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Find Family Hotels in De Soto, MO

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Check availability on De Soto Family Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top De Soto Family Hotels

Business center
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
Farmington
8.0 out of 10, Very Good, (1007)
"Room was clean , staff was friendly !"
United States
Sally
The price is SAR 204
SAR 232 total
includes taxes & fees
13 Dec - 14 Dec
Baymont Inn and Suites by Wyndham Farmington, MO
Lobby
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 star property
Arnold
9.4 out of 10, Exceptional, (1001)
"The staff was very friendly and the rooms were very nice and clean"
United States
Connie
The price is SAR 338
SAR 390 total
includes taxes & fees
11 Dec - 12 Dec
Pear Tree Inn St. Louis Arnold
Exterior
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2.0 star property
Farmington
8.0 out of 10, Very Good, (610)
"Clean, friendly staff, quiet"
United States
Stacy
The price is SAR 207
SAR 236 total
includes taxes & fees
21 Dec - 22 Dec
Super 8 by Wyndham Farmington
Lobby sitting area
Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South

2.5 star property
Festus
7.8 out of 10, Good, (908)
"Vary clean"
United States
George
The price is SAR 303
SAR 354 total
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn Festus - St Louis South
Exterior
Hampton Inn Farmington

Hampton Inn Farmington

2.5 star property
Farmington
8.8 out of 10, Excellent, (518)
"Clean room, friendly staff."
United States
William
The price is SAR 396
SAR 451 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Farmington
2 bedrooms, WiFi, bed sheets
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre

Bonne Terre
9.2 out of 10, Wonderful, (17)
"Really nice and enjoyable....would stay again"
United States
mark n.
The price is SAR 188
SAR 636 total
includes taxes & fees
13 Dec - 14 Dec
The Lux- Cozy 2-bedroom apartment with AC and WiFi in enjoyable Bonne Terre
Premium bedding, desk, iron/ironing board, free cribs/infant beds
Quality Inn Farmington

Quality Inn Farmington

2.5 star property
Farmington
7.6 out of 10, Good, (858)
"We loved it and we are still staying "
United States
Dustin
The price is SAR 191
SAR 229 total
includes taxes & fees
4 Jan - 5 January 2026
Quality Inn Farmington
Free daily buffet breakfast
Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
Farmington
8.6 out of 10, Excellent, (412)
"The staff was great!"
United States
Christopher
The price is SAR 293
SAR 929 total
includes taxes & fees
2 Jan - 3 January 2026
Holiday Inn Express & Suites Farmington by IHG
Restaurant
Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

3.0 star property
Arnold
9.6 out of 10, Exceptional, (1002)
"Clean room, comfortable bed, free breakfast, dinner and drinks every night! We had a great stay, will definitely stay again!"
United States
Jacqueline
The price is SAR 462
SAR 534 total
includes taxes & fees
14 Dec - 15 Dec
Drury Inn & Suites St. Louis Arnold
Property grounds
Peter Ray House

Peter Ray House

Maeystown
10.0 out of 10, Exceptional, (70)
"The house was wonderful, the town was delightful, and the people were very friendly! We can’t wait for our next trip!"
United States
Deborah
The price is SAR 507
SAR 831 total
includes taxes & fees
8 Dec - 9 Dec
Peter Ray House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

10/10 Excellent
"Was very good stay"
A 2-night trip
Posted 5 days ago
Baymont Inn and Suites by Wyndham Farmington, MO

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Frequently asked questions

What's De Soto like for family-friendly vacations?
The destination of De Soto is a great choice if you've been thinking about a vacation with your kids. The restaurants here makes this an attractive vacation spot for families. Arrange a flight into St. Louis, MO (SUS-Spirit of St. Louis), which is located 36.5 mi (58.8 km) from the city center.
When's the best time to book a family-friendly vacation in De Soto?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.
What's there to see and do with your family in De Soto?
While you are visiting De Soto, you might want to round up the kiddos and make time to see interesting attractions such as Redfield's Flea Market, Bonne Terre Mine, and Festus Public Library. Make sure you have lots of time for activities like Sunrise Lake Beach and Big River.