Photo by Karen Leone
Find Family Hotels in South San Diego, CA
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on South San Diego Family Hotels
Top South San Diego Family Hotels
Best Western Americana Inn
San Ysidro
9.0 out of 10, Wonderful, (1188)
"Amazing time at this place "
Maria de Los Angeles
The price is SAR 380
SAR 432 total
includes taxes & fees
4 Jan - 5 January 2026
The Rambler
Chula Vista
9.2 out of 10, Wonderful, (1997)
"Nice staff, good location"
Joshua
The price is SAR 346
SAR 400 total
includes taxes & fees
15 Dec - 16 Dec
Hercor Hotel - Urban Boutique
Chula Vista
8.6 out of 10, Excellent, (1315)
"Great value and location "
Andrew
The price is SAR 316
SAR 348 total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn by Wyndham San Diego Chula Vista
Chula Vista
8.6 out of 10, Excellent, (1495)
"Good for a short stay "
Sandra
The price is SAR 382
SAR 420 total
includes taxes & fees
4 Jan - 5 January 2026
Comfort Inn Chula Vista San Diego South
Chula Vista
8.2 out of 10, Very Good, (1235)
"Perfect family hotel "
Lucia
The price is SAR 364
SAR 401 total
includes taxes & fees
21 Dec - 22 Dec
Motel 6 San Ysidro, CA - San Diego - Border
San Ysidro
7.0 out of 10, Good, (1469)
"exceptional "
Clarissa
The price is SAR 250
SAR 284 total
includes taxes & fees
14 Dec - 15 Dec
Quality Suites San Diego Otay Mesa
Otay Mesa
7.2 out of 10, Good, (1004)
"Beautiful place "
Joe
The price is SAR 372
SAR 423 total
includes taxes & fees
10 Dec - 11 Dec
Ayres Hotel San Diego South - Chula Vista
Otay Ranch
9.8 out of 10, Exceptional, (1115)
"The room was spotless, the staff were all super nice, & the buffet breakfast was really good. "
Sybil
The price is SAR 578
SAR 637 total
includes taxes & fees
21 Dec - 22 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top South San Diego Hotel Reviews
Hampton Inn San Diego/Mission Valley
10/10 Excellent
Explore a world of travel with Expedia
Top neighborhoods for Family Hotels
Find More Hotels near South San Diego
More Hotel Options in South San Diego
- Adventure Hotels in South San Diego
- Beach Hotels in South San Diego
- Boutique Hotels in South San Diego
- Business Hotels in South San Diego
- Casinos in South San Diego
- Cheap Hotels in South San Diego
- Golf Hotels in South San Diego
- Green Hotels in South San Diego
- Historic Hotels in South San Diego
- Hotel Wedding Venues in South San Diego
- Hotel with a Concierge in South San Diego
- Hotels with Bars in South San Diego
- Hotels with Free Parking in South San Diego
- Hotels with Hot Tubs in South San Diego
- Hotels with WiFi in South San Diego
- Hotels with a Pool in South San Diego
- Hotels with smoking rooms in South San Diego
- Luxury Hotels in South San Diego
- Pet-friendly Hotels in South San Diego
- Resorts & Hotels with Spas in South San Diego
- Romantic Hotels in South San Diego
- Shopping Hotels in South San Diego
- Waterpark Hotels in South San Diego
- Winery Hotels in South San Diego
More Accommodation Types in South San Diego
- Vacation Homes in California
- Condo Rentals in California
- Apartments in California
- Cabin Rentals in California
- Cottages in California
- Villas in California
- Motels in California
- Resorts in California
- Guest Houses in California
- Aparthotels in California
- B&B in California
- Farmstay in California
- Chalets in California
- Lodges in California
- RV Parks in California
- Hostels in California
- Inns in California
- Houseboats in California
- Condo Resorts in California
- Town Houses in California
- Castles in California
- Residences in California
- Holiday Park Resorts in California
- Ranches in California
- Country Houses in California
- Capsule Hotels in California
- Safari Tentalow in California
- Treehouses in California
Hotels near popular South San Diego Attractions
- Hotels near Las Americas Premium Outlets
- Hotels near Sesame Place San Diego
- Hotels near Chula Vista Center
- Hotels near North Island Credit Union Amphitheatre
- Hotels near Chula Vista Elite Athlete Training Center
- Hotels near Sharp Chula Vista Medical Center
- Hotels near Eastlake Country Club
- Hotels near Kaiser Permanente Otay Mesa Medical Offices
- Hotels near Chula Vista Bayside Park
- Hotels near Otay Ranch Town Center
South San Diego Hotels by Star Rating
Explore more hotels
- Sheraton Mission Valley San Diego Hotel
- Courtyard by Marriott San Diego Downtown Little Italy
- Wyndham San Diego Bayside
- Embassy Suites by Hilton San Diego La Jolla
- San Diego Marriott La Jolla
- The Dana on Mission Bay
- The Sofia Hotel
- Kings Inn San Diego
- Hotel del Coronado, Curio Collection by Hilton
- Days Inn by Wyndham San Diego Hotel Circle
- The Bristol Hotel San Diego
- GreenTree Inn San Diego Mission Bay
- DoubleTree by Hilton San Diego - Hotel Circle
- Marriott Marquis San Diego Marina
- Four Points by Sheraton San Diego
- Margaritaville Hotel San Diego Gaslamp Quarter
- Sentral Gaslamp Quarter
- California Suites Hotel
- Wyndham Garden San Diego Near SeaWorld
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area