Find Family Hotels in O'Fallon, MO

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Check availability on O'Fallon Family Hotels

Our top choices for O'Fallon family-friendly hotels

Lobby
Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
O'Fallon
7.6 out of 10, Good, (1001)
"Great front desk experience, no issues booking same day!"
United States
Tracy
The price is SAR 289
SAR 341 total
includes taxes & fees
1 Jan - 2 January 2026
Comfort Inn & Suites St. Louis - O'Fallon
Lobby
Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon

3.0 star property
O'Fallon
8.4 out of 10, Very Good, (451)
"Love the stay great for families!"
United States
jeriece
The price is SAR 428
SAR 505 total
includes taxes & fees
4 Jan - 5 January 2026
Residence Inn by Marriott O'Fallon
Standard Room, 2 Queen Beds | Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area

2.0 star property
O'Fallon
6.8 out of 10, (994)
"Very run down and trash around the property, but the room was clean and comfortable for our one night stop. Convenience of the location"
United States
Natalie
The price is SAR 239
SAR 282 total
includes taxes & fees
23 Dec - 24 Dec
Super 8 by Wyndham O'Fallon MO/St. Louis Area
4 bedrooms, iron/ironing board, travel crib, free WiFi
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

O'Fallon
9.6 out of 10, Exceptional, (64)
"Great place for kids! We enjoyed the key scavenger hunt and the kids thought the bunk room was super cool! "
United States
Whitney C.
The price is SAR 672
SAR 1,498 total
includes taxes & fees
16 Dec - 17 Dec
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic
Fridge, microwave, oven, stovetop
Serene Ivory*Fireplace*Fenced Yard* Dogs Welcome!

Serene Ivory*Fireplace*Fenced Yard* Dogs Welcome!

2.0 star property
O'fallon
7.8 out of 10, Good, (7)
"Our family of six recently spent two weeks at this property and were thoroughly impressed. The home was exceptionally clean, quiet, and well-appointed, with ample linens and comfortable bedding for everyone. The soaker tub was an excellent feature that added to the overall comfort of our stay. The hosts were a pleasure to work with—professional, responsive, and always easy to reach. We would highly recommend this property to anyone seeking a well-maintained home and a seamless rental experience."
United States
J s.
The price is SAR 486
SAR 1,790 total
includes taxes & fees
11 Dec - 12 Dec
Serene Ivory*Fireplace*Fenced Yard* Dogs Welcome!
Game room
The Secret Sojourn | JZ Vacation Rentals

The Secret Sojourn | JZ Vacation Rentals

O Fallon
9.4 out of 10, Exceptional, (8)
"The house was great! plenty of space for the 4 adults and the basement gaming area was fun. Great place to stay and easy access to everything. "
United States
Randall
The price is SAR 593
SAR 1,586 total
includes taxes & fees
11 Dec - 12 Dec
The Secret Sojourn | JZ Vacation Rentals
Exterior
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

2.5 star property
St. Charles
8.0 out of 10, Very Good, (1011)
"Great breakfast, clean room, hot tub!"
United States
Tony
The price is SAR 327
SAR 376 total
includes taxes & fees
4 Jan - 5 January 2026
Hampton Inn St. Charles St. Peters
Lobby
Quality Inn

Quality Inn

2.5 star property
Foristell
8.2 out of 10, Very Good, (903)
"Easy check in and out, the staff is very nice and professional. I would stay there any time Im in the area and need a room. Highly recommended."
United States
Ivaylo
The price is SAR 314
SAR 355 total
includes taxes & fees
14 Dec - 15 Dec
Quality Inn
Lobby
Comfort Inn Near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis

2.5 star property
Pacific
8.4 out of 10, Very Good, (870)
"Staff was absolutely incredible!! Very accommodating and super sweet ladies at check in. Coffee was amazing! And beds were super comfy!!"
United States
Natalia
The price is SAR 334
SAR 383 total
includes taxes & fees
4 Jan - 5 January 2026
Comfort Inn Near Six Flags St. Louis
Lobby sitting area
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
Fenton
8.0 out of 10, Very Good, (1034)
"Very friendly staff "
United States
Amber
The price is SAR 319
SAR 368 total
includes taxes & fees
14 Dec - 15 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O'Fallon Hotel Reviews

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

10/10 Excellent
"Room was very clean, spotless no smell. Staff was great."
LaTia 1-night trip
Posted 2 days ago
Holiday Inn Express St. Louis West - O'Fallon by IHG

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Frequently asked questions

What's O'Fallon like for family-friendly vacations?
The destination of O'Fallon is a great choice if you've been thinking about a vacation with your kids. The lake views, sporting events, and cafes are just some of the things that make this an attractive family vacation spot. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 10.6 mi (17 km) from the city center.
What's the best place to stay for a family vacation in O'Fallon?
Residence Inn by Marriott O'Fallon is a hotel with an indoor pool and in-room kitchens, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in O'Fallon?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for O'Fallon is 46 inches.
What's there to see and do with your family in O'Fallon?
While you are visiting O'Fallon, you might want to round up the kiddos and make time to see interesting attractions such as CarShield Field, Alligator Creek Aquatic Center, and Mid Rivers Mall. Make sure you have lots of time for activities like St. Louis Premium Outlets and Chesterfield Sports Fusion.