The price is SAR 348
SAR 390 total
includes taxes & fees
4 Jan - 5 January 2026
The Farmstead Hotel
Caruthersville
8.8 out of 10, Excellent, (460)
"Clean rooms and really comfortable beds!"
Andrea
The price is SAR 308
SAR 350 total
includes taxes & fees
8 Dec - 9 Dec
Drury Inn & Suites Poplar Bluff
Poplar Bluff
9.2 out of 10, Wonderful, (957)
"Delicious, well-ran breakfast and quiet peaceful hotel.
"
Janene
The price is SAR 353
SAR 398 total
includes taxes & fees
12 Dec - 13 Dec
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
8.4 out of 10, Very Good, (716)
"Stayed one night. Good rate for the Hotel "
Paul
The price is SAR 198
SAR 226 total
includes taxes & fees
8 Dec - 9 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
"Great place and staff, very accommodating!"
Megan
The price is SAR 338
SAR 381 total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Perryville by IHG
Perryville
9.2 out of 10, Wonderful, (537)
"Clean room and pleasant staff"
David
The price is SAR 327
SAR 374 total
includes taxes & fees
21 Dec - 22 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Pear Tree Inn Cape Girardeau Near the Medical Center
10/10 Excellent
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Hotels near popular Southeast Missouri Attractions
- Hotels near Southeast Missouri State University
- Hotels near Johnson's Shut-ins State Park
- Hotels near Elephant Rocks State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lake Wappapello
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- Hotels near Taum Sauk Mountain State Park
- Hotels near Alley Spring & Mill
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Sikeston, MO
- Drury Inn & Suites Jackson MO
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Cape Girardeau West
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Poplar Bluff
- Baymont by Wyndham Festus
- Hampton Inn Poplar Bluff
- Drury Inn & Suites Cape Girardeau
- Super 8 by Wyndham Farmington
- Hampton Inn Cape Girardeau I 55 East
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Best Western Plus Sikeston
- Econo Lodge
- Holiday Inn Express & Suites Perryville by IHG
- Quality Inn
- Drury Inn & Suites Hayti Caruthersville