Find Resorts & Hotels with Spas in Panama City, FL

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Check availability on Panama City Resorts & Hotels with Spas

Our top choices for Panama City hotels with a spa

Holiday Inn Resort Panama City Beach by IHG

3.5 star property
Panama City Beach
9.2 out of 10, Wonderful, (1240)
"The resort was beautiful "
United States
Esther Castellano
The price is SAR 353
SAR 583 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Resort Panama City Beach by IHG

Embassy Suites by Hilton Panama City Beach Resort

3.5 star property
Panama City Beach
8.6 out of 10, Excellent, (1131)
"Clean room and great staff "
United States
Miriam
The price is SAR 357
SAR 498 total
includes taxes & fees
16 Dec - 17 Dec
Embassy Suites by Hilton Panama City Beach Resort

BEACHFRONT CONDO NOW ACCEPTING RENTALS!!

Panama City Beach
9.2 out of 10, Wonderful, (123)
"Beautiful view somewhat dated interior. Only stayed one night as we had a week planned in Seacrest and needed one additional night. Parking was full when we arrived very late ( peak season). "
United States
George Z.
The price is SAR 338
SAR 1,623 total
includes taxes & fees
10 Dec - 11 Dec
BEACHFRONT CONDO NOW ACCEPTING RENTALS!!

Enjoy amazing ocean views in this 3rd floor condo with same level parking.

Panama City Beach
9.2 out of 10, Wonderful, (58)
"Walked into a beautiful and clean condo. Had everything we needed. Location was wonderful. "
United States
Sommer W.
The price is SAR 429
SAR 1,182 total
includes taxes & fees
10 Dec - 11 Dec
Enjoy amazing ocean views in this 3rd floor condo with same level parking.

Carillon Beach Inn by Vacasa

3.5 star property
Sunnyside
8.0 out of 10, Very Good, (82)
"The bed was super comfy. Short walk to the beach. Nice pools. The property is so nice to walk around. The coffee and wine shop was excellent!!"
United States
Robert
The price is SAR 870
SAR 1,188 total
includes taxes & fees
13 Dec - 14 Dec
Carillon Beach Inn by Vacasa

Message us about snow bird special for JanFeb!!

Panama City Beach
10.0 out of 10, Exceptional, (54)
"We had an amazing time there. Will definitely be back."
United States
Greg D.
The price is SAR 912
SAR 2,462 total
includes taxes & fees
4 Jan - 5 January 2026
Message us about snow bird special for JanFeb!!

The Pearl Hotel

4.0 star property
Rosemary Beach
9.4 out of 10, Exceptional, (192)
"Loved our stay the kind staff and clean rooms and the views and surrounding amenities! "
United States
Carrie
The price is SAR 1,800
SAR 2,248 total
includes taxes & fees
5 Jan - 6 January 2026
The Pearl Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

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Frequently asked questions

Looking for a spa hotel in Panama City?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers love the array of shops in Panama City. Discover the beaches and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Panama City?
Enjoy all that Panama City has to offer and visit Panama City Marina, Panama City Mall, and Port Panama City. If you have spare time during your trip, you might want to make a stop at St. Andrews State Park and Naval Support Activity Panama City.
What is a Panama City spa hotel?
Spa hotels in Panama City provide lodging and have an on-site spa which offers services including facials as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.